Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients.

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Published in Oncotarget on August 28, 2015

Authors

Maria Serova1,2, Annemilaï Tijeras-Raballand1,2, Célia Dos Santos1,2, Miguel Albuquerque3, Valerie Paradis3, Cindy Neuzillet2, Karim A Benhadji4, Eric Raymond2, Sandrine Faivre2,3, Armand de Gramont1,2

Author Affiliations

1: AAREC Filia Research, Boulogne-Billancourt, France.
2: INSERM U728, Department of Medical Oncology, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), Clichy, France.
3: INSERM U773, Department of Pathology, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), Clichy, France.
4: Eli Lilly and Co., Neuilly-sur-Seine, France.

Associated clinical trials:

A Study of LY2157299 in Participants With Hepatocellular Carcinoma | NCT01246986

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