Published in Front Neurosci on August 10, 2015
Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target. Int J Mol Sci (2016) 0.78
Global ablation of the mitochondrial calcium uniporter increases glycolysis in cortical neurons subjected to energetic stressors. J Cereb Blood Flow Metab (2016) 0.75
Molecular Bases of Brain Preconditioning. Front Neurosci (2017) 0.75
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation (1986) 19.82
Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci (1999) 10.61
A proton-gated cation channel involved in acid-sensing. Nature (1997) 6.98
Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol (2003) 6.27
Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci (2006) 4.51
Acid-sensing ion channels: advances, questions and therapeutic opportunities. Trends Neurosci (2006) 3.95
Ischemic tolerance and endogenous neuroprotection. Trends Neurosci (2003) 3.44
Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states. Lancet (2003) 3.36
Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. Science (1990) 2.95
Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy. J Cereb Blood Flow Metab (2004) 2.94
Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats. J Cereb Blood Flow Metab (2006) 2.41
The stoichiometry of the cardiac sodium-calcium exchange system. J Biol Chem (1984) 2.24
Protons act as a transmitter for muscle contraction in C. elegans. Cell (2008) 2.18
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron (2005) 2.07
Ischemic tolerance. J Cereb Blood Flow Metab (2002) 2.07
In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab (2007) 1.82
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain (2006) 1.82
Ischemic postconditioning as a novel avenue to protect against brain injury after stroke. J Cereb Blood Flow Metab (2009) 1.77
The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation. J Biol Chem (1992) 1.76
Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats. Stroke (2008) 1.65
CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.60
Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3. J Biol Chem (1996) 1.57
The Akt signaling pathway contributes to postconditioning's protection against stroke; the protection is associated with the MAPK and PKC pathways. J Neurochem (2008) 1.54
Molecular physiology of preconditioning-induced brain tolerance to ischemia. Physiol Rev (2008) 1.54
Rapid preconditioning protects rats against ischemic neuronal damage after 3 but not 7 days of reperfusion following global cerebral ischemia. J Cereb Blood Flow Metab (1997) 1.50
Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat. Stroke (2008) 1.47
Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. Clin Neurosci (1997) 1.46
Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats. J Cereb Blood Flow Metab (2006) 1.45
Dynamics of interstitial and intracellular pH in evolving brain infarct. Am J Physiol (1991) 1.43
Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives. Pharmacol Rev (2004) 1.41
The Na-K-Cl cotransporters. Am J Physiol (1994) 1.38
Multiple transport modes of the cardiac Na+/Ca2+ exchanger. Nature (2004) 1.34
Brain acidosis. Ann Emerg Med (1985) 1.29
Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3). Am J Physiol (1998) 1.28
Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. J Biol Chem (2006) 1.25
Na-K-Cl cotransporter-mediated intracellular Na+ accumulation affects Ca2+ signaling in astrocytes in an in vitro ischemic model. J Neurosci (2004) 1.25
Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy. Stroke (2004) 1.21
Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia. J Neurosci (2005) 1.21
Ischemic preconditioning ameliorates excitotoxicity by shifting glutamate/gamma-aminobutyric acid release and biosynthesis. J Neurosci Res (2005) 1.16
Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons. Am J Physiol Cell Physiol (2004) 1.16
Ischemic preconditioning preserves mitochondrial function after global cerebral ischemia in rat hippocampus. J Cereb Blood Flow Metab (2001) 1.15
Post-ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy. FEBS J (2009) 1.14
The role of Na-K-Cl co-transporter in cerebral ischemia. Neurol Res (2005) 1.14
From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia. Curr Drug Targets (2012) 1.08
Adaptation of adult brain tissue to anoxia and hypoxia in vitro. Brain Res (1986) 1.07
Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice. Am J Physiol Cell Physiol (2004) 1.06
The regulation of Na/K/2Cl cotransport and bumetanide binding in avian erythrocytes by protein phosphorylation and dephosphorylation. Effects of kinase inhibitors and okadaic acid. J Biol Chem (1990) 1.05
Mechanisms of pHi recovery after global ischemia in the perfused heart. Circ Res (1993) 1.04
Effect of acidic reperfusion on prolongation of intracellular acidosis and myocardial salvage. Cardiovasc Res (2007) 1.04
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. Cell Calcium (2007) 1.02
Synaptic acidification enhances GABAA signaling. J Neurosci (2010) 1.02
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. Stroke (2004) 1.02
Na-H exchange in myocardium: effects of hypoxia and acidification on Na and Ca. Am J Physiol (1990) 1.01
Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K-Akt signaling pathway: a novel postconditioning strategy? Neuropharmacology (2008) 1.01
Evaluation of viral infection in the myocardium of patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol (2000) 0.99
