Published in Expert Opin Investig Drugs on June 19, 2015
Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents. J Infect Dis (2017) 0.79
Development of NanoART for HIV Treatment: Minding the Cytochrome P450 (CYP) Enzymes. J Pers Nanomed (2015) 0.75
Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase. Oncotarget (2016) 0.75
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science (2010) 35.19
Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel. JAMA (2012) 8.94
Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission. Sci Transl Med (2011) 6.79
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. AIDS Res Hum Retroviruses (2009) 4.32
Update of the drug resistance mutations in HIV-1: March 2013. Top Antivir Med (2013) 3.58
Lower pill burden and once-daily antiretroviral treatment regimens for HIV infection: A meta-analysis of randomized controlled trials. Clin Infect Dis (2014) 2.65
Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr (2009) 1.89
Long-acting injectable antiretrovirals for HIV treatment and prevention. Curr Opin HIV AIDS (2013) 1.73
Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen. J Med Virol (2001) 1.68
RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate. AIDS Res Hum Retroviruses (2012) 1.67
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proc Natl Acad Sci U S A (2015) 1.66
Pharmacokinetics of nevirapine: initial single-rising-dose study in humans. Antimicrob Agents Chemother (1993) 1.62
A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007). PLoS One (2013) 1.44
Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission. Drug Deliv Transl Res (2011) 1.44
Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS Res Hum Retroviruses (2010) 1.44
Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics. J Neuroimmune Pharmacol (2010) 1.42
Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults. J Acquir Immune Defic Syndr (2013) 1.31
Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding. Curr HIV Res (2004) 1.26
A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women. AIDS (2014) 1.25
Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice. J Infect Dis (2012) 1.23
Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections. Nanomedicine (2013) 1.21
A review of the toxicity of HIV medications. J Med Toxicol (2014) 1.19
Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates. J Med Chem (2012) 1.18
Overcoming pharmacologic sanctuaries. Curr Opin HIV AIDS (2013) 1.17
Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells. Int J Nanomedicine (2012) 1.08
Sustained-release nanoART formulation for the treatment of neuroAIDS. Int J Nanomedicine (2015) 1.07
Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study. PLoS One (2013) 1.04
Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1. Antimicrob Agents Chemother (2010) 1.03
Forty-eight-week efficacy and safety and early CNS tolerability of doravirine (MK-1439), a novel NNRTI, with TDF/FTC in ART-naive HIV-positive patients. J Int AIDS Soc (2014) 0.98
In vitro resistance selection with doravirine (MK-1439), a novel nonnucleoside reverse transcriptase inhibitor with distinct mutation development pathways. Antimicrob Agents Chemother (2014) 0.97
Efficacy and safety of lersivirine (UK-453,061) versus efavirenz in antiretroviral treatment-naive HIV-1-infected patients: week 48 primary analysis results from an ongoing, multicenter, randomized, double-blind, phase IIb trial. J Acquir Immune Defic Syndr (2013) 0.96
Phase I/II study of the pharmacokinetics, safety and antiretroviral activity of tenofovir alafenamide, a new prodrug of the HIV reverse transcriptase inhibitor tenofovir, in HIV-infected adults. J Antimicrob Chemother (2014) 0.94
Towards nanomedicines for neuroAIDS. Rev Med Virol (2014) 0.94
In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother (2013) 0.93
Future strategies in microbicide development. Best Pract Res Clin Obstet Gynaecol (2012) 0.91
Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV. Antimicrob Agents Chemother (2010) 0.90
Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems. Expert Opin Drug Metab Toxicol (2014) 0.89
Safety and tolerability of lersivirine, a nonnucleoside reverse transcriptase inhibitor, during a 28-day, randomized, placebo-controlled, Phase I clinical study in healthy male volunteers. Clin Ther (2010) 0.89
Endosomal trafficking of nanoformulated antiretroviral therapy facilitates drug particle carriage and HIV clearance. J Virol (2014) 0.88
Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorg Med Chem Lett (2009) 0.87
The antiretroviral drug pipeline: prospects and implications for future treatment research. Curr Opin HIV AIDS (2013) 0.85
Metabolism and antiretroviral activity of tenofovir alafenamide in CD4+ T-cells and macrophages from demographically diverse donors. Antivir Ther (2014) 0.84
