Overlapping nongenomic and genomic actions of thyroid hormone and steroids.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 26303085)

Published in Best Pract Res Clin Endocrinol Metab on April 22, 2015

Authors

Stephen R Hammes1, Paul J Davis2

Author Affiliations

1: Division of Endocrinology, Department of Medicine, University of Rochester School of Medicine, Rochester, NY, USA.
2: Department of Medicine, Albany Medical College, Albany, NY, USA; Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Rensselaer, NY, USA. Electronic address: pdavis.ordwayst@gmail.com.

Articles cited by this

A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science (2005) 9.80

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology (2004) 5.20

Paxillin and focal adhesion signalling. Nat Cell Biol (2000) 4.37

Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol Endocrinol (1999) 3.74

Molecular aspects of thyroid hormone actions. Endocr Rev (2010) 3.29

Paxillin: a focal adhesion-associated adaptor protein. Oncogene (2001) 3.03

Regulation of endothelial nitric oxide synthase: location, location, location. Annu Rev Physiol (2002) 2.79

Extranuclear steroid receptors: nature and actions. Endocr Rev (2007) 2.72

Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J Clin Invest (1999) 2.71

A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem (2007) 2.34

Integrin alphaVbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology (2005) 2.34

Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem (2002) 2.31

ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol Endocrinol (2002) 2.20

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat Med (2007) 2.18

Estrogen signaling multiple pathways to impact gene transcription. Curr Genomics (2006) 2.14

Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol. Mol Biol Cell (2004) 2.07

Estrogen modulation of endothelial nitric oxide synthase. Endocr Rev (2002) 1.97

Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest (2010) 1.90

Adenosine 3',5'-monophosphate in rat uterus: acute elevation by estrogen. Proc Natl Acad Sci U S A (1967) 1.87

Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell (2004) 1.86

Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae. Circ Res (2000) 1.86

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Mol Cell (2003) 1.83

G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol. Endocrinology (2008) 1.79

Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha. Proc Natl Acad Sci U S A (2004) 1.77

27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol (2007) 1.75

GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod (2008) 1.67

Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i). J Biol Chem (2001) 1.61

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54

Hypothyroidism in patients with renal cell carcinoma: blessing or curse? Cancer (2010) 1.50

Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer. Mol Endocrinol (2000) 1.46

Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse. J Biol Chem (2008) 1.44

L-Thyroxine vs. 3,5,3'-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Am J Physiol Cell Physiol (2009) 1.43

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth. Cell Rep (2013) 1.39

Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1. J Biol Chem (2005) 1.39

Direct interactions with G α i and G βγ mediate nongenomic signaling by estrogen receptor α . Mol Endocrinol (2007) 1.33

Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells. Endocrinology (2007) 1.32

Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circ Res (2004) 1.28

G protein beta gamma subunits inhibit nongenomic progesterone-induced signaling and maturation in Xenopus laevis oocytes. Evidence for a release of inhibition mechanism for cell cycle progression. J Biol Chem (2000) 1.26

Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. J Biol Chem (2010) 1.24

Androgens regulate ovarian follicular development by increasing follicle stimulating hormone receptor and microRNA-125b expression. Proc Natl Acad Sci U S A (2014) 1.22

Evidence that androgens are the primary steroids produced by Xenopus laevis ovaries and may signal through the classical androgen receptor to promote oocyte maturation. Proc Natl Acad Sci U S A (2001) 1.22

Minireview: Recent advances in extranuclear steroid receptor actions. Endocrinology (2011) 1.20

Integrin alphaVbeta3 contains a receptor site for resveratrol. FASEB J (2006) 1.19

Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor. Endocrinology (2004) 1.12

Membrane receptor for thyroid hormone: physiologic and pharmacologic implications. Annu Rev Pharmacol Toxicol (2011) 1.12

Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors alpha and beta. Int J Oncol (2010) 1.12

Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer. Trends Endocrinol Metab (2005) 1.11

Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation. J Clin Invest (2012) 1.09

Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is anti-apoptotic. Steroids (2006) 1.08

Steroids and oocyte maturation--a new look at an old story. Mol Endocrinol (2003) 1.07

Propylthiouracil-induced chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent high grade glioma: a phase I/II study. Anticancer Res (2003) 1.06

Thyroid hormones and cancer: clinical studies of hypothyroidism in oncology. Curr Opin Endocrinol Diabetes Obes (2010) 1.05

Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR. J Biol Chem (2000) 1.04

Resveratrol is pro-apoptotic and thyroid hormone is anti-apoptotic in glioma cells: both actions are integrin and ERK mediated. Carcinogenesis (2007) 1.02

Membrane-localized estrogen receptor α is required for normal organ development and function. Dev Cell (2014) 1.01

