Published in Mol Ther on July 31, 2015
The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation. J Neuroinflammation (2016) 0.79
Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer's Disease. J Neuroimmune Pharmacol (2016) 0.75
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science (2002) 49.51
A specific amyloid-beta protein assembly in the brain impairs memory. Nature (2006) 16.19
Alzheimer's disease: the amyloid cascade hypothesis. Science (1992) 13.80
The molecular pathology of Alzheimer's disease. Neuron (1991) 8.21
Tricine-SDS-PAGE. Nat Protoc (2006) 7.89
Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci (2007) 5.72
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem (2001) 4.51
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging (2003) 3.83
Alzheimer's disease: strategies for disease modification. Nat Rev Drug Discov (2010) 3.48
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques. Neurology (1988) 3.28
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Hum Gene Ther (2007) 2.64
Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med (2012) 2.56
Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci (2008) 2.01
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis. J Neurosci (2010) 1.93
Cell-surface CD74 initiates a signaling cascade leading to cell proliferation and survival. Blood (2006) 1.89
Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease. Acta Neuropathol (2010) 1.80
Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells. J Neurosci Res (2004) 1.55
Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience (2006) 1.53
Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain. Gene Ther (2003) 1.50
Immunotherapy for Alzheimer's disease. J Intern Med (2011) 1.43
Membrane trafficking pathways in Alzheimer's disease. Traffic (2012) 1.39
Immunotherapy for Alzheimer's disease: hoops and hurdles. Mol Neurodegener (2013) 1.35
Abeta oligomer-mediated long-term potentiation impairment involves protein phosphatase 1-dependent mechanisms. J Neurosci (2007) 1.28
A CD74-dependent MHC class I endolysosomal cross-presentation pathway. Nat Immunol (2012) 1.23
CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract. World J Gastroenterol (2009) 1.10
Pharmacological strategies for the prevention of Alzheimer's disease. Expert Opin Pharmacother (2006) 1.02
FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders. Proc Natl Acad Sci U S A (2011) 1.00
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Mol Neurodegener (2008) 1.00
Amyloid precursor protein-processing products affect mononuclear phagocyte activation: pathways for sAPP- and Abeta-mediated neurotoxicity. J Neurochem (2003) 0.98
The secret second life of an innocent chaperone: the story of CD74 and B cell/chronic lymphocytic leukemia cell survival. Leuk Lymphoma (2011) 0.96
Is there still any hope for amyloid-based immunotherapy for Alzheimer's disease? Curr Opin Psychiatry (2014) 0.96
Endothelin-converting enzymes degrade intracellular β-amyloid produced within the endosomal/lysosomal pathway and autophagosomes. J Biol Chem (2013) 0.93
Deposition of amyloid beta protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of beta protein in neurodegenerative disease. Acta Neuropathol (1992) 0.91
A model of nitric oxide induced α-synuclein misfolding in Parkinson's disease. Neurosci Lett (2012) 0.83
Rottlerin and curcumin: a comparative analysis. Ann N Y Acad Sci (2012) 0.82
CD74 interacts with APP and suppresses the production of Abeta. Mol Neurodegener (2009) 0.80