Published in Diabetes on August 07, 2015
Look AHEAD: Action for Health in Diabetes (LookAHEAD) | NCT00017953
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Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med (2010) 8.77
Genetic studies of body mass index yield new insights for obesity biology. Nature (2015) 8.27
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Baseline characteristics of the randomised cohort from the Look AHEAD (Action for Health in Diabetes) study. Diab Vasc Dis Res (2006) 4.30
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Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program. Diabetologia (2008) 1.27
Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr (2012) 1.18
The genetics of obesity. Curr Diab Rep (2010) 1.11
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FTO predicts weight regain in the Look AHEAD clinical trial. Int J Obes (Lond) (2013) 0.88
Mitochondrial translation initiation factor 3 polymorphism and Parkinson's disease. Neurosci Lett (2010) 0.85
Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered (2013) 0.84
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
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Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes (2011) 2.21
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet (2009) 2.09
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet (2012) 1.84
Common body mass index-associated variants confer risk of extreme obesity. Hum Mol Genet (2009) 1.69
CRTC3 links catecholamine signalling to energy balance. Nature (2010) 1.55
Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes. PLoS Genet (2012) 1.31
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet (2013) 1.23
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet (2016) 1.22
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Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet (2013) 0.94
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet (2014) 0.93
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Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity. Hum Mol Genet (2015) 0.85
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet (2013) 0.84
Mendelian randomization study of height and risk of colorectal cancer. Int J Epidemiol (2015) 0.83
Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity. Am J Med Genet B Neuropsychiatr Genet (2014) 0.81
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1. Diabetologia (2011) 0.78
Testing the role of predicted gene knockouts in human anthropometric trait variation. Hum Mol Genet (2016) 0.77
Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants. Diabetes (2015) 0.77
Environmental rather than genetic factors determine the variation in the age of the infancy to childhood transition: a twins study. J Pediatr (2015) 0.77
How US Smokers Refer to E-cigarettes: An Examination of User-Generated Posts From a Web-Based Smoking Cessation Intervention, 2008-2015. Nicotine Tob Res (2016) 0.75
Physical Function Following a Long-Term Lifestyle Intervention among Middle Aged and Older Adults with Type 2 Diabetes: the Look AHEAD Study. J Gerontol A Biol Sci Med Sci (2017) 0.75
Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLoS Genet (2017) 0.75
H. pylori seroprevalence and risk of diabetes: An ancillary case-control study nested in the diabetes prevention program. J Diabetes Complications (2017) 0.75
Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care (2017) 0.75
Using Genotype-Based Recall to Estimate the Effects of AMY1 Copy Number Variation in Substrate Metabolism. Diabetes (2016) 0.75