Published in J Neurosci on November 24, 2010
Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala. Proc Natl Acad Sci U S A (2014) 1.49
Impact of synaptic neurotransmitter concentration time course on the kinetics and pharmacological modulation of inhibitory synaptic currents. Front Cell Neurosci (2011) 0.96
Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5. Mol Biol Cell (2011) 0.92
Presynaptic pH and vesicle fusion in Drosophila larvae neurones. Synapse (2013) 0.85
Role of pH in a nitric oxide-dependent increase in cytosolic Cl- in retinal amacrine cells. J Neurophysiol (2011) 0.84
Identification of a novel protein complex containing ASIC1a and GABAA receptors and their interregulation. PLoS One (2014) 0.84
A modulatory role of ASICs on GABAergic synapses in rat hippocampal cell cultures. Mol Brain (2016) 0.83
CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis. J Neurosci (2013) 0.81
NMDA receptor-dependent afterdepolarizations are curtailed by carbonic anhydrase 14: regulation of a short-term postsynaptic potentiation. J Neurosci (2012) 0.81
Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5. Front Physiol (2014) 0.80
Cross-reactivity of acid-sensing ion channel and Na⁺-H⁺ exchanger antagonists with nicotinic acetylcholine receptors. J Physiol (2011) 0.78
The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals. J Comp Neurol (2012) 0.78
Intracellular bicarbonate regulates action potential generation via KCNQ channel modulation. J Neurosci (2014) 0.77
Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na(+)/H(+) exchanger NHE5 to the cell surface. J Biol Chem (2014) 0.77
Extracellular protons reduce quantal content and prolong synaptic currents at the Drosophila larval neuromuscular junction. J Neurogenet (2011) 0.76
pH-dependent inhibition of native GABA(A) receptors by HEPES. Br J Pharmacol (2012) 0.76
Ionic homeostasis in brain conditioning. Front Neurosci (2015) 0.76
Acute neuroinflammation provokes intracellular acidification in mouse hippocampus. J Neuroinflammation (2016) 0.75
Extracellular pH modulates GABAergic neurotransmission in rat hypothalamus. Neuroscience (2014) 0.75
The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19. Br J Pharmacol (2016) 0.75
Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive. Proc Natl Acad Sci U S A (2017) 0.75
Analysis of Ca2+ signaling motifs that regulate proton signaling through the Na+/H+ exchanger NHX-7 during a rhythmic behavior in Caenorhabditis elegans. J Biol Chem (2013) 0.75
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature (1998) 15.09
Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature (2001) 5.98
Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. J Neurosci (1998) 4.50
H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels. Curr Opin Neurobiol (1998) 3.80
Modulation of pH by neuronal activity. Trends Neurosci (1992) 3.21
Exocytosed protons feedback to suppress the Ca2+ current in mammalian cone photoreceptors. Neuron (2001) 3.03
Differences in synaptic GABA(A) receptor number underlie variation in GABA mini amplitude. Neuron (1997) 2.66
Ionic basis of GABAA receptor channel function in the nervous system. Prog Neurobiol (1994) 2.41
Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons. Nature (1990) 2.33
Alkaline and acid transients in cerebellar microenvironment. J Neurophysiol (1983) 2.21
Protons act as a transmitter for muscle contraction in C. elegans. Cell (2008) 2.18
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell (1997) 1.75
Modulation of the N-methyl-D-aspartate channel by extracellular H+. Proc Natl Acad Sci U S A (1990) 1.73
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. Am J Physiol (1999) 1.66
Synaptic cleft acidification and modulation of short-term depression by exocytosed protons in retinal bipolar cells. J Neurosci (2003) 1.63
Neuronal glutamate uptake Contributes to GABA synthesis and inhibitory synaptic strength. J Neurosci (2003) 1.57
Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists. Biophys J (2001) 1.56
Effects of the external pH on Ca channels: experimental studies and theoretical considerations using a two-site, two-ion model. Proc Natl Acad Sci U S A (1986) 1.48
Modulation of GABA(A) receptors by hydrogen ions reveals synaptic GABA transient and a crucial role of the desensitization process. J Neurosci (2003) 1.46
Role of brainstem sodium/proton exchanger 3 for breathing control during chronic acid base imbalance. Am J Respir Crit Care Med (2007) 1.44
Site and mechanism of activation of proton-induced sodium current in chick dorsal root ganglion neurones. J Physiol (1988) 1.12
Expression and localization of Na+/H+ exchangers in rat central nervous system. Neuroscience (1997) 1.11
Receptor for protons in the membrane of sensory neurons. Brain Res (1981) 1.11
Fabrication and use of high-speed, concentric h+- and Ca2+-selective microelectrodes suitable for in vitro extracellular recording. J Neurophysiol (2006) 1.10
Blockage of chloride channels by HEPES buffer. Proc R Soc Lond B Biol Sci (1987) 1.10
PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat. J Physiol (2003) 1.09
Endogenous alkaline transients boost postsynaptic NMDA receptor responses in hippocampal CA1 pyramidal neurons. J Neurosci (2007) 1.00
HEPES prevents edema in rat brain slices. Neurosci Lett (2001) 0.93
The Na(+)/H(+) exchanger is a major pH regulator in GABAergic presynaptic nerve terminals synapsing onto rat CA3 pyramidal neurons. J Neurochem (2006) 0.92