The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha. Cell Metab (2014) 1.01

Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes. Steroids (2006) 1.00

Regulation of Xenopus oocyte meiosis arrest by G protein betagamma subunits. Curr Biol (2001) 0.99

Estrogen regulates histone deacetylases to prevent cardiac hypertrophy. Mol Biol Cell (2013) 0.99

The in vivo role of nuclear receptor corepressors in thyroid hormone action. Biochim Biophys Acta (2012) 0.98

Estrogen stimulation of cell migration involves multiple signaling pathway interactions. Endocrinology (2010) 0.96

Crosstalk between integrin αvβ3 and estrogen receptor-α is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. PLoS One (2011) 0.96

Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac). Cell Cycle (2009) 0.96

Rapid activation of endothelial NO synthase by estrogen: evidence for a steroid receptor fast-action complex (SRFC) in caveolae. Steroids (2002) 0.95

Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor. Angiogenesis (2007) 0.95

The expression of the cytoskeletal focal adhesion protein paxillin in breast cancer correlates with HER2 overexpression and may help predict response to chemotherapy: a retrospective immunohistochemical study. Breast J (2007) 0.94

Identification of the putative MAP kinase docking site in the thyroid hormone receptor-beta1 DNA-binding domain: functional consequences of mutations at the docking site. Biochemistry (2003) 0.94

Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors. Steroids (2008) 0.93

miR-219-5p modulates cell growth of papillary thyroid carcinoma by targeting estrogen receptor α. J Clin Endocrinol Metab (2014) 0.91

Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinase. Biochemistry (2001) 0.91

Testosterone and progesterone rapidly attenuate plasma membrane Gbetagamma-mediated signaling in Xenopus laevis oocytes by signaling through classical steroid receptors. Mol Endocrinol (2006) 0.90

Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Sci Signal (2014) 0.89

Adjunctive input to the nuclear thyroid hormone receptor from the cell surface receptor for the hormone. Thyroid (2013) 0.88

Differential expression patterns and clinical significance of estrogen receptor-α and β in papillary thyroid carcinoma. BMC Cancer (2014) 0.87

Acetylation of nuclear hormone receptor superfamily members: thyroid hormone causes acetylation of its own receptor by a mitogen-activated protein kinase-dependent mechanism. Steroids (2005) 0.86

Expression of estrogen receptor, progesterone receptor, and vascular endothelial growth factor-A in thyroid cancer. Am Surg (2009) 0.86

Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop. J Biol Chem (2006) 0.85

Serum levels of sex hormones and expression of their receptors in thyroid tissue in female patients with various types of thyroid neoplasms. Pathol Res Pract (2014) 0.85

Rapid activation of endothelial nitric oxide synthase by estrogen. Steroids (1999) 0.85

Thyroid hormone-regulated actin polymerization in brain. Thyroid (1997) 0.85

Thyroid hormones and mitochondria: with a brief look at derivatives and analogues. Mol Cell Endocrinol (2013) 0.85

Cytoplasm-to-nucleus shuttling of thyroid hormone receptor-beta1 (Trbeta1) is directed from a plasma membrane integrin receptor by thyroid hormone. Endocr Res (2009) 0.84

Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells. Oncotarget (2014) 0.83

The Xenopus laevis isoform of G protein-coupled receptor 3 (GPR3) is a constitutively active cell surface receptor that participates in maintaining meiotic arrest in X. laevis oocytes. Mol Endocrinol (2008) 0.83

Non-genomic actions of thyroid hormone in brain development. Steroids (2007) 0.83

Does palmitoylation target estrogen receptors to plasma membrane caveolae? IUBMB Life (2003) 0.82

G beta gamma signaling reduces intracellular cAMP to promote meiotic progression in mouse oocytes. Steroids (2006) 0.82

Nuclear monomeric integrin αv in cancer cells is a coactivator regulated by thyroid hormone. FASEB J (2013) 0.82

Point mutations in the ERα Gαi binding domain segregate nonnuclear from nuclear receptor function. Mol Endocrinol (2012) 0.82

The pro-apoptotic action of stilbene-induced COX-2 in cancer cells: convergence with the anti-apoptotic effect of thyroid hormone. Cell Cycle (2009) 0.82

Nongenomic regulation by thyroid hormone of plasma membrane ion and small molecule pumps. Discov Med (2012) 0.81

Medically induced euthyroid hypothyroxinemia may extend survival in compassionate need cancer patients: an observational study. Oncologist (2014) 0.81

Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing. PLoS One (2014) 0.80

Nongenomic steroid-triggered oocyte maturation: of mice and frogs. Steroids (2008) 0.80

Recurrence of differentiated thyroid carcinoma during full TSH suppression: is the tumor now thyroid hormone dependent? Horm Cancer (2014) 0.78