Published in Mar Drugs on September 08, 2015
Trimethylamine N-Oxide: The Good, the Bad and the Unknown. Toxins (Basel) (2016) 0.75
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study. Lipids Health Dis (2015) 0.75
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature (2011) 13.53
Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA (2002) 8.11
Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA (2006) 7.73
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ (2002) 7.14
MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA (2002) 5.29
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA (1993) 5.21
Homocysteine and cardiovascular disease. Annu Rev Med (1998) 4.69
Carnitine--metabolism and functions. Physiol Rev (1983) 3.57
The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J Biol Chem (1959) 3.05
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide. Eur Heart J (2014) 2.08
Dietary precursors of trimethylamine in man: a pilot study. Food Chem Toxicol (1999) 1.90
Carnitine metabolism and its regulation in microorganisms and mammals. Annu Rev Nutr (1998) 1.63
Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J Biol Chem (1996) 1.52
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord (2007) 1.47
Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. J Nutr (2003) 1.45
Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr (1993) 1.36
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure. J Intern Med (2014) 1.35
Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med (2012) 1.27
Trimethylamine oxide counteracts effects of hydrostatic pressure on proteins of deep-sea teleosts. J Exp Zool (2001) 1.24
Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study. PLoS One (2014) 1.23
Homocysteine lowering interventions for preventing cardiovascular events. Cochrane Database Syst Rev (2009) 1.17
Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometry. Clin Chem Lab Med (2007) 1.16
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr (2007) 1.16
Trimethylamine oxide stabilizes teleost and mammalian lactate dehydrogenases against inactivation by hydrostatic pressure and trypsinolysis. J Exp Biol (1999) 1.16
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER. J Biol Chem (1964) 1.12
Methionine metabolism in mammals: kinetic study of betaine-homocysteine methyltransferase. Arch Biochem Biophys (1972) 1.11
Chemical pathology of homocysteine. IV. Excitotoxicity, oxidative stress, endothelial dysfunction, and inflammation. Ann Clin Lab Sci (2009) 1.09
Methionine sulfoxide reductase A is a stereospecific methionine oxidase. Proc Natl Acad Sci U S A (2011) 1.07
Gut microbiota metabolism of L-carnitine and cardiovascular risk. Atherosclerosis (2013) 1.02
Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. Eur J Nutr (2012) 1.01
Omega-3 fatty acids and cardiovascular disease: new developments and applications. Postgrad Med (2013) 0.97
Docosahexaenoic acid decreases plasma homocysteine via regulating enzyme activity and mRNA expression involved in methionine metabolism. Nutrition (2010) 0.92
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. Lipids Health Dis (2013) 0.90
Dietary choline and betaine intakes and risk of cardiovascular diseases: review of epidemiological evidence. ARYA Atheroscler (2011) 0.89
High consumption of Ω-3 polyunsaturated fatty acids decrease plasma homocysteine: a meta-analysis of randomized, placebo-controlled trials. Nutrition (2011) 0.89
Homocysteine level and risk of different stroke types: a meta-analysis of prospective observational studies. Nutr Metab Cardiovasc Dis (2014) 0.88
Hyperhomocysteinemia and high-density lipoprotein metabolism in cardiovascular disease. Clin Chem Lab Med (2007) 0.88
Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metabolism (2012) 0.87
Dimethylglycine Deficiency and the Development of Diabetes. Diabetes (2015) 0.85
Are dietary choline and betaine intakes determinants of total homocysteine concentration? Am J Clin Nutr (2010) 0.85
Purification of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide with an antihypertensive effect from loach (Misgurnus anguillicaudatus). J Agric Food Chem (2012) 0.84
Mechanism of mammalian cobalamin-dependent methionine biosynthesis. Biochemistry (1971) 0.84
Dietary proteins with high isoflavone content or low methionine-glycine and lysine-arginine ratios are hypocholesterolaemic and lower the plasma homocysteine level in male Zucker fa/fa rats. Br J Nutr (2005) 0.83
Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. Mol Nutr Food Res (2013) 0.82
Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats. Nutrition (2008) 0.82
Phospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults. Lipids Health Dis (2014) 0.81
Seasonal variations of trimethylamine oxide and urea in the blood of a cold-adapted marine teleost, the rainbow smelt. Fish Physiol Biochem (1994) 0.80
Biosynthesis of trimethylamine oxide in the nurse shark, Ginglymostoma cirratum. Comp Biochem Physiol A Comp Physiol (1972) 0.79
Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis. BMC Cardiovasc Disord (2014) 0.79
A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats. Mar Drugs (2015) 0.79
Evolutionary comparison of enzyme activities of phosphatidylcholine metabolism in the nervous system of an invertebrate (Loligo pealei), lower vertebrate (Mustelus canis) and the rat. Comp Biochem Physiol B Biochem Mol Biol (1995) 0.76
Modulation of tissue fatty acids by L-carnitine attenuates metabolic syndrome in diet-induced obese rats. Food Funct (2015) 0.76
Methionine formation by transmethylation in vitro. J Biol Chem (1947) 0.76