Randomized placebo-controlled study of the safety, tolerability, antiviral activity, and pharmacokinetics of 10-day monotherapy with BMS-986001, a novel HIV NRTI, in treatment-experienced HIV-1-infected subjects. J Acquir Immune Defic Syndr (2013) 0.81
Nucleoside reverse transcriptase inhibitors in combination therapy for HIV patients: systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis (2010) 0.81
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses. Bioorg Med Chem Lett (2013) 0.80
Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1. Antiviral Res (2013) 0.80
Pharmacokinetic effects of coadministration of lersivirine with raltegravir or maraviroc in healthy subjects. Antimicrob Agents Chemother (2011) 0.79
In vitro cross-resistance profile of nucleoside reverse transcriptase inhibitor (NRTI) BMS-986001 against known NRTI resistance mutations. Antimicrob Agents Chemother (2013) 0.79
Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission. J Antimicrob Chemother (2013) 0.78
From the chemistry of epoxy-sugar nucleosides to the discovery of anti-HIV agent 4'-ethynylstavudine-Festinavir. Curr Pharm Des (2013) 0.77
Evaluation of chitosan nanoformulations as potent anti-HIV therapeutic systems. Biochim Biophys Acta (2013) 0.77
A brief review on human mtDNA mutations and NRTI-associated mtDNA toxicity and mutations. Mitochondrial DNA A DNA MappSeq Anal (2014) 0.77
Clinical use of vaginal or rectally applied microbicides in patients suffering from HIV/AIDS. HIV AIDS (Auckl) (2013) 0.77
2,4,5-Trisubstituted thiazole derivatives: a novel and potent class of non-nucleoside inhibitors of wild type and mutant HIV-1 reverse transcriptase. Eur J Med Chem (2014) 0.76
Identification of a novel sulfonamide non-nucleoside reverse transcriptase inhibitor by a phenotypic HIV-1 full replication assay. PLoS One (2013) 0.76
The pharmacokinetics of lersivirine (UK-453,061) and HIV-1 protease inhibitor coadministration in healthy subjects. J Acquir Immune Defic Syndr (2012) 0.76
Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects. Drug Des Devel Ther (2014) 0.76
Uroflowmetry in healthy women: Development and validation of flow-volume and corrected flow-age nomograms. Neurourol Urodyn (2009) 2.84
Pelvic fracture-associated urethral injuries in girls: experience with primary repair. BJU Int (2004) 1.72
Advancing the science of mHealth. J Health Commun (2012) 1.69
Retracted Ultrasonography reinvents the originally described technique for ganglion impar neurolysis in perianal cancer pain. Anesth Analg (2008) 1.58
Therapeutic efficacy of add-on yogasana intervention in stabilized outpatient schizophrenia: Randomized controlled comparison with exercise and waitlist. Indian J Psychiatry (2012) 1.55
One week of nitrofurantoin before percutaneous nephrolithotomy significantly reduces upper tract infection and urosepsis: a prospective controlled study. Urology (2010) 1.54
Arogyasree: an enhanced grid-based approach to mobile telemedicine. Int J Telemed Appl (2010) 1.53
Is there an adjunctive role of tamsulosin to extracorporeal shockwave lithotripsy for upper ureteric stones: results of an open label randomized nonplacebo controlled study. Urology (2009) 1.52
Drug compliance after stroke and myocardial infarction: a comparative study. Neurol India (2007) 1.40
Hemorrhagic cystitis: A challenge to the urologist. Indian J Urol (2010) 1.36
Barriers to yoga therapy as an add-on treatment for schizophrenia in India. Int J Yoga (2012) 1.34
Changing clinico-laboratory profile of encephalitis patients in the eastern Uttar Pradesh region of India. Trop Doct (2012) 1.31
Fracture of the penis: a radiological or clinical diagnosis? A case series and literature review. Can J Urol (2009) 1.23
Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem (2011) 1.20
Identifying Drug (Cocaine) Intake Events from Acute Physiological Response in the Presence of Free-living Physical Activity. IPSN (2014) 1.17
Optimizing the fragmentation and clearance after shock wave lithotripsy. Curr Opin Urol (2008) 1.15
Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. J Virol (2005) 1.14
Are We There Yet? Feasibility of Continuous Stress Assessment via Wireless Physiological Sensors. ACM BCB (2015) 1.12
Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4. Biochemistry (2007) 1.11
Osteopontin: a potentially important therapeutic target in cancer. Expert Opin Ther Targets (2011) 1.11
Re: Isac et al.: endoscopic-guided versus fluoroscopic-guided renal access for percutaneous nephrolithotomy: a comparative analysis (Urology 2013;81:251-256). Urology (2013) 1.08
An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryF. Biochemistry (2004) 1.07
Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model. PLoS One (2012) 1.05
Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc. Cardiovasc Res (2011) 1.04
puffMarker: A Multi-Sensor Approach for Pinpointing the Timing of First Lapse in Smoking Cessation. Proc ACM Int Conf Ubiquitous Comput (2015) 1.04
Travel time to maternity care and its effect on utilization in rural Ghana: a multilevel analysis. Soc Sci Med (2013) 1.01
Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: Report of a case diagnosed by fine needle aspiration cytology and confirmed by immunocytochemistry and RT-PCR along with review of literature. Diagn Cytopathol (2011) 1.01
Effect of alcohol on drug efflux protein and drug metabolic enzymes in U937 macrophages. Alcohol Clin Exp Res (2010) 1.01
Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. Mol Cancer (2010) 1.01
Oxidative stress and cardiac hypertrophy: a review. Toxicol Mech Methods (2012) 1.01
Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway. PLoS One (2012) 1.01
Tissue transglutaminase as a central mediator in inflammation-induced progression of breast cancer. Breast Cancer Res (2013) 1.00
Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme. Arch Biochem Biophys (2006) 1.00
Methamphetamine toxicity and its implications during HIV-1 infection. J Neurovirol (2011) 1.00
Osteopontin as a therapeutic target for cancer. Expert Opin Ther Targets (2014) 0.99
The macrophage cell surface glyceraldehyde-3-phosphate dehydrogenase is a novel transferrin receptor. J Biol Chem (2006) 0.99
HIV-1 gp120 and drugs of abuse: interactions in the central nervous system. Curr HIV Res (2012) 0.98
Microfilariae in urine. Acta Cytol (2008) 0.98
Decreased susceptibility of the cytochrome P450 2B6 variant K262R to inhibition by several clinically important drugs. Drug Metab Dispos (2008) 0.98
Urinothorax demonstrated on 99mTc ethylene dicysteine renal scintigraphy. Nephrol Dial Transplant (2007) 0.97
Overexpression of an apoplastic peroxidase gene CrPrx in transgenic hairy root lines of Catharanthus roseus. Appl Microbiol Biotechnol (2011) 0.97
Stress: Towards a Gold Standard for Continuous Stress Assessment in the Mobile Environment. Proc ACM Int Conf Ubiquitous Comput (2015) 0.97
Imaging findings in Chiari I malformation with syringomyelia in a case of charcot shoulder. J Clin Imaging Sci (2011) 0.97
Species of Gonostomum and Paragonostomum (Ciliophora, Hypotrichida, Oxytrichidae) from the Valley of Flowers, India, with descriptions of Gonostomum singhii sp nov, Paragonostomum ghangriai sp nov and Paragonostomum minuta sp nov. Indian J Microbiol (2009) 0.96
Assessing the Availability of Users to Engage in Just-in-Time Intervention in the Natural Environment. Proc ACM Int Conf Ubiquitous Comput (2015) 0.96
Isolated Malacoplakia of the bladder: a rare case report and review of literature. Int Urol Nephrol (2009) 0.95
Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrate. Biochem Biophys Res Commun (2002) 0.95
Well-being and social capital on planet earth: cross-national evidence from 142 countries. PLoS One (2012) 0.95
Surgical management of rectourethral fistula. Urology (2008) 0.94
Rifampicin-induced thrombocytopenia. Indian J Pharmacol (2010) 0.94
A LC-MS/MS method for concurrent determination of nicotine metabolites and role of CYP2A6 in nicotine metabolism in U937 macrophages: implications in oxidative stress in HIV + smokers. J Neuroimmune Pharmacol (2011) 0.94
Synergistic cooperation between methamphetamine and HIV-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes. PLoS One (2012) 0.94
Differential time-dependent inactivation of P450 3A4 and P450 3A5 by raloxifene: a key role for C239 in quenching reactive intermediates. Chem Res Toxicol (2007) 0.93
Phase transformation synthesis of novel Ag(2)O/Ag(2)CO(3) heterostructures with high visible light efficiency in photocatalytic degradation of pollutants. Adv Mater (2013) 0.93
An undiagnosed left sided traumatic diaphragmatic hernia presenting as small intestinal strangulation: A case report. Int J Surg Case Rep (2013) 0.93
Tamsulosin facilitates earlier clearance of stone fragments and reduces pain after shockwave lithotripsy for renal calculi: results from an open-label randomized study. Urology (2008) 0.93
Large but benign adrenal mass: Adrenal oncocytoma. Indian J Endocrinol Metab (2012) 0.92
Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin-induced VEGF expression. Mol Med Rep (2011) 0.92
Persistent multiple vesicocutaneous fistulas or watering-can abdomen. Urol J (2008) 0.92
Morphine and rapid disease progression in nonhuman primate model of AIDS: inverse correlation between disease progression and virus evolution. J Neuroimmune Pharmacol (2009) 0.91
Effect of environmental enrichment on methylphenidate-induced locomotion and dopamine transporter dynamics. Behav Brain Res (2011) 0.91
