Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.

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Published in Behav Genet on September 11, 2015

Authors

Stéphanie M van den Berg1, Marleen H M de Moor2,3,4, Karin J H Verweij5,6, Robert F Krueger7, Michelle Luciano8,9, Alejandro Arias Vasquez10,11,12,13, Lindsay K Matteson7, Jaime Derringer14, Tõnu Esko15, Najaf Amin16, Scott D Gordon5, Narelle K Hansell5, Amy B Hart17, Ilkka Seppälä18, Jennifer E Huffman19, Bettina Konte20, Jari Lahti21,22, Minyoung Lee23, Mike Miller7, Teresa Nutile24, Toshiko Tanaka25, Alexander Teumer26, Alexander Viktorin27, Juho Wedenoja28, Abdel Abdellaoui2, Goncalo R Abecasis29, Daniel E Adkins30, Arpana Agrawal31, Jüri Allik32,33, Katja Appel34, Timothy B Bigdeli23, Fabio Busonero35, Harry Campbell36, Paul T Costa37, George Davey Smith38, Gail Davies8,9, Harriet de Wit39, Jun Ding40, Barbara E Engelhardt41, Johan G Eriksson22,42,43,44,45, Iryna O Fedko2, Luigi Ferrucci25, Barbara Franke10,11,12, Ina Giegling20, Richard Grucza31, Annette M Hartmann20, Andrew C Heath31, Kati Heinonen21, Anjali K Henders5, Georg Homuth46, Jouke-Jan Hottenga2, William G Iacono7, Joost Janzing11, Markus Jokela21, Robert Karlsson27, John P Kemp38,47, Matthew G Kirkpatrick39, Antti Latvala28,42, Terho Lehtimäki18, David C Liewald8,9, Pamela A F Madden31, Chiara Magri48, Patrik K E Magnusson27, Jonathan Marten19, Andrea Maschio35, Hamdi Mbarek2, Sarah E Medland5, Evelin Mihailov15,49, Yuri Milaneschi50, Grant W Montgomery5, Matthias Nauck51, Michel G Nivard2, Klaasjan G Ouwens2, Aarno Palotie52,53, Erik Pettersson27, Ozren Polasek54, Yong Qian40, Laura Pulkki-Råback21, Olli T Raitakari55,56, Anu Realo32, Richard J Rose57, Daniela Ruggiero24, Carsten O Schmidt26, Wendy S Slutske58, Rossella Sorice24, John M Starr9,59, Beate St Pourcain38,60,61, Angelina R Sutin25,62, Nicholas J Timpson38, Holly Trochet19, Sita Vermeulen12,63, Eero Vuoksimaa28, Elisabeth Widen53, Jasper Wouda64,2, Margaret J Wright5, Lina Zgaga36,65, Generation Scotland, David Porteous66, Alessandra Minelli48, Abraham A Palmer17,39, Dan Rujescu20, Marina Ciullo24, Caroline Hayward19, Igor Rudan36, Andres Metspalu15,33, Jaakko Kaprio28,42,53, Ian J Deary8,9, Katri Räikkönen21, James F Wilson19,36, Liisa Keltikangas-Järvinen21, Laura J Bierut31, John M Hettema23, Hans J Grabe34,67, Brenda W J H Penninx50, Cornelia M van Duijn16, David M Evans38, David Schlessinger40, Nancy L Pedersen27, Antonio Terracciano22,25, Matt McGue7,68, Nicholas G Martin5, Dorret I Boomsma2

Author Affiliations

1: Department of Research Methodology, Measurement and Data-Analysis (OMD), Faculty of Behavioural, Management, and Social Sciences, University of Twente, PO Box 217, 7500 AE, Enschede, The Netherlands. stephanie.vandenberg@utwente.nl.
2: Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands.
3: Department of Clinical Child and Family Studies, VU University Amsterdam, Amsterdam, The Netherlands.
4: Department of Methods, VU University Amsterdam, Amsterdam, The Netherlands.
5: QIMR Berghofer Medical Research Institute, Brisbane, Australia.
6: Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands.
7: Department of Psychology, University of Minnesota, Minneapolis, USA.
8: Department of Psychology, University of Edinburgh, Edinburgh, UK.
9: Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
10: Donders Institute for Cognitive Neuroscience, Radboud University Nijmegen, Nijmegen, The Netherlands.
11: Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
12: Department of Human Genetics, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
13: Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
14: Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
15: Estonian Genome Center, University of Tartu, Tartu, Estonia.
16: Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
17: Department of Human Genetics, University of Chicago, Chicago, IL, USA.
18: Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland.
19: MRC Human Genetics Unit, MRC IGMM, Western General Hospital, University of Edinburgh, Edinburgh, UK.
20: Department of Psychiatry, University of Halle, Halle, Germany.
21: Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.
22: Folkhälsan Research Center, Helsinki, Finland.
23: Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
24: Institute of Genetics and Biophysics "A. Buzzati-Traverso" - CNR, Naples, Italy.
25: National Institute on Aging, NIH, Baltimore, MD, USA.
26: Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
27: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
28: Department of Public Health, University of Helsinki, Helsinki, Finland.
29: Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
30: Pharmacotherapy & Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA.
31: Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
32: Department of Psychology, University of Tartu, Tartu, Estonia.
33: Estonian Academy of Sciences, Tallinn, Estonia.
34: Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
35: Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
36: Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
37: Behavioral Medicine Research Center, Duke University School of Medicine, Durham, NC, USA.
38: Medical Research Council Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
39: Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, USA.
40: Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
41: Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
42: National Institute for Health and Welfare (THL), Helsinki, Finland.
43: Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
44: Unit of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
45: Vasa Central Hospital, Vaasa, Finland.
46: Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
47: Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia.
48: Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
49: Department of Biotechnology, University of Tartu, Tartu, Estonia.
50: Department of Psychiatry, EMGO+ Institute, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
51: Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
52: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
53: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
54: Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.
55: Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
56: Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
57: Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN, USA.
58: Department of Psychological Sciences and Missouri Alcoholism Research Center, University of Missouri, Columbia, MO, USA.
59: Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
60: School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
61: School of Experimental Psychology, University of Bristol, Bristol, UK.
62: College of Medicine, Florida State University, Tallahassee, FL, USA.
63: Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
64: Department of Research Methodology, Measurement and Data-Analysis (OMD), Faculty of Behavioural, Management, and Social Sciences, University of Twente, PO Box 217, 7500 AE, Enschede, The Netherlands.
65: Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland.
66: Medical Genetics Section, Centre for Genomics and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, The University of Edinburgh, Edinburgh, UK.
67: Department of Psychiatry and Psychotherapy, HELIOS Hospital Stralsund, Stralsund, Germany.
68: Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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