Published in Proc Natl Acad Sci U S A on November 21, 2011
Protein 3D structure computed from evolutionary sequence variation. PLoS One (2011) 4.71
Three-dimensional structures of membrane proteins from genomic sequencing. Cell (2012) 3.02
Emerging methods in protein co-evolution. Nat Rev Genet (2013) 2.72
Protein structure prediction from sequence variation. Nat Biotechnol (2012) 2.50
Assessing the utility of coevolution-based residue-residue contact predictions in a sequence- and structure-rich era. Proc Natl Acad Sci U S A (2013) 2.43
Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information. Elife (2014) 2.23
Network deconvolution as a general method to distinguish direct dependencies in networks. Nat Biotechnol (2013) 2.05
Accurate de novo structure prediction of large transmembrane protein domains using fragment-assembly and correlated mutation analysis. Proc Natl Acad Sci U S A (2012) 2.02
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. Chem Soc Rev (2015) 1.74
Genomics-aided structure prediction. Proc Natl Acad Sci U S A (2012) 1.63
Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis. Proc Natl Acad Sci U S A (2012) 1.57
Sequence co-evolution gives 3D contacts and structures of protein complexes. Elife (2014) 1.55
Should evolutionary geneticists worry about higher-order epistasis? Curr Opin Genet Dev (2013) 1.52
Mutation effects predicted from sequence co-variation. Nat Biotechnol (2017) 1.47
Protein structure determination using metagenome sequence data. Science (2017) 1.47
Integrated analysis of residue coevolution and protein structures capture key protein sectors in HIV-1 proteins. PLoS One (2015) 1.42
Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism. BMC Genomics (2016) 1.41
Detection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated server. BMC Bioinformatics (2016) 1.39
Coevolution Analysis of HIV-1 Envelope Glycoprotein Complex. PLoS One (2015) 1.39
RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures. RNA (2015) 1.30
FreeContact: fast and free software for protein contact prediction from residue co-evolution. BMC Bioinformatics (2014) 1.20
Improved contact predictions using the recognition of protein like contact patterns. PLoS Comput Biol (2014) 1.16
Coevolutionary signals across protein lineages help capture multiple protein conformations. Proc Natl Acad Sci U S A (2013) 1.14
Large-scale determination of previously unsolved protein structures using evolutionary information. Elife (2015) 1.14
Predicting protein contact map using evolutionary and physical constraints by integer programming. Bioinformatics (2013) 1.13
PconsFold: improved contact predictions improve protein models. Bioinformatics (2014) 1.12
Evaluation of residue-residue contact prediction in CASP10. Proteins (2013) 1.10
Protein modeling: what happened to the "protein structure gap"? Structure (2013) 1.08
Biophysics of protein evolution and evolutionary protein biophysics. J R Soc Interface (2014) 1.08
Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1. Mol Biol Evol (2015) 1.05
From principal component to direct coupling analysis of coevolution in proteins: low-eigenvalue modes are needed for structure prediction. PLoS Comput Biol (2013) 1.03
Causes of evolutionary rate variation among protein sites. Nat Rev Genet (2016) 1.03
Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information. Proc Natl Acad Sci U S A (2014) 1.03
The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing. PLoS Comput Biol (2014) 1.02
Evolutionary imprint of activation: the design principles of VSDs. J Gen Physiol (2014) 1.02
Computational protein design quantifies structural constraints on amino acid covariation. PLoS Comput Biol (2013) 0.99
Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1. Proc Natl Acad Sci U S A (2014) 0.98
Improving contact prediction along three dimensions. PLoS Comput Biol (2014) 0.98
One contact for every twelve residues allows robust and accurate topology-level protein structure modeling. Proteins (2013) 0.97
Fast and accurate multivariate Gaussian modeling of protein families: predicting residue contacts and protein-interaction partners. PLoS One (2014) 0.97
Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity. Nat Immunol (2016) 0.96
Dynamic architecture of a protein kinase. Proc Natl Acad Sci U S A (2014) 0.94
Evolution, energy landscapes and the paradoxes of protein folding. Biochimie (2014) 0.94
Combining experiments and simulations using the maximum entropy principle. PLoS Comput Biol (2014) 0.92
