Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.

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Published in Nat Med on September 07, 2015

Authors

Britta Will1, Thomas O Vogler1, Swathi Narayanagari1, Boris Bartholdy1, Tihomira I Todorova1, Mariana da Silva Ferreira1, Jiahao Chen1, Yiting Yu2, Jillian Mayer1, Laura Barreyro1, Luis Carvajal1, Daniela Ben Neriah1, Michael Roth1, Johanna van Oers1, Sonja Schaetzlein1, Christine McMahon3, Winfried Edelmann1,4,5, Amit Verma2,4,6,7, Ulrich Steidl1,2,4,7

Author Affiliations

1: Department of Cell Biology, Albert Einstein College of Medicine, Bronx, USA.
2: Department of Medicine (Oncology), Division of Hemato-Oncology, Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, USA.
3: Department of Pathology, Albert Einstein College of Medicine, Bronx, USA.
4: Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, USA.
5: Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.
6: Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, USA.
7: Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, USA.

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