The plasma membrane calcium pump in health and disease. FEBS J (2013) 0.98
The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death. Pflugers Arch (2006) 0.98
O2-sensing mechanisms in excitable cells: role of plasma membrane K+ channels. Annu Rev Physiol (1997) 0.97
Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning. Am J Physiol Heart Circ Physiol (2007) 0.97
Delayed recovery of intracellular acidosis during reperfusion prevents calpain activation and determines protection in postconditioned myocardium. Cardiovasc Res (2008) 0.96
Free cytosolic Ca2+ measured with Ca(2+)-selective electrodes and fura 2 in rat mesenteric resistance arteries. Am J Physiol (1993) 0.96
Role of Na-K-Cl cotransport in vascular endothelial cell volume regulation. Am J Physiol (1993) 0.96
Ischemic tolerance: the mechanisms of neuroprotective strategy. Anat Rec (Hoboken) (2009) 0.95
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning. Int J Physiol Pathophysiol Pharmacol (2010) 0.94
The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning. J Cereb Blood Flow Metab (2010) 0.94
Ischemic preconditioning stimulates sodium and proton transport in isolated rat hearts. J Clin Invest (1995) 0.93
The changes in endogenous antioxidant enzyme activity after postconditioning. Cell Mol Neurobiol (2006) 0.93
Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions. J Cereb Blood Flow Metab (2006) 0.92
The two isoforms of the Na+/Ca2+ exchanger, NCX1 and NCX3, constitute novel additional targets for the prosurvival action of Akt/protein kinase B pathway. Mol Pharmacol (2007) 0.91
Dynamic regulation of acid-sensing ion channels by extracellular and intracellular modulators. Curr Med Chem (2007) 0.90
Changes in tissue pH after circulatory arrest. Am J Physiol (1961) 0.90
NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning. Stroke (2011) 0.90
Acidosis during early reperfusion prevents myocardial stunning in perfused ferret hearts. J Clin Invest (1988) 0.90
Adeno-associated virus vector-mediated bcl-2 gene transfer into post-ischemic gerbil brain in vivo: prospects for gene therapy of ischemia-induced neuronal death. Gene Ther (2000) 0.90
Na/H exchange in cultured chick heart cells: secondary stimulation of electrogenic transport during recovery from intracellular acidosis. J Mol Cell Cardiol (1986) 0.89
Chemical mediators of pain due to tissue damage and ischemia. Prog Brain Res (2000) 0.89
Na+ channel expression and neuronal function in the Na+/H+ exchanger 1 null mutant mouse. J Neurophysiol (2003) 0.89
Importance of bicarbonate transport for protection of cardiomyocytes against reoxygenation injury. Am J Physiol Heart Circ Physiol (2000) 0.89
Possible role of opioids and KATP channels in neuroprotective effect of postconditioning in mice. Biol Pharm Bull (2008) 0.89
Effects of glycogen depletion on ischemic injury in isolated rat hearts: insights into preconditioning. Am J Physiol (1995) 0.88
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia. Neurobiol Dis (2011) 0.88
Na+/H+ exchanger inhibitor, SM-20220, is protective against excitotoxicity in cultured cortical neurons. Stroke (2003) 0.87
Brain distribution of the Na+/Ca2+ exchanger-encoding genes NCX1, NCX2, and NCX3 and their related proteins in the central nervous system. Ann N Y Acad Sci (2002) 0.87
Does Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention? Transl Stroke Res (2013) 0.86
Na+/H+ exchanger activity does not contribute to protection by ischemic preconditioning in the isolated rat heart. Circulation (1997) 0.86
Reduced calcium elevation in hippocampal CA1 neurons of ischemia-tolerant gerbils. Neuroreport (1998) 0.86
Effect of acidotic blood reperfusion on reperfusion injury after coronary artery occlusion in the dog heart. J Cardiovasc Pharmacol (1998) 0.86
Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture. J Neurochem (1996) 0.86
Effect of ischemic preconditioning on mitochondrial dysfunction and mitochondrial p53 translocation after transient global cerebral ischemia in rats. Neurochem Res (2007) 0.86
NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning. Adv Exp Med Biol (2013) 0.85
Postconditioning, a series of brief interruptions of early reperfusion, prevents neurologic injury after spinal cord ischemia. Ann Surg (2006) 0.85
Late expression of Na+/H+ exchanger 1 (NHE1) and neuroprotective effects of NHE inhibitor in the gerbil hippocampal CA1 region induced by transient ischemia. Exp Neurol (2008) 0.85
pH regulating transporters in neurons from various chemosensitive brainstem regions in neonatal rats. Am J Physiol Regul Integr Comp Physiol (2009) 0.84
Calcium movement in ischemia-tolerant hippocampal CA1 neurons after transient forebrain ischemia in gerbils. J Cereb Blood Flow Metab (1996) 0.81
nNOS and p-ERK involvement in the neuroprotection exerted by remote postconditioning in rats subjected to transient middle cerebral artery occlusion. Neurobiol Dis (2013) 0.81
Differential effects of sublethal ischemia and chemical preconditioning with 3-nitropropionic acid on protein expression in gerbil hippocampus. Life Sci (2005) 0.81
Differential cyclic AMP dependence of facilitation at Aplysia sensorimotor synapses as a function of prior stimulation: augmentation versus restoration of transmitter release. J Neurosci (1993) 0.80
Neuroprotective effects of ischemic preconditioning on global brain ischemia through up-regulation of acid-sensing ion channel 2a. Int J Mol Sci (2010) 0.80
Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage. Mol Pharmacol (2012) 0.79