Protein sector analysis for the clustering of disease-associated mutations. BMC Genomics (2014) 0.92
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs. Chem Rev (2016) 0.92
From residue coevolution to protein conformational ensembles and functional dynamics. Proc Natl Acad Sci U S A (2015) 0.92
Critical assessment of methods of protein structure prediction: Progress and new directions in round XI. Proteins (2016) 0.91
Covariation Is a Poor Measure of Molecular Coevolution. Mol Biol Evol (2015) 0.90
Correlated electrostatic mutations provide a reservoir of stability in HIV protease. PLoS Comput Biol (2012) 0.90
Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity. Structure (2015) 0.89
Quantitative modeling of virus evolutionary dynamics and adaptation in serial passages using empirically inferred fitness landscapes. J Virol (2013) 0.89
Global quantitative modeling of chromatin factor interactions. PLoS Comput Biol (2014) 0.89
Epistasis in protein evolution. Protein Sci (2016) 0.88
ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones. PLoS Comput Biol (2014) 0.88
New encouraging developments in contact prediction: Assessment of the CASP11 results. Proteins (2015) 0.87
Multidimensional mutual information methods for the analysis of covariation in multiple sequence alignments. BMC Bioinformatics (2014) 0.87
Prediction of contact residue pairs based on co-substitution between sites in protein structures. PLoS One (2013) 0.87
Mining tertiary structural motifs for assessment of designability. Methods Enzymol (2013) 0.87
Capturing coevolutionary signals inrepeat proteins. BMC Bioinformatics (2015) 0.86
Predicting functionally informative mutations in Escherichia coli BamA using evolutionary covariance analysis. Genetics (2013) 0.86
Dimeric interactions and complex formation using direct coevolutionary couplings. Sci Rep (2015) 0.86
Protein structure determination by combining sparse NMR data with evolutionary couplings. Nat Methods (2015) 0.86
Inferring interaction partners from protein sequences. Proc Natl Acad Sci U S A (2016) 0.85
Inter-Protein Sequence Co-Evolution Predicts Known Physical Interactions in Bacterial Ribosomes and the Trp Operon. PLoS One (2016) 0.85
Statistical analyses of protein sequence alignments identify structures and mechanisms in signal activation of sensor histidine kinases. Mol Microbiol (2012) 0.84
Inferring Pairwise Interactions from Biological Data Using Maximum-Entropy Probability Models. PLoS Comput Biol (2015) 0.84
Inferring Contacting Residues within and between Proteins: What Do the Probabilities Mean? PLoS Comput Biol (2016) 0.84
Protein sectors: statistical coupling analysis versus conservation. PLoS Comput Biol (2015) 0.84
Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems. Proc Natl Acad Sci U S A (2012) 0.84
Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy. Nat Commun (2015) 0.83
Structured States of Disordered Proteins from Genomic Sequences. Cell (2016) 0.83
A small set of succinct signature patterns distinguishes Chinese and non-Chinese HIV-1 genomes. PLoS One (2013) 0.83
Large-Scale Conformational Transitions and Dimerization Are Encoded in the Amino-Acid Sequences of Hsp70 Chaperones. PLoS Comput Biol (2015) 0.83
A general pairwise interaction model provides an accurate description of in vivo transcription factor binding sites. PLoS One (2014) 0.83
DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment. BMC Bioinformatics (2015) 0.83
Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio (2014) 0.83
Adaptability of protein structures to enable functional interactions and evolutionary implications. Curr Opin Struct Biol (2015) 0.82
Structure-Encoded Global Motions and Their Role in Mediating Protein-Substrate Interactions. Biophys J (2015) 0.82
3D RNA and Functional Interactions from Evolutionary Couplings. Cell (2016) 0.82
Constructing sequence-dependent protein models using coevolutionary information. Protein Sci (2015) 0.82
Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens. PLoS One (2015) 0.82
All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences. Proc Natl Acad Sci U S A (2015) 0.81
Accurate Estimation of the Intrinsic Dimension Using Graph Distances: Unraveling the Geometric Complexity of Datasets. Sci Rep (2016) 0.81
Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models. PLoS Comput Biol (2016) 0.81
Comparative sequence analysis suggests a conserved gating mechanism for TRP channels. J Gen Physiol (2015) 0.81