A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression. Hum Mol Genet (2010) 0.90
Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells. Breast Cancer Res (2012) 0.90
Urinary bladder carcinoma associated with Paget's disease of skull: Imaging findings on Tc99m-MDP bone scintigraphy, F18-Fluoride PET/CT and F18-FDG PET/CT. Indian J Nucl Med (2011) 0.89
An LC-MS/MS method for concurrent determination of nicotine metabolites and the role of CYP2A6 in nicotine metabolite-mediated oxidative stress in SVGA astrocytes. Drug Alcohol Depend (2012) 0.89
Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction. Am J Physiol Heart Circ Physiol (2012) 0.89
A nanomembrane-based wavelength-tunable high-speed single-photon-emitting diode. Nano Lett (2013) 0.89
A rare cause of hypoglycaemia. BMJ Case Rep (2009) 0.88
Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions. Drug Metab Dispos (2008) 0.88
A study on sexual function of men with anterior urethral stricture before and after treatment. Urol Int (2011) 0.88
Latzko repair for vesicovaginal fistula revisited in the era of minimal-access surgery. Int Urol Nephrol (2008) 0.88
The South Asian Heart Lifestyle Intervention (SAHELI) study to improve cardiovascular risk factors in a community setting: design and methods. Contemp Clin Trials (2013) 0.88
Evolution of variety-specific regulatory schema for expression of osa-miR408 in indica rice varieties under drought stress. FEBS J (2013) 0.87
Status of oxidative stress in patients with renal cell carcinoma. J Urol (2012) 0.87
Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes. J Biol Chem (2008) 0.87
Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide. Arch Biochem Biophys (2007) 0.87
Epitaxial quantum dots in stretchable optical microcavities. Opt Express (2009) 0.87
Plasma chromogranin A: clinical implications in patients with castrate resistant prostate cancer receiving docetaxel chemotherapy. Cancer Biomark (2011) 0.86
Polyphosphate deficiency in Mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs. J Bacteriol (2013) 0.86
Rational engineering of cytochromes P450 2B6 and 2B11 for enhanced stability: Insights into structural importance of residue 334. Arch Biochem Biophys (2009) 0.86
Which voiding position is associated with lowest flow rates in healthy adult men? role of natural voiding position. Neurourol Urodyn (2010) 0.86
Current concepts in the management of pelvic fracture urethral distraction defects. Indian J Urol (2011) 0.85
Role of PPE18 protein in intracellular survival and pathogenicity of Mycobacterium tuberculosis in mice. PLoS One (2012) 0.85
The Arabidopsis mutant, fy-1, has an ABA-insensitive germination phenotype. J Exp Bot (2012) 0.85
Tubercular mass mimicking a tumour in a horseshoe kidney: a unique presentation. Int Urol Nephrol (2004) 0.85
Visualization of Time-Series Sensor Data to Inform the Design of Just-In-Time Adaptive Stress Interventions. Proc ACM Int Conf Ubiquitous Comput (2015) 0.85
Histone and DNA methylation-mediated epigenetic downregulation of endothelial Kruppel-like factor 2 by low-density lipoprotein cholesterol. Arterioscler Thromb Vasc Biol (2013) 0.85
Identification of Late Embryogenesis Abundant (LEA) protein putative interactors using phage display. Int J Mol Sci (2012) 0.85
Redox factor-1 activates endothelial SIRTUIN1 through reduction of conserved cysteine sulfhydryls in its deacetylase domain. PLoS One (2013) 0.85
Single-stage correction of urinary incontinence and vaginoplasty in a case of urethral coitus with vaginal agenesis. Urol Int (2008) 0.85
Neuronal apoptotic signaling pathways probed and intervened by synthetically and modularly modified (SMM) chemokines. J Biol Chem (2007) 0.84
Notohymena saprai sp. nov, a new oxytrichid ciliate (Protozoa, Ciliophora) from the Valley of Flowers, a Himalayan bioreserve region; description and morphogenesis of the new species. Indian J Microbiol (2009) 0.84
Visual impairment and blindness among the students of blind schools in Allahabad and its vicinity: A causal assessment. Indian J Ophthalmol (2015) 0.84
Tuberculosis of sacrum mimicking as malignancy. BMJ Case Rep (2012) 0.83
The multifunctional glycolytic protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a novel macrophage lactoferrin receptor. Biochem Cell Biol (2012) 0.83
Toxic metals and organochlorine pesticides residue in single herbal drugs used in important ayurvedic formulation - 'Dashmoola'. Environ Monit Assess (2007) 0.83
A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent. PLoS One (2009) 0.83
A novel midline scroto-perineal approach facilitating innervation preserving sphincteroplasty and radical corporal detachment for reconstruction of exstrophy-epispadias. Urology (2011) 0.83