Published in Development on July 02, 2015
Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model. PLoS One (2015) 0.84
Merkel cells are long-lived cells whose production is stimulated by skin injury. Dev Biol (2016) 0.75
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet (2016) 0.75
Merkel cell polyomavirus small T antigen initiates Merkel cell carcinoma-like tumor development in mice. Cancer Res (2017) 0.75
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc Natl Acad Sci U S A (1999) 7.67
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science (2001) 7.17
Math1: an essential gene for the generation of inner ear hair cells. Science (1999) 5.49
Sonic hedgehog regulates growth and morphogenesis of the tooth. Development (2000) 4.71
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int Immunol (2002) 4.66
Lighting up the senses: FM1-43 loading of sensory cells through nonselective ion channels. J Neurosci (2003) 4.28
Math1 is essential for genesis of cerebellar granule neurons. Nature (1997) 4.16
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res (2005) 4.08
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci (2000) 3.88
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development (2000) 2.94
Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron (2005) 2.93
The functional organization of cutaneous low-threshold mechanosensory neurons. Cell (2011) 2.83
Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells. Cell Stem Cell (2009) 2.45
Piezo2 is required for Merkel-cell mechanotransduction. Nature (2014) 2.45
Merkel cells are essential for light-touch responses. Science (2009) 2.24
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature (2014) 2.24
Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol (2009) 2.24
Merkel cells transduce and encode tactile stimuli to drive Aβ-afferent impulses. Cell (2014) 2.14
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J Neurosci (2001) 2.07
Hes1 is a negative regulator of inner ear hair cell differentiation. Development (2000) 1.85
Molecular profiling reveals synaptic release machinery in Merkel cells. Proc Natl Acad Sci U S A (2004) 1.77
Atonal homolog 1 is a tumor suppressor gene. PLoS Biol (2009) 1.76
Wounding mobilizes hair follicle stem cells to form tumors. Proc Natl Acad Sci U S A (2011) 1.68
Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches. Cell Stem Cell (2015) 1.66
Eccrine and squamous differentiation in Merkel cell carcinoma. An immunohistochemical study. Am J Surg Pathol (1988) 1.64
Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med (Berl) (2005) 1.61
Mammalian Merkel cells are descended from the epidermal lineage. Dev Biol (2009) 1.58
Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles. J Neurosci (2011) 1.53
Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns (2007) 1.52
Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo. J Neurosci (2012) 1.43
Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate. Dev Biol (2010) 1.41
Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Dev Biol (1997) 1.40
Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice. J Assoc Res Otolaryngol (2000) 1.38
Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells. EMBO J (2013) 1.33
Identification of Merkel cells in human skin by specific cytokeratin antibodies: changes of cell density and distribution in fetal and adult plantar epidermis. Differentiation (1984) 1.31
Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression. J Biol Chem (2011) 1.24
Notch signaling in bulge stem cells is not required for selection of hair follicle fate. Development (2009) 1.23
Merkel cell and squamous cell carcinomas arising in erythema ab igne. Br J Dermatol (1993) 1.22
The Notch signalling pathway in hair growth. Mech Dev (1998) 1.21
Rodents rely on Merkel cells for texture discrimination tasks. J Neurosci (2012) 1.19
Dynamics of Merkel cell patterns in developing hair follicles in the dorsal skin of mice, demonstrated by a monoclonal antibody to mouse keratin 8. Acta Anat (Basel) (1995) 1.15
Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin. J Neurosci (2012) 1.13
Cytokeratin 20 is a general marker of cutaneous Merkel cells while certain neuronal proteins are absent. J Invest Dermatol (1995) 1.06