Progress and challenges in predicting protein interfaces. Brief Bioinform (2015) 0.81
CoeViz: a web-based tool for coevolution analysis of protein residues. BMC Bioinformatics (2016) 0.81
Accurate De Novo Prediction of Protein Contact Map by Ultra-Deep Learning Model. PLoS Comput Biol (2017) 0.81
Accurate contact predictions using covariation techniques and machine learning. Proteins (2015) 0.80
Recent advances in functional region prediction by using structural and evolutionary information - Remaining problems and future extensions. Comput Struct Biotechnol J (2013) 0.80
Comparative study of the effectiveness and limitations of current methods for detecting sequence coevolution. Bioinformatics (2015) 0.80
I-COMS: Interprotein-COrrelated Mutations Server. Nucleic Acids Res (2015) 0.80
A new ensemble coevolution system for detecting HIV-1 protein coevolution. Biol Direct (2015) 0.80
Prediction and redesign of protein-protein interactions. Prog Biophys Mol Biol (2014) 0.80
Ultra-large alignments using phylogeny-aware profiles. Genome Biol (2015) 0.80
The Maximum Entropy Fallacy Redux? PLoS Comput Biol (2016) 0.80
The Context-Dependence of Mutations: A Linkage of Formalisms. PLoS Comput Biol (2016) 0.80
Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics. F1000Res (2016) 0.80
Molecular replacement: tricks and treats. Acta Crystallogr D Biol Crystallogr (2013) 0.80
The Protein Data Bank. Nucleic Acids Res (2000) 187.10
Profile hidden Markov models. Bioinformatics (1998) 56.04
The Pfam protein families database. Nucleic Acids Res (2009) 37.98
The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata. Nucleic Acids Res (2009) 9.98
Evolutionarily conserved pathways of energetic connectivity in protein families. Science (1999) 9.12
Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis. EMBO J (1990) 6.51
Two-component and phosphorelay signal transduction. Curr Opin Microbiol (2000) 5.70
Correlated mutations and residue contacts in proteins. Proteins (1994) 5.20
Rewiring the specificity of two-component signal transduction systems. Cell (2008) 4.80
Identification of direct residue contacts in protein-protein interaction by message passing. Proc Natl Acad Sci U S A (2008) 4.37
Protein sectors: evolutionary units of three-dimensional structure. Cell (2009) 3.76
Medium- and long-range interaction parameters between amino acids for predicting three-dimensional structures of proteins. Macromolecules (1977) 3.53
Mutual information without the influence of phylogeny or entropy dramatically improves residue contact prediction. Bioinformatics (2007) 3.42
Correlations among amino acid sites in bHLH protein domains: an information theoretic analysis. Mol Biol Evol (2000) 2.81
Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa. J Biol Chem (2004) 2.74
Influence of conservation on calculations of amino acid covariance in multiple sequence alignments. Proteins (2004) 2.62
Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol Cell (2003) 2.50
Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains. Genes Dev (2003) 2.50
How frequent are correlated changes in families of protein sequences? Proc Natl Acad Sci U S A (1994) 2.41
Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations? Protein Eng (1994) 2.30
Correlation of co-ordinated amino acid substitutions with function in viruses related to tobacco mosaic virus. J Mol Biol (1987) 2.28
The MiST2 database: a comprehensive genomics resource on microbial signal transduction. Nucleic Acids Res (2009) 2.25
Dimerization allows DNA target site recognition by the NarL response regulator. Nat Struct Biol (2002) 2.05
Disentangling direct from indirect co-evolution of residues in protein alignments. PLoS Comput Biol (2010) 1.98
Using multiple interdependency to separate functional from phylogenetic correlations in protein alignments. Bioinformatics (2003) 1.84
Respective roles of short- and long-range interactions in protein folding. Proc Natl Acad Sci U S A (1978) 1.81
Separation of phylogenetic and functional associations in biological sequences by using the parametric bootstrap. Proc Natl Acad Sci U S A (2000) 1.65
High-resolution protein complexes from integrating genomic information with molecular simulation. Proc Natl Acad Sci U S A (2009) 1.57
Features of protein-protein interactions in two-component signaling deduced from genomic libraries. Methods Enzymol (2007) 1.54
Determination of network of residues that regulate allostery in protein families using sequence analysis. Protein Sci (2006) 1.35
