Published in Nat Protoc on July 30, 2015
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants. Nat Commun (2016) 0.77
Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption. Sci Rep (2016) 0.76
A method to customize population-specific arrays for genome-wide association testing. Eur J Hum Genet (2016) 0.75
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet (2017) 0.75
Inclusion of Population-specific Reference Panel from India to the 1000 Genomes Phase 3 Panel Improves Imputation Accuracy. Sci Rep (2017) 0.75
Genome-Wide Linkage Analysis of Large Multiple Multigenerational Families Identifies Novel Genetic Loci for Coronary Artery Disease. Sci Rep (2017) 0.75
Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nat Genet (2014) 4.33
Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet (2016) 1.90
Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. J Am Coll Cardiol (2016) 1.68
Genome-wide patterns and properties of de novo mutations in humans. Nat Genet (2015) 1.65
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet (2015) 1.55
Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. Eur J Hum Genet (2014) 1.41
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma. Nat Genet (2014) 1.41
The impact of low-frequency and rare variants on lipid levels. Nat Genet (2015) 1.20
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet (2016) 1.20
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet (2014) 1.13
Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency. PLoS Genet (2013) 1.10
Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease. Nat Genet (2015) 1.09
Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nat Genet (2014) 1.04
Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. PLoS Genet (2015) 0.94
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun (2015) 0.93
Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates. Am J Hum Genet (2015) 0.91
Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia. Alzheimers Dement (2015) 0.87
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nat Methods (2014) 0.86
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes (2015) 0.86
Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes. Ann Neurol (2015) 0.84
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. PLoS One (2014) 0.79
Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset. Behav Genet (2015) 0.78
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants. Nat Commun (2016) 0.77
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Hum Mol Genet (2017) 0.76
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet (2017) 0.75
The factor structure of dental fear. Eur J Oral Sci (2017) 0.75
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Diabetes (2017) 0.75
Negative selection in humans and fruit flies involves synergistic epistasis. Science (2017) 0.75