PubRank

Martin Eilers

Author PubWeight™ 110.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002 13.92
2 Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005 7.54
3 Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell 2009 3.92
4 The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol 2007 3.63
5 Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002 2.99
6 The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation. Cell 2005 2.85
7 Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. Blood 2009 2.82
8 MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer 2008 2.76
9 Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene 2003 2.59
10 Transcriptional repression by Myc. Trends Cell Biol 2003 2.19
11 Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J 2004 2.19
12 The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol Cell 2011 2.17
13 Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature 2012 1.88
14 The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance. Genes Dev 2010 1.81
15 p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci U S A 2010 1.77
16 Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol 2006 1.65
17 Contributions of Myc to tumorigenesis. Biochim Biophys Acta 2002 1.63
18 Facilitating replication under stress: an oncogenic function of MYC? Nat Rev Cancer 2009 1.56
19 DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2010 1.47
20 A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth. Nat Cell Biol 2008 1.46
21 Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell 2002 1.44
22 FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. Genes Dev 2007 1.43
23 Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover. Nat Cell Biol 2010 1.39
24 Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1. EMBO J 2008 1.36
25 Transcriptional repression: the dark side of myc. Genes Cancer 2010 1.34
26 A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF. Cancer Res 2010 1.29
27 Miz1 is required for early embryonic development during gastrulation. Mol Cell Biol 2003 1.29
28 Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle 2007 1.26
29 Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage. Nat Cell Biol 2004 1.25
30 Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation. EMBO J 2008 1.23
31 Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood 2003 1.22
32 Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation. Immunity 2010 1.21
33 The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol 2010 1.16
34 Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation. J Biol Chem 2010 1.15
35 Myc increases self-renewal in neural progenitor cells through Miz-1. J Cell Sci 2008 1.12
36 Miz1 is required to maintain autophagic flux. Nat Commun 2013 1.12
37 C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma. Int J Cancer 2007 1.11
38 The role of MIZ-1 in MYC-dependent tumorigenesis. Cold Spring Harb Perspect Med 2013 1.10
39 Miz1 is required for hair follicle structure and hair morphogenesis. J Cell Sci 2007 1.09
40 Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nat Immunol 2013 1.08
41 Selective ablation of retinoblastoma protein function by the RET finger protein. Mol Cell 2005 1.05
42 Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1. Mech Dev 2005 1.04
43 Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes. Oncogene 2005 1.02
44 Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leukemia cells in response to chemotherapy. PLoS One 2009 1.01
45 The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer. J Clin Invest 2014 1.00
46 Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6. J Biol Chem 2005 0.99
47 Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1. J Biol Chem 2003 0.98
48 Control of cell proliferation and growth by Myc proteins. Results Probl Cell Differ 2006 0.96
49 PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity. FEBS Lett 2011 0.95
50 Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors. PLoS Genet 2012 0.94
51 All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo. Oncogene 2005 0.92
52 CIP2A influences survival in colon cancer and is critical for maintaining Myc expression. PLoS One 2013 0.91
53 Identification of a novel Krüppel-associated box domain protein, Krim-1, that interacts with c-Myc and inhibits its oncogenic activity. J Biol Chem 2003 0.91
54 Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation. Proc Natl Acad Sci U S A 2009 0.90
55 Miz1 is a critical repressor of cdkn1a during skin tumorigenesis. PLoS One 2012 0.90
56 Loss of caspase-8 expression does not correlate with MYCN amplification, aggressive disease, or prognosis in neuroblastoma. Cancer Res 2006 0.89
57 Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2. J Biol Chem 2005 0.87
58 DeltaNp73 can modulate the expression of various genes in a p53-independent fashion. Oncogene 2003 0.87
59 Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins. BMC Cancer 2010 0.86
60 HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53. DNA Repair (Amst) 2009 0.84
61 PIM1 and MYC: a changing relationship? Nat Cell Biol 2007 0.81
62 An unsteady scaffold for Myc. EMBO J 2009 0.81
63 The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1. Virology 2011 0.80
64 TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas. Cell Cycle 2010 0.78
65 Addicted to Myc--but why? Genes Dev 2011 0.78
66 ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure. Circ Cardiovasc Genet 2015 0.75
67 Pluripotency without Max. Cell Stem Cell 2011 0.75
68 Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma. Cancer Cell 2016 0.75
69 The first Sino-German Symposium on DNA Repair and Human Diseases. DNA Repair (Amst) 2011 0.75