Published in Acc Chem Res on June 02, 2015
What is the DNA repair defect underlying Fanconi anemia? Curr Opin Cell Biol (2015) 1.03
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair. Mol Cell (2016) 0.77
Measurement of Endogenous versus Exogenous Formaldehyde-Induced DNA-Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry. Cancer Res (2016) 0.77
Covalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells. Chem Res Toxicol (2016) 0.77
Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases. J Biol Chem (2016) 0.77
Mutagenicity of a model DNA-peptide cross-link in human cells: Roles of translesion synthesis DNA polymerases. Chem Res Toxicol (2016) 0.75
Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins. Oxid Med Cell Longev (2016) 0.75
Dithiothreitol (DTT) Acts as a Specific, UV-inducible Cross-linker in Elucidation of Protein-RNA Interactions. Mol Cell Proteomics (2015) 0.75
Mass Spectrometry Based Tools to Characterize DNA-Protein Cross-Linking by Bis-electrophiles. Basic Clin Pharmacol Toxicol (2016) 0.75
Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med (1992) 4.82
Oxidative Nucleobase Modifications Leading to Strand Scission. Chem Rev (1998) 4.07
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature (2005) 3.67
Direct cellular responses to platinum-induced DNA damage. Chem Rev (2007) 3.42
ChIP-seq and beyond: new and improved methodologies to detect and characterize protein-DNA interactions. Nat Rev Genet (2012) 3.23
DNA binding and nucleotide flipping by the human DNA repair protein AGT. Nat Struct Mol Biol (2004) 2.86
DNA Cross-Linking Agents as Antitumor Drugs. Chem Rev (1998) 2.17
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate. EMBO J (2002) 1.87
DNA-protein crosslinks: their induction, repair, and biological consequences. Mutat Res (2005) 1.87
Biologically relevant chemical reactions of N7-alkylguanine residues in DNA. Chem Res Toxicol (2004) 1.77
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA. J Biol Chem (2002) 1.74
Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation. Proc Natl Acad Sci U S A (1992) 1.64
Covalent trapping of protein-DNA complexes. Annu Rev Biochem (2003) 1.58
Loss of DNA-protein crosslinks from formaldehyde-exposed cells occurs through spontaneous hydrolysis and an active repair process linked to proteosome function. Carcinogenesis (2000) 1.58
Repair of DNA covalently linked to protein. Mol Cell (2004) 1.52
DNA-protein cross-links in welders: molecular implications. Cancer Res (1993) 1.41
Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle. Proc Natl Acad Sci U S A (2010) 1.39
A universal method for the preparation of covalent protein-DNA conjugates for use in creating protein nanostructures. Angew Chem Int Ed Engl (2007) 1.33
Nucleotide excision repair eliminates unique DNA-protein cross-links from mammalian cells. J Biol Chem (2007) 1.31
Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools. Chem Res Toxicol (2011) 1.30
Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. J Am Chem Soc (2010) 1.28
Generation of DNA interstrand cross-links by post-synthetic reductive amination. Org Lett (2009) 1.26
Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin. Nucleic Acids Res (2007) 1.22
Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. Biochemistry (2005) 1.19
Identification of mammalian proteins cross-linked to DNA by ionizing radiation. J Biol Chem (2005) 1.18
DNA-protein cross-linking by 1,2,3,4-diepoxybutane. J Proteome Res (2010) 1.17
A DNA-dependent protease involved in DNA-protein crosslink repair. Cell (2014) 1.16
DNA-protein cross-link formation mediated by oxanine. A novel genotoxic mechanism of nitric oxide-induced DNA damage. J Biol Chem (2003) 1.16
Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes. Biochemistry (2003) 1.13
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Chem Res Toxicol (2010) 1.12
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chem Res Toxicol (2008) 1.12
Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell (2014) 1.12
Repair and biochemical effects of DNA-protein crosslinks. Mutat Res (2010) 1.12
DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells. Cancer Res (1978) 1.11
Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase. Chem Res Toxicol (2004) 1.10
Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase. J Biol Chem (2003) 1.10
DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts. J Am Chem Soc (2008) 1.07
NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite deoxyguanosine in a DNA duplex. Epsilon dA(syn).dG(anti) pairing at the lesion site. Biochemistry (1991) 1.07
Utilization of DNA-protein cross-links as a biomarker of chromium exposure. Environ Health Perspect (1998) 1.06
Cross-linking of the DNA repair protein Omicron6-alkylguanine DNA alkyltransferase to DNA in the presence of antitumor nitrogen mustards. Chem Res Toxicol (2008) 1.05
Cross-linking of the human DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence of 1,2,3,4-diepoxybutane. Chem Res Toxicol (2006) 1.05
Repair of DNA-protein cross-links in mammalian cells. Cell Cycle (2006) 1.03
Proteomic analysis of DNA-protein cross-linking by antitumor nitrogen mustards. Chem Res Toxicol (2009) 1.03
Intracellular chromium reduction. Biochim Biophys Acta (1987) 1.02
DNA-protein crosslink repair: proteases as DNA repair enzymes. Trends Biochem Sci (2014) 1.01
Mechanism of DNA-protein cross-linking by chromium. Chem Res Toxicol (2010) 1.00
The role of human O(6)-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli. Mutat Res (2000) 0.98
Mechlorethamine-induced DNA-protein cross-linking in human fibrosarcoma (HT1080) cells. J Proteome Res (2011) 0.98
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. J Am Chem Soc (2010) 0.94
DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde. Fundam Appl Toxicol (1994) 0.93
Structure and mechanism of hydroxyl radical-induced formation of a DNA-protein cross-link involving thymine and lysine in nucleohistone. Cancer Res (1989) 0.92
Age-related increases of 8-hydroxy-2'-deoxyguanosine and DNA-protein crosslinks in mouse organs. Mutat Res (1999) 0.91
DNA-reactive protein monoepoxides induce cell death and mutagenesis in mammalian cells. Biochemistry (2013) 0.90
DNA--protein crosslinks, a biomarker of exposure to formaldehyde--in vitro and in vivo studies. Carcinogenesis (1996) 0.89
1,2,3,4-Diepoxybutane-induced DNA-protein cross-linking in human fibrosarcoma (HT1080) cells. J Proteome Res (2013) 0.88
Stable DNA-protein cross-links are products of DNA charge transport in a nucleosome core particle. Biochemistry (2007) 0.88
Synthesis of site-specific DNA-protein conjugates and their effects on DNA replication. ACS Chem Biol (2014) 0.87
Alkyltransferase-mediated toxicity of 1,3-butadiene diepoxide. Chem Res Toxicol (2008) 0.87
Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI. Chem Res Toxicol (2008) 0.87
Mechanisms of the carcinogenic chromium(VI)-induced DNA-protein cross-linking and their characterization in cultured intact human cells. J Biol Chem (1996) 0.84
Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidine. J Biol Chem (2014) 0.84
Synthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy. Bioconjug Chem (2013) 0.83
DNA-protein cross-linking via guanine oxidation: dependence upon protein and photosensitizer. Biochemistry (2003) 0.83
DNA-DNA interstrand cross-linking by cis-diamminedichloroplatinum(II): N7(dG)-to-N7(dG) cross-linking at 5'-d(GC) in synthetic oligonucleotides. Bioorg Med Chem (1995) 0.80
Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction. Chem Res Toxicol (2008) 0.78