Published in CPT Pharmacometrics Syst Pharmacol on February 26, 2015
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Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network. Front Aging Neurosci (2017) 0.75
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Cooperative binding mitigates the high-dose hook effect. BMC Syst Biol (2017) 0.75
Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Elife (2017) 0.75
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Modeling the interactions between osteoblast and osteoclast activities in bone remodeling. J Theor Biol (2004) 1.77
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The impact of mathematical modeling on the understanding of diabetes and related complications. CPT Pharmacometrics Syst Pharmacol (2013) 1.12
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neurosci Lett (2007) 1.08
Modelling the actions of chaperones and their role in ageing. Mech Ageing Dev (2005) 1.07
Retrieval, alignment, and clustering of computational models based on semantic annotations. Mol Syst Biol (2011) 0.99
Qualitative translation of relations from BioPAX to SBML qual. Bioinformatics (2012) 0.98
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An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline. BMC Syst Biol (2007) 0.91
Modelling the role of the Hsp70/Hsp90 system in the maintenance of protein homeostasis. PLoS One (2011) 0.91
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A C library for retrieving specific reactions from the BioModels database. Bioinformatics (2013) 0.85
Computational model of EGFR and IGF1R pathways in lung cancer: a Systems Biology approach for Translational Oncology. Biotechnol Adv (2011) 0.84
Systems pharmacology models can be used to understand complex pharmacokinetic-pharmacodynamic behavior: an example using 5-lipoxygenase inhibitors. CPT Pharmacometrics Syst Pharmacol (2013) 0.83
Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer's disease: a stochastic modelling approach. Mol Neurodegener (2012) 0.82
Modelling the role of UCH-L1 on protein aggregation in age-related neurodegeneration. PLoS One (2010) 0.82
A multiscale model of interleukin-6-mediated immune regulation in Crohn's disease and its application in drug discovery and development. CPT Pharmacometrics Syst Pharmacol (2014) 0.81
Experimental and computational analysis of polyglutamine-mediated cytotoxicity. PLoS Comput Biol (2010) 0.80
Effects of IL-1β-Blocking Therapies in Type 2 Diabetes Mellitus: A Quantitative Systems Pharmacology Modeling Approach to Explore Underlying Mechanisms. CPT Pharmacometrics Syst Pharmacol (2014) 0.78
Investigating interventions in Alzheimer's disease with computer simulation models. PLoS One (2013) 0.77