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid representation. Algorithms Mol Biol (2007) 1.25
Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation. J Mol Biol (2008) 1.20
Dissecting the specificity of protein-protein interaction in bacterial two-component signaling: orphans and crosstalks. PLoS One (2011) 1.20
The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat Struct Biol (1996) 1.15
Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase. Biochemistry (2005) 1.12
Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA. Biochemistry (2004) 1.08
Comparison of anionic and cationic trypsinogens: the anionic activation domain is more flexible in solution and differs in its mode of BPTI binding in the crystal structure. Protein Sci (1999) 1.03
Inference of direct residue contacts in two-component signaling. Methods Enzymol (2010) 1.00
Computational modeling of phosphotransfer complexes in two-component signaling. Methods Enzymol (2010) 0.97
On the accuracy of inferring energetic coupling between distant sites in protein families from evolutionary imprints: illustrations using lattice model. Proteins (2009) 0.93
Long- and short-range interactions in native protein structures are consistent/minimally frustrated in sequence space. Proteins (2003) 0.90
Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family. J Mol Biol (2007) 0.86
Amyloids go genomic: insights regarding the sequence determinants of prion formation from genome-wide studies. Chembiochem (2009) 0.82
Human MicroRNA targets. PLoS Biol (2004) 34.51
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
Integration of biological networks and gene expression data using Cytoscape. Nat Protoc (2007) 27.10
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov (2012) 26.98
Integrative genomic profiling of human prostate cancer. Cancer Cell (2010) 23.61
MicroRNA targets in Drosophila. Genome Biol (2003) 23.59
Global mapping of the yeast genetic interaction network. Science (2004) 21.34
International network of cancer genome projects. Nature (2010) 20.35
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal (2013) 19.54
The microRNA.org resource: targets and expression. Nucleic Acids Res (2007) 16.26
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
Characterizing gene sets with FuncAssociate. Bioinformatics (2003) 14.10
Identification of microRNAs of the herpesvirus family. Nat Methods (2005) 12.98
Identification of virus-encoded microRNAs. Science (2004) 12.56
The somatic genomic landscape of glioblastoma. Cell (2013) 11.73
The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet (2013) 11.29
Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res (2011) 10.99
The BioPAX community standard for pathway data sharing. Nat Biotechnol (2010) 9.19
Pathway Commons, a web resource for biological pathway data. Nucleic Acids Res (2010) 9.18
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
The Systems Biology Graphical Notation. Nat Biotechnol (2009) 8.53
Mutual exclusivity analysis identifies oncogenic network modules. Genome Res (2011) 7.22
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol (2010) 7.15
Cellular cofactors affecting hepatitis C virus infection and replication. Proc Natl Acad Sci U S A (2007) 6.79
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. Proc Natl Acad Sci U S A (2009) 6.78
Genome sequencing identifies a basis for everolimus sensitivity. Science (2012) 6.71
Emerging landscape of oncogenic signatures across human cancers. Nat Genet (2013) 6.48
miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol (2004) 6.44
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet (2010) 6.10
Pathguide: a pathway resource list. Nucleic Acids Res (2006) 6.05
On schemes of combinatorial transcription logic. Proc Natl Acad Sci U S A (2003) 6.02
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat Genet (2009) 5.31
Transcriptional regulation by the numbers: models. Curr Opin Genet Dev (2005) 5.20
Interdependence of cell growth and gene expression: origins and consequences. Science (2010) 5.00
MicroRNA profiling of the murine hematopoietic system. Genome Biol (2005) 4.94
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence. Genome Biol (2008) 4.78
Protein 3D structure computed from evolutionary sequence variation. PLoS One (2011) 4.71
Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. Genes Dev (2009) 4.43
