Published in Am J Med Genet B Neuropsychiatr Genet on July 14, 2015
Expanding the toolbox of ADHD genetics. How can we make sense of parent of origin effects in ADHD and related behavioral phenotypes? Behav Brain Funct (2015) 0.75
Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders. Sci Rep (2017) 0.75
Regulation of tyrosine hydroxylase is preserved across different homo- and heterodimeric 14-3-3 proteins. Amino Acids (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
The International HapMap Project. Nature (2003) 73.65
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics (2003) 17.92
Biological insights from 108 schizophrenia-associated genetic loci. Nature (2014) 16.13
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet (2013) 13.17
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet (2011) 7.80
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
De novo mutations in schizophrenia implicate synaptic networks. Nature (2014) 6.59
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science (2003) 4.58
The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci (2003) 3.79
Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications. JAMA (2005) 3.74
SNPassoc: an R package to perform whole genome association studies. Bioinformatics (2007) 3.52
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 3.13
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Genome-wide association studies in ADHD. Hum Genet (2009) 2.58
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet (2008) 2.53
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. J Neural Transm (Vienna) (2008) 2.43
14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet (2003) 2.27
Structural basis for protein-protein interactions in the 14-3-3 protein family. Proc Natl Acad Sci U S A (2006) 1.95
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia. Mol Psychiatry (2011) 1.86
Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Neuropsychopharmacology (2006) 1.83
Maternal serotonin is crucial for murine embryonic development. Proc Natl Acad Sci U S A (2006) 1.75
The genetics of attention deficit/hyperactivity disorder in adults, a review. Mol Psychiatry (2011) 1.46
Molecular genetics of attention-deficit/hyperactivity disorder: an overview. Eur Child Adolesc Psychiatry (2010) 1.45
A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters. Mol Neurobiol (2009) 1.45
Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder. Am J Psychiatry (2011) 1.38
The molecular genetics of executive function: role of monoamine system genes. Biol Psychiatry (2011) 1.36
Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology (2009) 1.33
Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment. J Med Genet (2009) 1.31
DISC1-binding proteins in neural development, signalling and schizophrenia. Neuropharmacology (2010) 1.27
Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Hum Mol Genet (2008) 1.23
Mutations in human monoamine-related neurotransmitter pathway genes. Hum Mutat (2008) 1.19
Occupational outcome in adult ADHD: impact of symptom profile, comorbid psychiatric problems, and treatment: a cross-sectional study of 414 clinically diagnosed adult ADHD patients. J Atten Disord (2009) 1.18
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. Am J Med Genet B Neuropsychiatr Genet (2013) 1.11
Genetic analyses of dopamine related genes in adult ADHD patients suggest an association with the DRD5-microsatellite repeat, but not with DRD4 or SLC6A3 VNTRs. Am J Med Genet B Neuropsychiatr Genet (2008) 1.10
14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria. J Biol Chem (2009) 1.09
14-3-3 proteins in neurological disorders. Int J Biochem Mol Biol (2012) 1.05
Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. Genes Brain Behav (2007) 1.04
Regulation of tyrosine hydroxylase by stress-activated protein kinases. J Neurochem (2002) 1.03
The heritability of clinically diagnosed attention deficit hyperactivity disorder across the lifespan. Psychol Med (2013) 0.99
Different properties of the central and peripheral forms of human tryptophan hydroxylase. J Neurochem (2005) 0.99
Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins. Biochemistry (1999) 0.96
Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochem J (2008) 0.93
Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production. Arch Gen Psychiatry (2010) 0.92
TPH2 gene polymorphisms and major depression--a meta-analysis. PLoS One (2012) 0.91
Epigenetic, transcriptional and posttranscriptional regulation of the tyrosine hydroxylase gene. Int J Dev Neurosci (2011) 0.89
Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3γ. Mol Cell Proteomics (2014) 0.88
The polymorphism of YWHAE, a gene encoding 14-3-3epsilon, and orbitofrontal sulcogyral pattern in patients with schizophrenia and healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry (2014) 0.86
Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins. J Biol Chem (1997) 0.86
Genome-wide copy number variation analysis in adult attention-deficit and hyperactivity disorder. J Psychiatr Res (2013) 0.83
DISC1 in adult ADHD patients: an association study in two European samples. Am J Med Genet B Neuropsychiatr Genet (2013) 0.82
Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations. Am J Med Genet B Neuropsychiatr Genet (2010) 0.81
Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction. Transl Psychiatry (2013) 0.80
Polymorphisms and haplotypes in the YWHAE gene increase susceptibility to bipolar disorder in Chinese Han population. J Clin Psychiatry (2012) 0.80
Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities. PLoS One (2013) 0.79
Association with tryptophan hydroxylase 2 gene polymorphisms and autism spectrum disorders in Korean families. Neurosci Res (2012) 0.79
The role of serotonergic genes and environmental stress on the development of depressive symptoms and neuroticism. J Affect Disord (2012) 0.79
Neurocognitive problems in attention deficit disorder. Alternative concepts and evidence for impairment in inhibition of selective attention. Ann N Y Acad Sci (2001) 0.79
Epistasis between neurochemical gene polymorphisms and risk for ADHD. Eur J Hum Genet (2011) 0.79
Functional gene-set analysis does not support a major role for synaptic function in attention deficit/hyperactivity disorder (ADHD). Genes (Basel) (2014) 0.78
No association of the YWHAE gene with schizophrenia, major depressive disorder or bipolar disorder in the Han Chinese population. Behav Genet (2010) 0.77
A two-stage case-control association study between the tryptophan hydroxylase 2 (TPH2) gene and schizophrenia in a Japanese population. Schizophr Res (2012) 0.77