Patterning in the regeneration of type I cutaneous receptors. J Physiol (1974) 1.05
Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice. J Invest Dermatol (2014) 1.03
Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol (2013) 1.03
Merkel cells in mouse skin: intermediate filament pattern, localization, and hair cycle-dependent density. J Invest Dermatol (1996) 1.02
The touch dome defines an epidermal niche specialized for mechanosensory signaling. Cell Rep (2013) 1.01
Diverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC. Development (2002) 1.00
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma. Int J Cancer (2002) 0.97
Mixed Merkel cell carcinoma and squamous cell carcinoma of the skin. J Am Acad Dermatol (1998) 0.97
Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice. J Cell Biol (2015) 0.96
Expression of Reg IV and Hath1 in neuroendocrine neoplasms. Histol Histopathol (2010) 0.94
A new role for neurotrophin-3: involvement in the regulation of hair follicle regression (catagen). Am J Pathol (1998) 0.94
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development (2010) 0.93
Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn (2000) 0.93
A new role for neurotrophins: involvement of brain-derived neurotrophic factor and neurotrophin-4 in hair cycle control. FASEB J (1999) 0.93
Expression of Notch-1 and alteration of the E-cadherin/beta-catenin cell adhesion complex are observed in primary cutaneous neuroendocrine carcinoma (Merkel cell carcinoma). Mod Pathol (2009) 0.92
Early B-cell differentiation in Merkel cell carcinomas: clues to cellular ancestry. Cancer Res (2013) 0.92
Relationship between Merkel cells and nerve endings during embryogenesis in the mouse epidermis. J Invest Dermatol (1990) 0.92
Changes in the number of Merkel cells with the hair cycle in hair discs on rat back skin. Br J Dermatol (2006) 0.90
Immunohistochemical localization of vasoactive intestinal polypeptide (VIP) in Merkel cells of various mammals: evidence for a neuromodulator function of the Merkel cell. J Invest Dermatol (1983) 0.89
Met enkephalin-like immunoreactivity in Merkel cells. Cell Tissue Res (1979) 0.88
Effects of chronic denervation in type I cutaneous mechanoreceptors (Haarscheiben). Anat Rec (1983) 0.87
Neurochemical markers in human cutaneous Merkel cells. An immunohistochemical investigation. Exp Dermatol (1995) 0.87
Calcitonin gene-related peptide (CGRP) immunoreactivity in the neuroendocrine Merkel cells and nerve fibres of pig and human skin. Histochemistry (1989) 0.86
Anatomical projections of the nuclei of the lateral lemniscus in the albino rat (Rattus norvegicus). J Comp Neurol (2009) 0.86
Serotonin-like immunoreactivity in Merkel cells and their afferent neurons in touch domes from the hairy skin of rats. Anat Rec (1992) 0.85
Ontogeny of the cutaneous sensory organs. Microsc Res Tech (1996) 0.84
Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network. Development (2014) 0.84
Neurotrophin-3 involvement in the regulation of hair follicle morphogenesis. J Invest Dermatol (1998) 0.83
Pancreastatin-like immunoreactivity in epidermal Merkel cells of pig and man. Neurosci Lett (1989) 0.82
Immunocytochemical evidence of a met-enkephalin-like substance in the dense-core granules of mouse Merkel cells. Cell Tissue Res (1991) 0.81
Merkel cells in lower vertebrates. Arch Histol Cytol (1989) 0.81
Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol (2000) 0.78
Immunohistochemical analysis of chromogranin A and multiple peptides in the mammalian Merkel cell: further evidence for its paraneuronal function? Arch Histol Cytol (1989) 0.78
Immunocytochemical analysis of calcitonin gene-related peptide and vasoactive intestinal polypeptide in Merkel cells and cutaneous free nerve endings of cats. Cell Tissue Res (1988) 0.78
Presence of putative stem cells in Merkel cell carcinomas. J Eur Acad Dermatol Venereol (2011) 0.78
Evidence of turnover of mammalian Merkel cells. J Anat (1987) 0.77
Merkel cell carcinoma. Adv Dermatol (2003) 0.76
Neuroendocrine (Merkel cell) carcinoma of the skin: a clinico-morphological study of 13 cases. Histopathology (1989) 0.76