Published in Br J Pharmacol on July 01, 2015
Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP. Br J Pharmacol (2015) 4.46
Butein provides neuroprotective and anti-neuroinflammatory effects through Nrf2/ARE-dependent haem oxygenase 1 expression by activating the PI3K/Akt pathway. Br J Pharmacol (2016) 1.43
Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours. Br J Pharmacol (2016) 1.38
BJP is linking its articles to the IUPHAR/BPS Guide to PHARMACOLOGY. Br J Pharmacol (2015) 1.07
Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. Br J Pharmacol (2016) 0.98
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan. Br J Pharmacol (2017) 0.85
Modulation of hERG channels by 5-(((1H-indazol-5-yl)oxy)methyl)-N-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine (ITP-2), a novel small molecule activator. Br J Pharmacol (2017) 0.84
The gap junction modifier ZP1609 decreases cardiomyocyte hypercontracture following ischemia/reperfusion independent from mitochondrial connexin 43. Br J Pharmacol (2017) 0.84
Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms. Br J Pharmacol (2016) 0.83
Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist. Br J Pharmacol (2016) 0.83
Galanin inhibits GLP-1 and GIP secretion via the GAL1 receptor in enteroendocrine L and K cells. Br J Pharmacol (2016) 0.83
Ozanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity. Br J Pharmacol (2016) 0.83
Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor. Br J Pharmacol (2016) 0.82
Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels. Br J Pharmacol (2016) 0.82
The β3 -adrenoceptor agonist mirabegron increases human atrial force through β1 -adrenoceptors: an indirect mechanism? Br J Pharmacol (2017) 0.82
Pharmacological mechanisms underlying the cardiovascular effects of the "bath salt" constituent 3,4-methylenedioxypyrovalerone (MDPV). Br J Pharmacol (2016) 0.81
The acute and long-term L-DOPA effects are independent from changes in the activity of dorsal raphe serotonergic neurons in 6-OHDA lesioned rats. Br J Pharmacol (2016) 0.81
High-fat diet-induced metabolic disorders impairs 5-HT function and anxiety-like behavior in mice. Br J Pharmacol (2015) 0.81
Protection against cardiac hypertrophy by geniposide involves the GLP-1 receptor / AMPKα signalling pathway. Br J Pharmacol (2016) 0.81
The tyrosine kinase inhibitor dasatinib reduces lung inflammation and remodelling in experimental allergic asthma. Br J Pharmacol (2016) 0.81
Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release. Br J Pharmacol (2016) 0.81
Histamine H4 receptor agonist-induced relief from painful peripheral neuropathy is mediated by inhibition of spinal neuroinflammation and oxidative stress. Br J Pharmacol (2016) 0.80
PnPP-19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase. Br J Pharmacol (2016) 0.80
Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1. Br J Pharmacol (2015) 0.80
Urinary miR-155-5p and CXCL10 as prognostic and predictive biomarkers of rejection, graft outcome and treatment response in kidney transplantation. Br J Clin Pharmacol (2017) 0.80
Using the affective bias test to predict drug-induced negative affect: implications for drug safety. Br J Pharmacol (2017) 0.80
Fenofibrate inhibits atrial metabolic remodelling in atrial fibrillation through PPAR-α/sirtuin 1/PGC-1α pathway. Br J Pharmacol (2016) 0.80
Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats. Br J Pharmacol (2016) 0.79
The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue. Br J Pharmacol (2016) 0.79
Drp-1, a potential therapeutic target for brain ischaemic stroke. Br J Pharmacol (2016) 0.79
Increased mitochondrial ROS generation mediates the loss of PVAT anticontractile effect in HFD-treated obese mice. Br J Pharmacol (2016) 0.79
Adiponectin improves endothelial function in mesenteric arteries of rats fed a high-fat diet: role of perivascular adipose tissue. Br J Pharmacol (2017) 0.79
Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight. Br J Pharmacol (2017) 0.78
Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis. Br J Pharmacol (2017) 0.78
The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice. Br J Pharmacol (2016) 0.78
Alterations in pharmacological and behavioural responses in recombinant mouse line with an increased predisposition to catalepsy: role of the 5-HT1A receptor. Br J Pharmacol (2016) 0.78
Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2. Br J Pharmacol (2016) 0.78
Effects of new-generation inhibitors of the calcium-activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract. Br J Pharmacol (2016) 0.78
A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene. Br J Pharmacol (2016) 0.78
Replication - why we need to publish our findings. Pharmacol Res Perspect (2015) 0.78
Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues. Br J Pharmacol (2016) 0.78
Role of oxidative stress in oxaliplatin-induced enteric neuropathy and colonic dysmotility in mice. Br J Pharmacol (2016) 0.78
5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis. Br J Pharmacol (2016) 0.78
Non-clinical studies required for new drug development - Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies. Braz J Med Biol Res (2016) 0.78
Reporting of Preclinical Research in ANESTHESIOLOGY: Transparency and Enforcement. Anesthesiology (2016) 0.78
Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway. Br J Pharmacol (2016) 0.77
Biphasic effects of propranolol on tumour growth in B16F10 melanoma-bearing mice. Br J Pharmacol (2016) 0.77
Selective activation of vascular Kv 7.4/Kv 7.5 K(+) channels by fasudil contributes to its vasorelaxant effect. Br J Pharmacol (2016) 0.77
Key role of heat shock protein 90 in leptin-induced STAT3 activation and feeding regulation. Br J Pharmacol (2016) 0.77
Opioid and cannabinoid synergy in a mouse neuropathic pain model. Br J Pharmacol (2016) 0.77
The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model. Br J Pharmacol (2016) 0.77
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes. Br J Pharmacol (2016) 0.77
Presynaptic, release-regulating mGlu2 -preferring and mGlu3 -preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease. Br J Pharmacol (2016) 0.77
Effects of xanthine oxidase inhibition with febuxostat on the development of nephropathy in experimental type 2 diabetes. Br J Pharmacol (2016) 0.77
The anti-inflammatory effects of PGE2 on human lung macrophages are mediated by the EP4 receptor. Br J Pharmacol (2016) 0.77
An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse. Front Pharmacol (2016) 0.77
Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon. Br J Pharmacol (2016) 0.77
Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk. Br J Pharmacol (2016) 0.77
Role of COX-2-derived PGE2 on vascular stiffness and function in hypertension. Br J Pharmacol (2016) 0.77
Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis. PLoS One (2016) 0.77
Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus. Br J Pharmacol (2016) 0.77
d-Penicillamine modulates hydrogen sulfide (H2 S) pathway through selective inhibition of cystathionine-γ-lyase. Br J Pharmacol (2016) 0.77
Biased ligand quantification in drug discovery: from theory to high throughput screening to identify new biased μ opioid receptor agonists. Br J Pharmacol (2016) 0.77
Bidirectional crosstalk via IL-6, PGE2 and PGD2 between murine myofibroblasts and alternatively activated macrophages enhances anti-inflammatory phenotype in both cells. Br J Pharmacol (2016) 0.77
TRPA1 activation leads to neurogenic vasodilatation: involvement of reactive oxygen nitrogen species in addition to CGRP and NO. Br J Pharmacol (2016) 0.77
α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts. Br J Pharmacol (2016) 0.77
Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice. Br J Pharmacol (2017) 0.76
The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in dedicated goat and dog models. Br J Pharmacol (2017) 0.76
Activation of AMP-activated Protein Kinase By Metformin Ablates Angiotensin II-Induced Endoplasmic Reticulum Stress and Hypertension in Mice in vivo. Br J Pharmacol (2017) 0.76
Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain. Br J Pharmacol (2016) 0.76
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation. Br J Pharmacol (2016) 0.76
The neuropeptide cortistatin attenuates experimental autoimmune myocarditis via inhibition of cardiomyogenic T cell-driven inflammatory responses. Br J Pharmacol (2016) 0.76
Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars. Br J Pharmacol (2016) 0.76
APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model. Br J Pharmacol (2016) 0.76
Involvement of the orexin/hypocretin system in the pharmacological effects induced by Δ(9) -tetrahydrocannabinol. Br J Pharmacol (2016) 0.76
