Published in Cell Death Dis on June 11, 2015
P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development. Cell Death Dis (2016) 0.82
The Δ133p53 isoform and its mouse analogue Δ122p53 promote invasion and metastasis involving pro-inflammatory molecules interleukin-6 and CCL2. Oncogene (2016) 0.80
p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis? Oncotarget (2016) 0.79
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis. Cell Death Dis (2015) 0.79
Ultraconserved long non-coding RNA uc.63 in breast cancer. Oncotarget (2016) 0.76
Metabolic pathways regulated by TAp73 in response to oxidative stress. Oncotarget (2016) 0.76
p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression. Oncotarget (2016) 0.75
Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells. Cell Death Dis (2016) 0.75
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell (1997) 29.13
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature (1992) 25.54
Tumor spectrum analysis in p53-mutant mice. Curr Biol (1994) 16.60
TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell (2006) 11.85
p53 regulates mitochondrial respiration. Science (2006) 9.06
The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol (2010) 7.58
p53 isoforms can regulate p53 transcriptional activity. Genes Dev (2005) 6.76
Decision making by p53: life, death and cancer. Cell Death Differ (2003) 5.52
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell (2003) 5.13
Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer (2009) 5.06
p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products. Nat Cell Biol (2002) 2.93
p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev (2009) 2.57
p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat Cell Biol (2009) 2.46
DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53. Oncogene (2002) 2.27
The B55α subunit of PP2A drives a p53-dependent metabolic adaptation to glutamine deprivation. Mol Cell (2013) 2.24
iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53. Nat Genet (2006) 2.20
p53 polymorphic variants at codon 72 exert different effects on cell cycle progression. Int J Cancer (2004) 2.18
Structural evolution of p53, p63, and p73: implication for heterotetramer formation. Proc Natl Acad Sci U S A (2009) 1.46
The human tumour suppressor gene p53 is alternatively spliced in normal cells. Oncogene (1996) 1.27
Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Onco Targets Ther (2013) 1.27
Some p53-binding proteins that can function as arbiters of life and death. Cell Death Differ (2006) 1.25
The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression. Oncogene (2012) 1.21
p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes. J Clin Invest (2013) 1.21
Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript. FEBS Lett (2010) 1.17
The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (AMSA) series. Eur J Cancer (1974) 1.15
Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A (2012) 1.11
p53: more research and more questions. Cell Death Differ (2006) 1.08
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A (2014) 1.08
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform. Blood (2011) 1.05
p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors. Cell Death Differ (2009) 0.96
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1. Cell Cycle (2005) 0.95
Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence. Nat Commun (2014) 0.94
A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry. Cell Cycle (2010) 0.89
The role of DNA damage responses in p53 biology. Arch Toxicol (2015) 0.88
Effects of Δ40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53. BMC Cancer (2013) 0.87
Does Δ133p53 isoform trigger inflammation and autoimmunity? Cell Cycle (2012) 0.87
Ratio disruption of the ∆133p53 and TAp53 isoform equilibrium correlates with poor clinical outcome in intrahepatic cholangiocarcinoma. Int J Oncol (2013) 0.86
Activation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD). Oncogene (2012) 0.81
High-resolution cell cycle and DNA ploidy analysis in tissue samples. Curr Protoc Cytom (2011) 0.78
Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a ∆133p53α mimic. PLoS One (2015) 0.77