Sodium-hydrogen exchangers and sodium-bicarbonate co-transporters: ontogeny of protein expression in the rat brain. Neuroscience (2001) 0.88
Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells. J Biol Chem (2000) 0.87
Modulation by extracellular pH of the activity of GABAA receptors on rat cerebellum granule cells. Neuroscience (1994) 0.86
Local extracellular acidification caused by Ca2+-dependent exocytosis in PC12 cells. Cell Calcium (2008) 0.85
Lithium concentration in cerebrospinal fluid of affective psychotic patients treated with lithium carbonate and its clinical response. Folia Psychiatr Neurol Jpn (1973) 0.82
Alterations in GABAA receptor occupancy occur during the postnatal development of rat Purkinje cell but not granule cell synapses. Neuropharmacology (2005) 0.82
Pharmacological characterization of extracellular pH transients evoked by selective synaptic and exogenous activation of AMPA, NMDA, and GABAA receptors in the rat hippocampal slice. J Neurophysiol (1995) 0.81
NHE3 in the human brainstem: implication for the pathogenesis of the sudden infant death syndrome (SIDS)? Adv Exp Med Biol (2008) 0.80
Flurazepam effect on GABAergic currents depends on extracellular pH. Br J Pharmacol (2008) 0.79
Seizures and transient cognitive deterioration as sequelae of acute lithium intoxication. Vet Hum Toxicol (1987) 0.78
[Tissue-specific expression of Na+ -H+ exchanger isoforms at two developmental stages of human fetus]. Sheng Li Xue Bao (2003) 0.77
Lithium-methomyl induced seizures in rats: a new model of status epilepticus? Toxicol Appl Pharmacol (2006) 0.77
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem (2011) 1.43
Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling. Circ Res (2003) 1.42
Spatiotemporal characteristics of junctional and nonjunctional focal Ca2+ release in rat atrial myocytes. Circ Res (2003) 1.24
Intracellular Ca2+ oscillations, a potential pacemaking mechanism in early embryonic heart cells. J Gen Physiol (2007) 1.20
'Pressure-flow'-triggered intracellular Ca2+ transients in rat cardiac myocytes: possible mechanisms and role of mitochondria. J Physiol (2008) 1.15
Ca2+ current-gated focal and local Ca2+ release in rat atrial myocytes: evidence from rapid 2-D confocal imaging. J Physiol (2002) 1.13
Modulation of Ca2+ signalling in rat atrial myocytes: possible role of the alpha1C carboxyl terminal. J Physiol (2003) 1.00
Diversity of atrial local Ca2+ signalling: evidence from 2-D confocal imaging in Ca2+-buffered rat atrial myocytes. J Physiol (2005) 0.95
Developmental aspects of cardiac Ca(2+) signaling: interplay between RyR- and IP(3)R-gated Ca(2+) stores. Am J Physiol Heart Circ Physiol (2010) 0.95
Cardiac calcium signalling pathologies associated with defective calmodulin regulation of type 2 ryanodine receptor. J Physiol (2013) 0.93
Diversity of Ca2+ signaling in developing cardiac cells. Ann N Y Acad Sci (2006) 0.90
Ethanol withdrawal seizure susceptibility is associated with upregulation of L- and P-type Ca2+ channel currents in rat inferior colliculus neurons. Neuropharmacology (2003) 0.90
Shear fluid-induced Ca2+ release and the role of mitochondria in rat cardiac myocytes. Ann N Y Acad Sci (2008) 0.90
Regulation of cardiac Ca(2+) channel by extracellular Na(+). Cell Calcium (2011) 0.88
Ethanol withdrawal is accompanied by downregulation of calcium channel alpha 1B subunit in rat inferior colliculus neurons. Brain Res (2006) 0.87
Local extracellular acidification caused by Ca2+-dependent exocytosis in PC12 cells. Cell Calcium (2008) 0.85
Alcohol withdrawal is associated with a downregulation of large-conductance Ca²⁺-activated K⁺ channels in rat inferior colliculus neurons. Psychopharmacology (Berl) (2013) 0.84
L-type calcium channel as a cardiac oxygen sensor. Ann N Y Acad Sci (2010) 0.81
Hypoxic regulation of cardiac Ca2+ channel: possible role of haem oxygenase. J Physiol (2012) 0.81
Modulation of local Ca2+ release sites by rapid fluid puffing in rat atrial myocytes. Cell Calcium (2006) 0.81
Cardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes. J Mol Cell Cardiol (2012) 0.81
Mechanical regulation of native and the recombinant calcium channel. Cell Calcium (2013) 0.80
A new method to detect rapid oxygen changes around cells: how quickly do calcium channels sense oxygen in cardiomyocytes? J Appl Physiol (1985) (2013) 0.80
Calcium channel dysfunction in inferior colliculus neurons of the genetically epilepsy-prone rat. Neuropharmacology (2008) 0.80
Protons enhance the gating kinetics of the alpha3/beta4 neuronal nicotinic acetylcholine receptor by increasing its apparent affinity to agonists. Mol Pharmacol (2002) 0.79
Differential modulation of beta2 and beta4 subunits of human neuronal nicotinic acetylcholine receptors by acidification. Mol Pharmacol (2004) 0.77
c-Jun is required for TGF-β-mediated cellular migration via nuclear Ca²⁺ signaling. Int J Biochem Cell Biol (2011) 0.77
NCX1 phosphorylation dilemma: a little closer to resolution. Focus on "Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A". Am J Physiol Cell Physiol (2011) 0.75
beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells. Am J Physiol Heart Circ Physiol (2009) 0.75
Triadin: the new player on excitation-contraction coupling block. Circ Res (2005) 0.75
Progress in biophysics and molecular biology of the beating heart. Prog Biophys Mol Biol (2012) 0.75