Antitumour and antiangiogenic activities of [Pt(O,O'-acac)(γ-acac)(DMS)] in a xenograft model of human renal cell carcinoma. Br J Pharmacol (2016) 0.76
Quantitative pharmacokinetic-pharmacodynamic modelling of baclofen-mediated cardiovascular effects using BP and heart rate in rats. Br J Pharmacol (2016) 0.76
Single administration of recombinant IL-6 restores the gene expression of lipogenic enzymes in liver of fasting IL-6-deficient mice. Br J Pharmacol (2016) 0.76
Effects of the imidazoline I2 receptor agonist 2-BFI on the development of tolerance to and behavioural/physical dependence on morphine in rats. Br J Pharmacol (2016) 0.76
F16357, a novel protease-activated receptor 1 antagonist, improves urodynamic parameters in a rat model of interstitial cystitis. Br J Pharmacol (2016) 0.76
Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2. Br J Pharmacol (2016) 0.76
The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced obesity in rats. Br J Pharmacol (2016) 0.76
Ap39, A Mitochondria-Targeting Hydrogen Sulfide (H2 s) Donor, Protects Against Myocardial Reperfusion Injury Independently Of Salvage Kinase Signalling. Br J Pharmacol (2016) 0.76
The metabotropic glutamate 5 receptor is necessary for extinction of cocaine-associated cues. Br J Pharmacol (2016) 0.76
Epithelial propionyl- and butyrylcholine as novel regulators of colonic ion transport. Br J Pharmacol (2016) 0.76
Anti-oxidative effect of AST-120 on kidney injury after myocardial infarction. Br J Pharmacol (2016) 0.76
Compound 9a, a novel synthetic histone deacetylase inhibitor, protects against septic injury in mice by suppressing MAPK signalling. Br J Pharmacol (2016) 0.76
Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose. Br J Pharmacol (2016) 0.76
The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. Br J Pharmacol (2016) 0.76
Therapeutic time window for angiotensin-(1-7) in acute lung injury. Br J Pharmacol (2016) 0.76
Elastase-2, an angiotensin II-generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction. Br J Pharmacol (2017) 0.76
Epidermal growth factor is a critical regulator of the cytokine IL-33 in intestinal epithelial cells. Br J Pharmacol (2016) 0.76
AQX-1125, a small molecule SHIP1 activator, inhibits bleomycin-induced pulmonary fibrosis. Br J Pharmacol (2017) 0.75
N-acetylcysteine amide (AD4) reduces cocaine-induced reinstatement. Psychopharmacology (Berl) (2016) 0.75
STAT3 Inhibition Suppresses Hepatic Stellate Cell Fibrogenesis: HJC0123, a Potential Therapeutic Agent for Liver Fibrosis. RSC Adv (2016) 0.75
Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists. Neuropharmacology (2016) 0.75
Single and combined effects of delta(9) -tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain. Br J Pharmacol (2017) 0.75
Preventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats. Br J Pharmacol (2016) 0.75
Daily morphine administration increases impulsivity in rats responding under a 5-choice serial reaction time task. Br J Pharmacol (2016) 0.75
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Design, power, and interpretation of studies in the standard murine model of ALS. Amyotroph Lateral Scler (2008) 4.05
Human basophil degranulation triggered by very dilute antiserum against IgE. Nature (1988) 4.00
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Sixteen S-squared over D-squared: a relation for crude sample size estimates. Stat Med (1992) 2.61
The fickle P value generates irreproducible results. Nat Methods (2015) 2.53
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The problem of pseudoreplication in neuroscientific studies: is it affecting your analysis? BMC Neurosci (2010) 2.13
Transparency in Research involving Animals: The Basel Declaration and new principles for reporting research in BJP manuscripts. Br J Pharmacol (2015) 1.79
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The extent and consequences of p-hacking in science. PLoS Biol (2015) 1.71
The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias. Pharmacol Ther (2013) 1.50
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Influence of blinding sequence of radiographs on the reproducibility and sensitivity to change of joint space width measurement in knee osteoarthritis. Arthritis Care Res (Hoboken) (2010) 1.23
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