Published in Lab Chip on September 21, 2015
Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science (2006) 4.12
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat Mater (2012) 4.10
Extracellular-matrix tethering regulates stem-cell fate. Nat Mater (2012) 3.94
Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J Cell Biol (2006) 3.37
Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells. Nat Mater (2014) 2.09
Role of the extracellular matrix in regulating stem cell fate. Nat Rev Mol Cell Biol (2013) 2.09
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proc Natl Acad Sci U S A (2009) 1.89
A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials (2004) 1.84
Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve. PLoS One (2012) 1.54
Molding of three-dimensional microstructures of gels. J Am Chem Soc (2003) 1.53
How deeply cells feel: methods for thin gels. J Phys Condens Matter (2010) 1.51
Water-soluble sacrificial layers for surface micromachining. Small (2005) 1.16
Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D. Integr Biol (Camb) (2013) 1.09
A polydimethylsiloxane (PDMS) sponge for the selective absorption of oil from water. ACS Appl Mater Interfaces (2011) 1.05
(Micro)managing the mechanical microenvironment. Integr Biol (Camb) (2011) 1.04
Control of stem cell fate and function by engineering physical microenvironments. Integr Biol (Camb) (2012) 1.04
Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2012) 1.04
Fabrication of substrates with defined mechanical properties and topographical features for the study of cell migration. Macromol Biosci (2011) 0.99
Biochemical and mechanical environment cooperatively regulate skeletal muscle regeneration. FASEB J (2012) 0.98
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. Biomaterials (2014) 0.96
Necking and failure of constrained 3D microtissues induced by cellular tension. Proc Natl Acad Sci U S A (2013) 0.96
Controlling matrix stiffness and topography for the study of tumor cell migration. Cell Adh Migr (2012) 0.95
UV-modulated substrate rigidity for multiscale study of mechanoresponsive cellular behaviors. Langmuir (2012) 0.87
Microstructured templates for directed growth and vascularization of soft tissue in vivo. Biomaterials (2011) 0.87
Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. Biomaterials (2014) 0.86
Aqueous two-phase printing of cell-containing contractile collagen microgels. Biomaterials (2013) 0.84
Micropatterning of hydrogels by soft embossing. Langmuir (2009) 0.83
Hydrogel substrate stiffness and topography interact to induce contact guidance in cardiac fibroblasts. Macromol Biosci (2012) 0.81
The glass transition temperatures of sugar mixtures. Carbohydr Res (2006) 0.79
Ultra-soft PDMS-based magnetoactive elastomers as dynamic cell culture substrata. PLoS One (2013) 0.78
Impact of caramelization on the glass transition temperature of several caramelized sugars. Part I: Chemical analyses. J Agric Food Chem (2008) 0.78
Crystallization inhibition of an amorphous sucrose system using raffinose. J Zhejiang Univ Sci B (2006) 0.77
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. Analyst (2010) 2.56
Computerized microfluidic cell culture using elastomeric channels and Braille displays. Proc Natl Acad Sci U S A (2004) 2.51
Is acupuncture safe? A systematic review of case reports. Altern Ther Health Med (2003) 2.41
Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy. J Control Release (2012) 2.12
Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification. Anal Chem (2007) 2.10
Fabrication of reconfigurable protein matrices by cracking. Nat Mater (2005) 2.08
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems. Proc Natl Acad Sci U S A (2007) 2.02
Microfluidics for flow cytometric analysis of cells and particles. Physiol Meas (2005) 2.00
Tuneable elastomeric nanochannels for nanofluidic manipulation. Nat Mater (2007) 1.96
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PLoS One (2009) 1.87
Cell shape and substrate rigidity both regulate cell stiffness. Biophys J (2011) 1.86
Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Dev Cell (2002) 1.74
Computer-controlled microcirculatory support system for endothelial cell culture and shearing. Anal Chem (2005) 1.70
Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nat Protoc (2011) 1.60
Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annu Rev Biophys (2012) 1.55
Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture. Biomed Microdevices (2007) 1.55
Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids. Biomaterials (2009) 1.54
How vinculin regulates force transmission. Proc Natl Acad Sci U S A (2013) 1.51
Integrated Elastomeric Components for Autonomous Regulation of Sequential and Oscillatory Flow Switching in Microfluidic Devices. Nat Phys (2010) 1.49
Passively driven integrated microfluidic system for separation of motile sperm. Anal Chem (2003) 1.48
Nanotopography influences adhesion, spreading, and self-renewal of human embryonic stem cells. ACS Nano (2012) 1.47
Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices. Anal Chem (2007) 1.45
Instantaneous fabrication of arrays of normally closed, adjustable, and reversible nanochannels by tunnel cracking. Lab Chip (2010) 1.45
Molecular sieving using nanofilters: past, present and future. Lab Chip (2007) 1.40
Leakage-free bonding of porous membranes into layered microfluidic array systems. Anal Chem (2007) 1.39
Efficient formation of uniform-sized embryoid bodies using a compartmentalized microchannel device. Lab Chip (2007) 1.36
Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLoS Pathog (2008) 1.34
Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids. Integr Biol (Camb) (2009) 1.33
Hard top soft bottom microfluidic devices for cell culture and chemical analysis. Anal Chem (2009) 1.32
Organs-on-a-chip: a focus on compartmentalized microdevices. Ann Biomed Eng (2011) 1.25
Mechanics regulates fate decisions of human embryonic stem cells. PLoS One (2012) 1.24
On being the right size: scaling effects in designing a human-on-a-chip. Integr Biol (Camb) (2013) 1.23
Flexible fabrication and applications of polymer nanochannels and nanoslits. Chem Soc Rev (2011) 1.20
The mechanical properties of a surface-modified layer on poly(dimethylsiloxane). J Mater Res (2008) 1.19
DNA linearization through confinement in nanofluidic channels. Anal Bioanal Chem (2008) 1.18
Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs. Biomaterials (2009) 1.18
Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells. Integr Biol (Camb) (2010) 1.17
Nanoscale squeezing in elastomeric nanochannels for single chromatin linearization. Nano Lett (2012) 1.16
Guided fracture of films on soft substrates to create micro/nano-feature arrays with controlled periodicity. Sci Rep (2013) 1.16
Polymeric aqueous biphasic systems for non-contact cell printing on cells: engineering heterocellular embryonic stem cell niches. Adv Mater (2010) 1.15
384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids. Biotechnol Bioeng (2011) 1.15
A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response. Lab Chip (2011) 1.13
The effect of continuous wavy micropatterns on silicone substrates on the alignment of skeletal muscle myoblasts and myotubes. Biomaterials (2006) 1.13
Adhesion strength-based, label-free isolation of human pluripotent stem cells. Nat Methods (2013) 1.12
Quantitative analysis of molecular absorption into PDMS microfluidic channels. Ann Biomed Eng (2012) 1.12
Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model. Lab Chip (2010) 1.11
Constant flow-driven microfluidic oscillator for different duty cycles. Anal Chem (2011) 1.11
External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos. Dev Cell (2013) 1.10
Next-generation integrated microfluidic circuits. Lab Chip (2011) 1.09
Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies. ACS Nano (2012) 1.08
Phase-locked signals elucidate circuit architecture of an oscillatory pathway. PLoS Comput Biol (2010) 1.07
Microfluidic blood cell sorting: now and beyond. Small (2014) 1.07
Individually programmable cell stretching microwell arrays actuated by a Braille display. Biomaterials (2008) 1.06
Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation. Analyst (2004) 1.06
An integrated microfluidic platform for in situ cellular cytokine secretion immunophenotyping. Lab Chip (2012) 1.06
Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes. Lab Chip (2014) 1.05
The art of reporter proteins in science: past, present and future applications. BMB Rep (2010) 1.04
