Published in Immunity on December 14, 2010
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles. Nature (2014) 2.33
Bcl11a is essential for lymphoid development and negatively regulates p53. J Exp Med (2012) 1.51
The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity. Cancer Cell (2016) 1.47
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15. Genes Dev (2013) 1.30
The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity. J Exp Med (2014) 1.21
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling. Nat Rev Immunol (2013) 1.18
POK/ZBTB proteins: an emerging family of proteins that regulate lymphoid development and function. Immunol Rev (2012) 1.14
Miz1 is required to maintain autophagic flux. Nat Commun (2013) 1.12
The role of MIZ-1 in MYC-dependent tumorigenesis. Cold Spring Harb Perspect Med (2013) 1.10
Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia. Blood (2015) 1.08
Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nat Immunol (2013) 1.08
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 1.04
Transcriptional control of early T and B cell developmental choices. Annu Rev Immunol (2014) 1.03
The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function. Immunol Rev (2014) 1.02
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
The BTB-ZF transcription factors. Cell Cycle (2012) 0.93
ZBTB1 is a determinant of lymphoid development. J Exp Med (2011) 0.91
Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombination. Proc Natl Acad Sci U S A (2014) 0.91
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis. PLoS One (2012) 0.90
Transcription factor networks directing the development, function, and evolution of innate lymphoid effectors. Annu Rev Immunol (2015) 0.87
Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function. Stem Cells Int (2015) 0.84
Miz-1 activates gene expression via a novel consensus DNA binding motif. PLoS One (2014) 0.82
Late onset neuropathy with spontaneous clinical remission in mice lacking the POZ domain of the transcription factor Myc-interacting zinc finger protein 1 (Miz1) in Schwann cells. J Biol Chem (2014) 0.81
STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis. JAKSTAT (2013) 0.80
Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors. J Immunol (2016) 0.78
Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene (2015) 0.78
Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells. Sci Rep (2016) 0.78
Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation. PLoS One (2014) 0.77
Nac1 interacts with the POZ-domain transcription factor, Miz1. Biosci Rep (2014) 0.76
Decreased MIZ1 Expression in Severe Experimental Acute Pancreatitis: A Rat Study. Dig Dis Sci (2015) 0.76
A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish. Sci Rep (2017) 0.75
Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1. PLoS One (2016) 0.75
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis. Am J Blood Res (2014) 0.75
Structures of heterodimeric POZ domains of Miz1/BCL6 and Miz1/NAC1. Acta Crystallogr F Struct Biol Commun (2014) 0.75
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell (2002) 13.92
Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol (2005) 7.54
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell (2009) 3.92
The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol (2007) 3.63
Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell (2002) 2.99
Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nat Genet (2002) 2.87
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation. Cell (2005) 2.85
Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. Blood (2009) 2.82
MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer (2008) 2.76
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene (2003) 2.59
Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J (2004) 2.57
The serine/threonine kinase Pim-1. Int J Biochem Cell Biol (2005) 2.32
Transcriptional repression by Myc. Trends Cell Biol (2003) 2.19
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J (2004) 2.19
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol Cell (2011) 2.17
The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus. J Exp Med (2003) 1.96
Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature (2012) 1.88
The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance. Genes Dev (2010) 1.81
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci U S A (2010) 1.77
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene. Hum Mol Genet (2004) 1.73
Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol (2006) 1.65
Contributions of Myc to tumorigenesis. Biochim Biophys Acta (2002) 1.63
Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells. J Immunol (2005) 1.57
Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development. J Biol Chem (2004) 1.56
Facilitating replication under stress: an oncogenic function of MYC? Nat Rev Cancer (2009) 1.56
The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C. Int J Biochem Cell Biol (2005) 1.50
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell (2010) 1.47
A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth. Nat Cell Biol (2008) 1.46
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell (2002) 1.44
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin. EMBO J (2006) 1.44
