Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.

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🔗 View Article (PMID 26018159)

Published in J Virol on May 27, 2015

Authors

Xiaoying Shen1, Ryan Duffy2, Robert Howington2, Alethea Cope3, Shanmugalakshmi Sadagopal4, Haesun Park5, Ranajit Pal6, Suefen Kwa4, Song Ding7, Otto O Yang8, Genevieve G Fouda9, Roger Le Grand10, Diane Bolton11, Mariano Esteban12, Sanjay Phogat13, Mario Roederer11, Rama R Amara4, Louis J Picker5, Robert A Seder11, M Juliana McElrath14, Susan Barnett15, Sallie R Permar16, Robin Shattock3, Anthony L DeVico17, Barbara K Felber18, George N Pavlakis19, Giuseppe Pantaleo7, Bette T Korber20, David C Montefiori21, Georgia D Tomaras22

Author Affiliations

1: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA sxshen@duke.edu gdt@duke.edu.
2: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
3: Mucosal Infection & Immunity Group, Section of Infectious Diseases, Imperial College London, London, United Kingdom.
4: Department of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
5: Vaccine & Gene Therapy Institute (VGTI), Oregon Health & Science University, Portland, Oregon, USA.
6: Advanced Bioscience Laboratories Inc., Rockville, Maryland, USA.
7: Laboratory of AIDS Immunopathogenesis, Service of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
8: Department of Medicine, Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA AIDS Healthcare Foundation, Los Angeles, California, USA.
9: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA.
10: CEA, Division of Immuno-Virology-IMDIT Center, DSV, iMETI, Fontenay-aux-Roses, Inserm-U1184, Université Paris-Sud, Orsay, France.
11: Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA.
12: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
13: Sanofi Pasteur, Swiftwater, PA, USA.
14: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
15: Novartis Vaccines and Diagnostics, Inc., Cambridge, Massachusetts, USA.
16: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.
17: Institute for Human Virology, Baltimore, Maryland, USA.
18: Human Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
19: Human Retrovirus Section, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
20: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Álamos, New Mexico, USA.
21: Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
22: Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA sxshen@duke.edu gdt@duke.edu.

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