Published in Curr Opin Struct Biol on August 06, 2015
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Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases. PLoS Comput Biol (2016) 0.79
Distributions of experimental protein structures on coarse-grained free energy landscapes. J Chem Phys (2015) 0.78
An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology. Cell Discov (2016) 0.78
Molecular determinants of cadherin ideal bond formation: Conformation-dependent unbinding on a multidimensional landscape. Proc Natl Acad Sci U S A (2016) 0.75
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Effect of Dimerization on the Dynamics of Neurotransmitter:Sodium Symporters. J Phys Chem B (2017) 0.75
Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling. J Mol Biol (2017) 0.75
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Protein dynamism and evolvability. Science (2009) 3.57
Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state. Proc Natl Acad Sci U S A (2005) 2.84
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Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information. Elife (2014) 2.23
The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding. Proc Natl Acad Sci U S A (2009) 2.12
Close correspondence between the motions from principal component analysis of multiple HIV-1 protease structures and elastic network modes. Structure (2008) 1.76
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function. Proc Natl Acad Sci U S A (2013) 1.75
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Structural landscape of isolated agonist-binding domains from single AMPA receptors. Nat Chem Biol (2011) 1.49
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An analysis of core deformations in protein superfamilies. Biophys J (2004) 1.33
MetaPSICOV: combining coevolution methods for accurate prediction of contacts and long range hydrogen bonding in proteins. Bioinformatics (2014) 1.26
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Deciphering the deformation modes associated with function retention and specialization in members of the Ras superfamily. Structure (2010) 1.11
Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins. Protein Sci (2011) 1.09
Exploring the common dynamics of homologous proteins. Application to the globin family. Biophys J (2005) 1.08
Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states. Curr Biol (2014) 1.07
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CO₂directly modulates connexin 26 by formation of carbamate bridges between subunits. Elife (2013) 1.05
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The robustness and innovability of protein folds. Curr Opin Struct Biol (2014) 0.99
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Parallel dynamics and evolution: Protein conformational fluctuations and assembly reflect evolutionary changes in sequence and structure. Bioessays (2013) 0.93
Effects of N-glycosylation on protein conformation and dynamics: Protein Data Bank analysis and molecular dynamics simulation study. Sci Rep (2015) 0.93
Computational approaches to mapping allosteric pathways. Curr Opin Struct Biol (2014) 0.91
Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB. PLoS Comput Biol (2012) 0.91
Accuracy-rate tradeoffs: how do enzymes meet demands of selectivity and catalytic efficiency? Curr Opin Chem Biol (2014) 0.90
Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science (2014) 0.90
How does KCNE1 regulate the Kv7.1 potassium channel? Model-structure, mutations, and dynamics of the Kv7.1-KCNE1 complex. Structure (2012) 0.88
ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones. PLoS Comput Biol (2014) 0.88
Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters. J Biol Chem (2015) 0.87
Elastic Network Models are Robust to Variations in Formalism. J Chem Theory Comput (2012) 0.87
Structural and dynamics aspects of ASC speck assembly. Structure (2014) 0.86
Comparing the intrinsic dynamics of multiple protein structures using elastic network models. Biochim Biophys Acta (2014) 0.85
Protein flexibility facilitates quaternary structure assembly and evolution. PLoS Biol (2014) 0.84
Non-interacting surface solvation and dynamics in protein-protein interactions. Proteins (2015) 0.83
Extracellular-regulated kinase 2 is activated by the enhancement of hinge flexibility. J Mol Biol (2014) 0.82
Global low-frequency motions in protein allostery: CAP as a model system. Biophys Rev (2015) 0.82
Conformational state distributions and catalytically relevant dynamics of a hinge-bending enzyme studied by single-molecule FRET and a coarse-grained simulation. Biophys J (2014) 0.81
Druggable orthosteric and allosteric hot spots to target protein-protein interactions. Curr Pharm Des (2014) 0.81
Evidence of conformational selection driving the formation of ligand binding sites in protein-protein interfaces. PLoS Comput Biol (2014) 0.81
Molecular evolution of protein conformational changes revealed by a network of evolutionarily coupled residues. Mol Biol Evol (2011) 0.81
Comparative study of the effectiveness and limitations of current methods for detecting sequence coevolution. Bioinformatics (2015) 0.80
Conformational dynamics of nonsynonymous variants at protein interfaces reveals disease association. Proteins (2015) 0.80
Elastic network normal mode dynamics reveal the GPCR activation mechanism. Proteins (2013) 0.80
Structural basis for Na(+)-sensitivity in dopamine D2 and D3 receptors. Chem Commun (Camb) (2015) 0.79
Features of large hinge-bending conformational transitions. Prediction of closed structure from open state. Biophys J (2014) 0.79
WebPSN: a web server for high-throughput investigation of structural communication in biomacromolecules. Bioinformatics (2014) 0.77
Allosteric inhibition of the neuropeptidase neurolysin. J Biol Chem (2014) 0.77
Drug-resistant HIV-1 protease regains functional dynamics through cleavage site coevolution. Evol Appl (2015) 0.77
Structure-based network analysis of an evolved G protein-coupled receptor homodimer interface. Protein Sci (2013) 0.76
Dynamics differentiate between active and inactive inteins. Eur J Med Chem (2014) 0.76
Dynamic fluctuations provide the basis of a conformational switch mechanism in apo cyclic AMP receptor protein. PLoS Comput Biol (2013) 0.76
On the packing density of the unbound protein-protein interaction interface and its implications in dynamics. BMC Bioinformatics (2015) 0.76
Molecular dynamics studies of the protein-protein interactions in inhibitor of κB kinase-β. J Chem Inf Model (2014) 0.76
Allostery through protein-induced DNA bubbles. Sci Rep (2015) 0.76
Molecular investigations into the mechanics of a muscle anchoring complex. Biophys J (2015) 0.76
Binding affinities controlled by shifting conformational equilibria: opportunities and limitations. Biophys J (2015) 0.75