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. Genes Dev (2007) 1.43
Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover. Nat Cell Biol (2010) 1.39
Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1. EMBO J (2008) 1.36
Transcriptional repression: the dark side of myc. Genes Cancer (2010) 1.34
The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint. J Biol Chem (2004) 1.32
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF. Cancer Res (2010) 1.29
Miz1 is required for early embryonic development during gastrulation. Mol Cell Biol (2003) 1.29
High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells. Oncogene (2002) 1.26
Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle (2007) 1.26
Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage. Nat Cell Biol (2004) 1.25
Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation. EMBO J (2008) 1.23
Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood (2003) 1.22
The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function. Immunity (2005) 1.22
Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep (2006) 1.21
Nuclear interaction of the dynein light chain LC8a with the TRPS1 transcription factor suppresses the transcriptional repression activity of TRPS1. Hum Mol Genet (2003) 1.17
Identification of Tcf-4 as a transcriptional target of p53 signalling. Oncogene (2004) 1.16
The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol (2010) 1.16
Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation. J Biol Chem (2010) 1.15
Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia. Dev Biol (2008) 1.13
Myc increases self-renewal in neural progenitor cells through Miz-1. J Cell Sci (2008) 1.12
Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Res (2005) 1.12
Miz1 is required to maintain autophagic flux. Nat Commun (2013) 1.12
C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma. Int J Cancer (2007) 1.11
The role of MIZ-1 in MYC-dependent tumorigenesis. Cold Spring Harb Perspect Med (2013) 1.10
Origin of the brush cell lineage in the mouse intestinal epithelium. Dev Biol (2011) 1.09
Miz1 is required for hair follicle structure and hair morphogenesis. J Cell Sci (2007) 1.09
GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment. Blood (2012) 1.08
Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nat Immunol (2013) 1.08
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease. Stem Cells (2011) 1.07
Selective ablation of retinoblastoma protein function by the RET finger protein. Mol Cell (2005) 1.05
New indene-derivatives with anti-proliferative properties. Bioorg Med Chem Lett (2002) 1.05
Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1. Mech Dev (2005) 1.04
Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood (2006) 1.04
Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes. Oncogene (2005) 1.02
Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leukemia cells in response to chemotherapy. PLoS One (2009) 1.01
Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia. Blood (2002) 1.00
The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer. J Clin Invest (2014) 1.00
Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6. J Biol Chem (2005) 0.99
The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor. J Biol Chem (2003) 0.99
Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia. Int J Hematol (2009) 0.99
Gfi1 negatively regulates T(h)17 differentiation by inhibiting RORgammat activity. Int Immunol (2009) 0.98
The MHC class II beta chain cytoplasmic tail overcomes the invariant chain p35-encoded endoplasmic reticulum retention signal. Int Immunol (2003) 0.98
IL-7R-dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1. Blood (2011) 0.98
Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1. J Biol Chem (2003) 0.98
Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing. Nat Immunol (2006) 0.97
Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening. Angew Chem Int Ed Engl (2004) 0.96
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia. Blood (2010) 0.96
Control of cell proliferation and growth by Myc proteins. Results Probl Cell Differ (2006) 0.96
PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity. FEBS Lett (2011) 0.95
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice. Blood (2012) 0.95
Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells. Blood (2010) 0.94
Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors. PLoS Genet (2012) 0.94
Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation. FEBS J (2005) 0.93
Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells. J Immunol (2012) 0.92
All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo. Oncogene (2005) 0.92
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. Cancer Cell (2013) 0.91
Systemic lupus-erythematosus: deoxyribonuclease 1 in necrotic chromatin disposal. Int J Biochem Cell Biol (2005) 0.91
CIP2A influences survival in colon cancer and is critical for maintaining Myc expression. PLoS One (2013) 0.91
Identification of a novel Krüppel-associated box domain protein, Krim-1, that interacts with c-Myc and inhibits its oncogenic activity. J Biol Chem (2003) 0.91
Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function. Eur J Immunol (2007) 0.91
Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation. Proc Natl Acad Sci U S A (2009) 0.90