Published in Br J Pharmacol on March 01, 2016
Erratum. Br J Pharmacol (2016) 0.75
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
Animal research: reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol (2010) 17.30
Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science (2000) 15.16
The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron (1998) 13.03
The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic Acids Res (2013) 9.61
Cellular and molecular mechanisms of pain. Cell (2009) 9.36
TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature (2008) 8.40
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature (2000) 7.66
The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol (2015) 5.96
A capsaicin-receptor homologue with a high threshold for noxious heat. Nature (1999) 5.85
Experimental design and analysis and their reporting: new guidance for publication in BJP. Br J Pharmacol (2015) 5.43
A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature (2007) 4.83
Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP. Br J Pharmacol (2015) 4.46
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
Cellular basis of itch sensation. Science (2009) 3.38
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A (2009) 2.96
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
Nociceptors lacking TRPV1 and TRPV2 have normal heat responses. J Neurosci (2004) 2.24
The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels. J Clin Invest (2010) 2.16
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci (2005) 2.09
Anandamide and vanilloid TRPV1 receptors. Br J Pharmacol (2003) 2.09
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. J Pharmacol Exp Ther (2004) 2.08
The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. Br J Pharmacol (2015) 1.88
Activation of TRPV1 by the satiety factor oleoylethanolamide. J Biol Chem (2003) 1.59
Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J (2011) 1.45
Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor. Sci Signal (2013) 1.29
Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons. Proc Natl Acad Sci U S A (2015) 1.24
Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain (2009) 1.24
Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh) -A01. Br J Pharmacol (2013) 1.18
Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity. Mol Pain (2014) 1.16
The biophysical and molecular basis of TRPV1 proton gating. EMBO J (2011) 1.05
Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal. J Physiol (2014) 1.02
Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. FASEB J (2014) 1.01
Distinctive changes in plasma membrane phosphoinositides underlie differential regulation of TRPV1 in nociceptive neurons. J Neurosci (2013) 0.99
The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels. Br J Pharmacol (2015) 0.98
Investigation into the mechanisms by which nedocromil sodium, frusemide and bumetanide inhibit the histamine-induced itch and flare response in human skin in vivo. Clin Exp Allergy (2004) 0.95
Epidermal growth factor chronically upregulates Ca(2+)-dependent Cl(-) conductance and TMEM16A expression in intestinal epithelial cells. J Physiol (2012) 0.94
Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells. Elife (2015) 0.93
Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16A. Proc Natl Acad Sci U S A (2015) 0.91
Anoctamin-1 Cl(-) channels in nociception: activation by an N-aroylaminothiazole and capsaicin and inhibition by T16A[inh]-A01. Mol Pain (2015) 0.87
Molecular and cellular mechanisms that initiate pain and itch. Cell Mol Life Sci (2015) 0.84
Anoctamin 1 calcium-activated chloride channel downregulates estrogen production in mouse ovarian granulosa cells. Endocrinology (2014) 0.84
9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels. Br J Pharmacol (2015) 0.84
Expression of transient receptor potential vanilloid 1 and anoctamin 1 in rat trigeminal ganglion neurons innervating the tongue. Brain Res Bull (2014) 0.83
Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity. J Clin Invest (2013) 0.83
Potassium and ANO1/ TMEM16A chloride channel profiles distinguish atypical and typical smooth muscle cells from interstitial cells in the mouse renal pelvis. Br J Pharmacol (2012) 0.80
Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats. Mol Pain (2015) 0.80
LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels. Br J Pharmacol (2014) 0.77
Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun (2017) 0.75