Published in Protein Sci on September 08, 2015
Electrostatic Steering Accelerates C3d:CR2 Association. J Phys Chem B (2016) 0.75
Electrostatics of nanosystems: application to microtubules and the ribosome. Proc Natl Acad Sci U S A (2001) 42.14
Very fast empirical prediction and rationalization of protein pKa values. Proteins (2005) 8.61
PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Res (2007) 7.07
AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol (2004) 6.97
Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem (2007) 5.62
Cyclic nucleotide research -- still expanding after half a century. Nat Rev Mol Cell Biol (2002) 4.16
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature (2012) 2.87
Weighted-ensemble Brownian dynamics simulations for protein association reactions. Biophys J (1996) 2.87
Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr Opin Cell Biol (2000) 2.62
Conversion of phosphorylase b to phosphorylase a in muscle extracts. J Biol Chem (1955) 1.74
Regulation and organization of adenylyl cyclases and cAMP. Biochem J (2003) 1.73
Zinc binding in proteins and solution: a simple but accurate nonbonded representation. Proteins (1995) 1.72
Acetylcholinesterase: electrostatic steering increases the rate of ligand binding. Biochemistry (1993) 1.69
The relationship of epinephrine and glucagon to liver phosphorylase. I. Liver phosphorylase; preparation and properties. J Biol Chem (1956) 1.60
Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases. FEBS J (2009) 1.52
PKA: lessons learned after twenty years. Biochim Biophys Acta (2013) 1.52
Creating order from chaos: cellular regulation by kinase anchoring. Annu Rev Pharmacol Toxicol (2012) 1.44
The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations. PLoS One (2010) 1.34
Phosphodiesterases and compartmentalized cAMP signalling in the heart. Eur J Cell Biol (2006) 1.30
Solubility and diffusion coefficient of adenosine 3':5'-monophosphate. J Biol Chem (1977) 1.14
Zinc interactions and conserved motifs of the cGMP-binding cGMP-specific phosphodiesterase suggest that it is a zinc hydrolase. J Biol Chem (1994) 1.11
Browndye: A Software Package for Brownian Dynamics. Comput Phys Commun (2010) 1.08
Compartmentalisation of second messenger signalling pathways. Curr Opin Genet Dev (2014) 1.07
Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem J (2007) 1.00
Mechanisms of cyclic AMP compartmentation revealed by computational models. J Gen Physiol (2014) 1.00
Active site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling. Biophys J (2014) 0.98
Compartmentalized cAMP/PKA signalling regulates cardiac excitation-contraction coupling. J Muscle Res Cell Motil (2006) 0.94
Cyclic AMP synthesis and hydrolysis in the normal and failing heart. Pflugers Arch (2014) 0.89
A mathematical analysis of second messenger compartmentalization. Phys Biol (2008) 0.86
Electrostatic channeling in P. falciparum DHFR-TS: Brownian dynamics and Smoluchowski modeling. Biophys J (2014) 0.84
Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP). J Mol Biol (2013) 0.83
Type-specific regulation of mammalian adenylyl cyclases by G protein pathways. Adv Second Messenger Phosphoprotein Res (1998) 0.81
mAKAP-a master scaffold for cardiac remodeling. J Cardiovasc Pharmacol (2015) 0.80
Compartmentalization role of A-kinase anchoring proteins (AKAPs) in mediating protein kinase A (PKA) signaling and cardiomyocyte hypertrophy. Int J Mol Sci (2014) 0.79
Role of protein kinase A in regulating mitochondrial function and neuronal development: implications to neurodegenerative diseases. Rev Neurosci (2015) 0.79
Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg Med Chem Lett (2011) 0.78