Identification of direct residue contacts in protein-protein interaction by message passing. Proc Natl Acad Sci U S A (2008) 4.37
Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun (2013) 4.35
Functional copy-number alterations in cancer. PLoS One (2008) 4.27
Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell (2005) 3.95
Protein folding mediated by solvation: water expulsion and formation of the hydrophobic core occur after the structural collapse. Proc Natl Acad Sci U S A (2002) 3.78
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol (2009) 3.66
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood (2007) 3.64
Automated network analysis identifies core pathways in glioblastoma. PLoS One (2010) 3.64
A series of PDB related databases for everyday needs. Nucleic Acids Res (2010) 3.60
Growth rate-dependent global effects on gene expression in bacteria. Cell (2009) 3.57
Determinants of protein function revealed by combinatorial entropy optimization. Genome Biol (2007) 3.46
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet (2011) 3.41
Transcriptional regulation by the numbers: applications. Curr Opin Genet Dev (2005) 3.40
Target mRNA abundance dilutes microRNA and siRNA activity. Mol Syst Biol (2010) 3.37
Quantitative characteristics of gene regulation by small RNA. PLoS Biol (2007) 3.35
Water mediation in protein folding and molecular recognition. Annu Rev Biophys Biomol Struct (2006) 3.32
Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. Neuron (2009) 3.27
cPath: open source software for collecting, storing, and querying biological pathways. BMC Bioinformatics (2006) 3.24
A specificity map for the PDZ domain family. PLoS Biol (2008) 3.16
Protein topology determines binding mechanism. Proc Natl Acad Sci U S A (2003) 3.16
Physical constraints and functional characteristics of transcription factor-DNA interaction. Proc Natl Acad Sci U S A (2002) 3.07
Three-dimensional structures of membrane proteins from genomic sequencing. Cell (2012) 3.02
CancerGenes: a gene selection resource for cancer genome projects. Nucleic Acids Res (2006) 3.00
Pathway information for systems biology. FEBS Lett (2005) 2.97
The developmental miRNA profiles of zebrafish as determined by small RNA cloning. Genes Dev (2005) 2.94
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature (2010) 2.85
Folding a protein in a computer: an atomic description of the folding/unfolding of protein A. Proc Natl Acad Sci U S A (2003) 2.80
Introducing meta-services for biomedical information extraction. Genome Biol (2008) 2.78
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell (2012) 2.72
Evaluation of annotation strategies using an entire genome sequence. Bioinformatics (2003) 2.66
NetPath: a public resource of curated signal transduction pathways. Genome Biol (2010) 2.62
The amino-acid mutational spectrum of human genetic disease. Genome Biol (2003) 2.55
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet (2009) 2.51
Combinatorial transcriptional control of the lactose operon of Escherichia coli. Proc Natl Acad Sci U S A (2007) 2.51
Protein structure prediction from sequence variation. Nat Biotechnol (2012) 2.50
DGCR8-dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci U S A (2008) 2.49
Conformational transitions of adenylate kinase: switching by cracking. J Mol Biol (2006) 2.49
RNA targets of wild-type and mutant FET family proteins. Nat Struct Mol Biol (2011) 2.46
Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer Res (2007) 2.44
An all-atom structure-based potential for proteins: bridging minimal models with all-atom empirical forcefields. Proteins (2009) 2.44
Models from experiments: combinatorial drug perturbations of cancer cells. Mol Syst Biol (2008) 2.33
Improved contact prediction in proteins: using pseudolikelihoods to infer Potts models. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 2.31
Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network. Clin Cancer Res (2013) 2.26
miRcode: a map of putative microRNA target sites in the long non-coding transcriptome. Bioinformatics (2012) 2.13
Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments. Proc Natl Acad Sci U S A (2013) 2.13
The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proc Natl Acad Sci U S A (2009) 2.09
A survey of flexible protein binding mechanisms and their transition states using native topology based energy landscapes. J Mol Biol (2005) 1.99
Quantifying the roughness on the free energy landscape: entropic bottlenecks and protein folding rates. J Am Chem Soc (2004) 1.99