Fabrication of microfluidic mixers and artificial vasculatures using a high-brightness diode-pumped Nd:YAG laser direct write method. Lab Chip (2003) 1.04
Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip (2005) 1.03
Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture. J Biomed Opt (2006) 1.02
IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm. Hum Reprod (2005) 1.01
Microfluidic culture of single human embryonic stem cell colonies. Lab Chip (2009) 1.00
Rethinking in vitro embryo culture: new developments in culture platforms and potential to improve assisted reproductive technologies. Biol Reprod (2012) 1.00
Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves. Lab Chip (2010) 0.99
Isolation of motile spermatozoa from semen samples using microfluidics. Reprod Biomed Online (2003) 0.99
Microfluidic applications for andrology. J Androl (2005) 0.99
Reversible on-demand cell alignment using reconfigurable microtopography. Biomaterials (2008) 0.97
Synergistic regulation of cell function by matrix rigidity and adhesive pattern. Biomaterials (2011) 0.96
Micro- and nanotechnologies for studying cellular function. Curr Top Med Chem (2003) 0.96
Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change. J Am Chem Soc (2003) 0.95
A cost-effective fluorescence mini-microscope for biomedical applications. Lab Chip (2015) 0.95
Unsteady propagation of a liquid plug in a liquid-lined straight tube. Phys Fluids (1994) (2008) 0.95
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J (2012) 0.95
Photolithographic surface micromachining of polydimethylsiloxane (PDMS). Lab Chip (2011) 0.95
Liquid and surfactant delivery into pulmonary airways. Respir Physiol Neurobiol (2008) 0.93
Microprinted feeder cells guide embryonic stem cell fate. Biotechnol Bioeng (2011) 0.93
Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems. Integr Biol (Camb) (2010) 0.93
Elastomeric microposts integrated into microfluidics for flow-mediated endothelial mechanotransduction analysis. Lab Chip (2012) 0.92
Acoustic tweezing cytometry for live-cell subcellular modulation of intracellular cytoskeleton contractility. Sci Rep (2013) 0.92
Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates. Biomed Microdevices (2012) 0.92
Integrated nanoplasmonic sensing for cellular functional immunoanalysis using human blood. ACS Nano (2014) 0.91
Precisely targeted delivery of cells and biomolecules within microchannels using aqueous two-phase systems. Biomed Microdevices (2011) 0.91
Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics. Lab Chip (2011) 0.90
Live-cell subcellular measurement of cell stiffness using a microengineered stretchable micropost array membrane. Integr Biol (Camb) (2012) 0.90
Super-resolution imaging of PDMS nanochannels by single-molecule micelle-assisted blink microscopy. J Phys Chem B (2013) 0.90
Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies. Adv Funct Mater (2011) 0.89
Quantitative inference of cellular parameters from microfluidic cell culture systems. Biotechnol Bioeng (2009) 0.89
Single cell trapping in larger microwells capable of supporting cell spreading and proliferation. Microfluid Nanofluidics (2010) 0.89
Hi-Fi transmission of periodic signals amid cell-to-cell variability. Mol Biosyst (2011) 0.89
Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers. Anal Chem (2010) 0.88
Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns. Lab Chip (2014) 0.88
UV-modulated substrate rigidity for multiscale study of mechanoresponsive cellular behaviors. Langmuir (2012) 0.87
Micropatterning bacterial suspensions using aqueous two phase systems. Analyst (2010) 0.87
Transwells with microstamped membranes produce micropatterned two-dimensional and three-dimensional co-cultures. Tissue Eng Part C Methods (2010) 0.87
Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model. Biomed Microdevices (2011) 0.87
Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device. Biomed Microdevices (2010) 0.87
Emerging microfluidic tools for functional cellular immunophenotyping: a new potential paradigm for immune status characterization. Front Oncol (2013) 0.87
A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development. Zebrafish (2009) 0.86
Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes. Adv Healthc Mater (2013) 0.86