Urine Club Cell 16-kDa Secretory Protein and Childhood Wheezing Illnesses After Lower Respiratory Tract Infections in Infancy.

Response to García-Nieto et al. Comments on Beamer et al. Association of Children's Urinary CC16 Levels with Arsenic Concentrations in Multiple Environmental Media. Int. J. Environ. Res. Public Health 2016, 13, 521. Int J Environ Res Public Health (2016) 0.75

International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J (1995) 13.01

Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA (1999) 8.07

Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med (2008) 6.35

Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med (2000) 5.24

A genome-wide search for quantitative trait loci underlying asthma. Nature (1996) 3.58

Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet (1989) 2.85

Role of viral respiratory infections in asthma and asthma exacerbations. Lancet (2010) 2.60

Community-acquired lower respiratory tract infections: etiology and treatment. Chest (2001) 2.32

Lung epithelium-specific proteins: characteristics and potential applications as markers. Am J Respir Crit Care Med (1999) 2.32

Determinants of asthma after severe respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol (2012) 2.27

Influence of maternal asthma on the cause and severity of infant acute respiratory tract infections. J Allergy Clin Immunol (2012) 2.26

Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort. Thorax (2008) 2.25

A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects. Biomarkers (2007) 2.02

The severity-dependent relationship of infant bronchiolitis on the risk and morbidity of early childhood asthma. J Allergy Clin Immunol (2009) 1.91

International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire: validation of the asthma component among Brazilian children. J Investig Allergol Clin Immunol (1999) 1.85

Dexamethasone and salbutamol in the treatment of acute wheezing in infants. Pediatrics (1983) 1.80

The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature. Pediatr Infect Dis J (2007) 1.67

Clara cell secretory protein (CC16): characteristics and perspectives as lung peripheral biomarker. Clin Exp Allergy (2000) 1.66

Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med (2015) 1.65

Direct medical costs of bronchiolitis hospitalizations in the United States. Pediatrics (2006) 1.57

Clara cell protein in serum and bronchoalveolar lavage. Eur Respir J (1992) 1.49

Cross-sectional and longitudinal association of the secretoglobin 1A1 gene A38G polymorphism with asthma phenotype in the Perth Infant Asthma Follow-up cohort. Clin Exp Allergy (2009) 1.44

Clara cell secretory protein decreases lung inflammation after acute virus infection. Am J Physiol (1998) 1.39

Club cell 10-kDa protein attenuates airway mucus hypersecretion and inflammation. Eur Respir J (2014) 1.39

Clara cell secretory protein modulates lung inflammatory and immune responses to respiratory syncytial virus infection. J Immunol (2003) 1.20

The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases. Respirology (2010) 1.18

Serum levels of CC16, SP-A and SP-B reflect tobacco-smoke exposure in asymptomatic subjects. Eur Respir J (2002) 1.18

Serum and BAL Clara cell 10 kDa protein (CC10) levels and CC10-positive bronchiolar cells are decreased in smokers. Eur Respir J (1997) 1.16

Early respiratory infections and childhood asthma. Pediatrics (2000) 1.14

Uteroglobin inhibits phospholipase A2 activity. Life Sci (1986) 1.12

Serum levels of Clara cell 10-kDa protein are decreased in patients with asthma. Lung (1999) 1.08

Potent inhibition of both human interferon-gamma production and biologic activity by the Clara cell protein CC16. Am J Respir Cell Mol Biol (1995) 1.07

Exploring the time dependence of serum clara cell protein as a biomarker of pulmonary injury in humans. Chest (2006) 1.04

Inhaled LPS induces blood release of Clara cell specific protein (CC16) in human beings. J Allergy Clin Immunol (2005) 1.01

Serum levels of Clara cell secretory protein, asthma, and lung function in the adult general population. J Allergy Clin Immunol (2013) 0.98

Association between plasma CC16 levels, the A38G polymorphism, and asthma. Am J Respir Crit Care Med (2000) 0.98

Outcome value of Clara cell protein in serum of patients with acute respiratory distress syndrome. Intensive Care Med (2006) 0.98

Infant frequent wheezing correlated to Clara cell protein 10 (CC10) polymorphism and concentration, but not allergy sensitization, in a perinatal cohort study. J Allergy Clin Immunol (2007) 0.92

Uteroglobin: structure, molecular biology, and new perspectives on its function as a phospholipase A2 inhibitor. Endocr Rev (1987) 0.90

Respiratory illnesses in early life and asthma and atopy in childhood. J Allergy Clin Immunol (2006) 0.89

Serum CC-10 in inflammatory lung diseases. Respiration (2004) 0.88

Clara cell secretory protein: determination of serum levels by an enzyme immunoassay and its importance as an indicator of bronchial asthma in children. J Pharm Biomed Anal (2004) 0.87

Clara cell 16-kd protein downregulates T(H)2 differentiation of human naive neonatal T cells. J Allergy Clin Immunol (2007) 0.87

Tumor necrosis factor-alpha stimulates human Clara cell secretory protein production by human airway epithelial cells. Am J Respir Cell Mol Biol (1998) 0.87

Methodological aspects on measurement of Clara cell protein in urine as a biomarker for airway toxicity, compared with serum levels. J Appl Toxicol (2007) 0.85

Secretoglobin 1A member 1 (SCGB1A1) +38A/G polymorphism is associated with asthma risk: a meta-analysis. Gene (2013) 0.82

The CC16 A38G polymorphism is associated with the development of asthma in children with allergic rhinitis. Clin Exp Allergy (2011) 0.81

Clara cell protein 16: A biomarker for detecting secondary respiratory complications in patients with multiple injuries. J Trauma Acute Care Surg (2012) 0.79

Repression of CC16 by cigarette smoke (CS) exposure. PLoS One (2015) 0.79

Damage-associated molecular pattern and innate cytokine release in the airways of competitive swimmers. Allergy (2015) 0.77

Association of serum Clara cell protein CC16 with respiratory infections and immune response to respiratory pathogens in elite athletes. Respir Res (2014) 0.77

Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke. J Expo Sci Environ Epidemiol (2012) 0.76