Published in Int J Med Sci on August 01, 2015
Autophagy and Tubular Cell Death in the Kidney. Semin Nephrol (2016) 0.77
Autophagy Has a Beneficial Role in Relieving Cigarette Smoke-Induced Apoptotic Death in Human Gingival Fibroblasts. Int J Med Sci (2016) 0.75
Autophagy Induced FHL2 Upregulation Promotes IL-6 Production by Activating the NF-κB Pathway in Mouse Aortic Endothelial Cells after Exposure to PM2.5. Int J Mol Sci (2017) 0.75
Chlorogenic Acid Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/NF-κB Signal Pathway. Inflammation (2016) 0.75
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Autophagy: renovation of cells and tissues. Cell (2011) 11.59
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature (2008) 11.39
Network organization of the human autophagy system. Nature (2010) 11.38
Autophagy in immunity and inflammation. Nature (2011) 11.16
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2010) 9.02
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci U S A (1982) 8.71
p62 at the crossroads of autophagy, apoptosis, and cancer. Cell (2009) 5.97
Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem Sci (2005) 5.01
The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb Perspect Biol (2009) 4.53
A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B. EMBO J (1994) 4.04
Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney Int (2008) 3.45
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest (2010) 3.44
Rapamycin pre-treatment protects against apoptosis. Hum Mol Genet (2006) 2.57
Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. Am J Pathol (2010) 2.24
Autophagy protects the proximal tubule from degeneration and acute ischemic injury. J Am Soc Nephrol (2011) 2.04
TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis. Kidney Int (2013) 2.03
Autophagy in proximal tubules protects against acute kidney injury. Kidney Int (2012) 1.98
Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol (2002) 1.96
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.93
Autophagy is required for the activation of NFκB. Cell Cycle (2012) 1.89
Severe sepsis and septic shock: review of the literature and emergency department management guidelines. Ann Emerg Med (2006) 1.82
The cell cycle and acute kidney injury. Kidney Int (2009) 1.81
Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy. Am J Respir Crit Care Med (2010) 1.80
Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo. Clin Exp Nephrol (2009) 1.74
Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol (2008) 1.71
The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-kB (NF-kB). Curr Drug Targets (2000) 1.61
Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci (2004) 1.57
Autophagy protects renal tubular cells against cyclosporine toxicity. Autophagy (2008) 1.53
Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent. Crit Care Med (2012) 1.52
Participation of autophagy in renal ischemia/reperfusion injury. Biochem Biophys Res Commun (2008) 1.46
Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection. Sci Signal (2012) 1.45
Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy. Transplantation (2007) 1.28
Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury. Am J Pathol (2011) 1.27
Cytosolic LC3 ratio as a quantitative index of macroautophagy. Methods Enzymol (2009) 1.26
Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. PLoS One (2013) 1.21
Autophagy activation by NFkappaB is essential for cell survival after heat shock. Autophagy (2009) 1.20
Pathophysiology of cisplatin-induced acute kidney injury. Biomed Res Int (2014) 1.18
Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology (2012) 1.18
Autophagy in pulmonary macrophages mediates lung inflammatory injury via NLRP3 inflammasome activation during mechanical ventilation. Am J Physiol Lung Cell Mol Physiol (2014) 1.03
Paclitaxel ameliorates lipopolysaccharide-induced kidney injury by binding myeloid differentiation protein-2 to block Toll-like receptor 4-mediated nuclear factor-κB activation and cytokine production. J Pharmacol Exp Ther (2013) 1.02
Autophagy in acute kidney injury. Semin Nephrol (2013) 0.98
Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat. PLoS One (2012) 0.95
Role of TLR4 in lipopolysaccharide-induced acute kidney injury: protection by blueberry. Free Radic Biol Med (2014) 0.95
Age-associated molecular changes in the kidney in aged mice. Oxid Med Cell Longev (2012) 0.95
Leonurine ameliorates LPS-induced acute kidney injury via suppressing ROS-mediated NF-κB signaling pathway. Fitoterapia (2014) 0.94
Autophagosomal IkappaB alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappaB (NF-kappaB) activity. J Biol Chem (2011) 0.93
Ischemic preconditioning attenuates renal ischemia-reperfusion injury by inhibiting activation of IKKbeta and inflammatory response. Am J Nephrol (2009) 0.90
Sepsis: update in the management. Adv Chronic Kidney Dis (2013) 0.90
The cellular autophagy markers Beclin-1 and LC3B-II are increased during reperfusion in fibrillated mouse hearts. Curr Pharm Des (2013) 0.87
Acute kidney injury in patients with sepsis and septic shock: risk factors and clinical outcomes. Yonsei Med J (2013) 0.87
Alpha-1 acid glycoprotein reduces hepatic leukocyte recruitment in murine models of either early endotoxemia or early sepsis. Microcirculation (2014) 0.79