Published in Expert Rev Ophthalmol on December 01, 2010
The Human Eye Proteome Project: perspectives on an emerging proteome. Proteomics (2013) 1.23
Lipid composition of the human eye: are red blood cells a good mirror of retinal and optic nerve fatty acids? PLoS One (2012) 0.96
sCD44 overexpression increases intraocular pressure and aqueous outflow resistance. Mol Vis (2013) 0.81
Molecular biomarkers in glaucoma. Invest Ophthalmol Vis Sci (2013) 0.81
sCD44 internalization in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2013) 0.76
ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol Vis (2015) 0.76
The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol (2006) 25.47
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med (2007) 6.80
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med (2002) 5.70
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people. Arch Neurol (2010) 5.53
Primary open-angle glaucoma. N Engl J Med (2009) 4.89
TLRs and innate immunity. Blood (2008) 3.96
Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol (2006) 2.98
Heat-shock proteins as activators of the innate immune system. Trends Immunol (2002) 2.96
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. J Biol Chem (2007) 2.82
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet (2010) 2.75
Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals. Ophthalmology (1984) 2.68
Age-related changes in trabecular meshwork cellularity. Invest Ophthalmol Vis Sci (1981) 2.66
Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res (2002) 2.62
Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nat Med (2001) 2.45
CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am J Clin Pathol (2008) 2.34
Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem (2009) 2.33
Extracellular matrix in the trabecular meshwork. Exp Eye Res (2008) 2.29
Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension. Ophthalmology (2006) 2.28
Oxidative stress markers in aqueous humor of glaucoma patients. Am J Ophthalmol (2004) 2.19
Delaying treatment of ocular hypertension: the ocular hypertension treatment study. Arch Ophthalmol (2010) 2.14
The genetics of primary open-angle glaucoma: a review. Exp Eye Res (2008) 2.14
Five-year incidence of open-angle glaucoma: the visual impairment project. Ophthalmology (2002) 2.05
TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Invest Ophthalmol Vis Sci (2006) 2.02
Effects of TGF-beta2 in perfused human eyes. Invest Ophthalmol Vis Sci (2004) 2.00
Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J Immunol (2008) 1.89
Mitochondrial abnormalities in patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2006) 1.84
Changes in aqueous humor dynamics with age and glaucoma. Prog Retin Eye Res (2005) 1.82
Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation. Prostaglandins Leukot Essent Fatty Acids (2009) 1.80
Cytoskeletal involvement in the regulation of aqueous humor outflow. Invest Ophthalmol Vis Sci (2000) 1.72
Glaucomatous outflow pathway and oxidative stress. Exp Eye Res (2006) 1.71
Transforming growth factor beta 2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development. Graefes Arch Clin Exp Ophthalmol (2001) 1.62
Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2003) 1.59
Matrix metalloproteinases and tumor necrosis factor alpha in glaucomatous optic nerve head. Arch Ophthalmol (2000) 1.58
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci (2009) 1.56
Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch Ophthalmol (2004) 1.52
Changes in gene expression by trabecular meshwork cells in response to mechanical stretching. Invest Ophthalmol Vis Sci (2005) 1.52
High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease. J Neurol Sci (2006) 1.49
Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection. Proc Natl Acad Sci U S A (2010) 1.49
Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection. PLoS Pathog (2010) 1.39
Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest (2008) 1.39
Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment. Arch Neurol (2007) 1.36
Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2005) 1.34
Higher concentration of transforming growth factor-beta in aqueous humor of glaucomatous eyes and diabetic eyes. Jpn J Ophthalmol (2002) 1.32
Cellular senescence in the glaucomatous outflow pathway. Exp Gerontol (2005) 1.32
Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand. J Neurosci (2008) 1.30
Recent developments in understanding the pathophysiology of elevated intraocular pressure. Curr Opin Ophthalmol (2006) 1.29
Glycosaminoglycans of the human trabecular meshwork in primary open-angle glaucoma. Invest Ophthalmol Vis Sci (1996) 1.26
Tumor necrosis factor-alpha concentrations in the aqueous humor of patients with glaucoma. Invest Ophthalmol Vis Sci (2009) 1.25
Matrix metalloproteinases and their tissue inhibitors in aqueous humor of patients with primary open-angle glaucoma, exfoliation syndrome, and exfoliation glaucoma. J Glaucoma (2005) 1.25
Autoantibodies to small heat shock proteins in glaucoma. Invest Ophthalmol Vis Sci (1998) 1.24
Vascular endothelial growth factor is increased in aqueous humor of glaucomatous eyes. J Glaucoma (2002) 1.20
Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs (2007) 1.20
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol (2006) 1.19
Ultrasound activates the TM ELAM-1/IL-1/NF-kappaB response: a potential mechanism for intraocular pressure reduction after phacoemulsification. Invest Ophthalmol Vis Sci (2003) 1.17
A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm's canal endothelial cells. Br J Ophthalmol (2005) 1.16
Mitochondrial damage in the trabecular meshwork of patients with glaucoma. Arch Ophthalmol (2010) 1.14
Plasma and aqueous humor endothelin levels in primary open-angle glaucoma. J Glaucoma (1997) 1.12
Multiplex cytokine analysis reveals elevated concentration of interleukin-8 in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci (2010) 1.12
Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest Ophthalmol Vis Sci (2007) 1.11
Effects of modifiers of glycosaminoglycan biosynthesis on outflow facility in perfusion culture. Invest Ophthalmol Vis Sci (2008) 1.11
Monocyte modulation of aqueous outflow and recruitment to the trabecular meshwork following selective laser trabeculoplasty. Arch Ophthalmol (2010) 1.10
Effect of age on superoxide dismutase activity of human trabecular meshwork. Invest Ophthalmol Vis Sci (1996) 1.10
Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-beta1 and dexamethasone in vitro. Exp Eye Res (2004) 1.09
TLR4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases. J Clin Immunol (2009) 1.08
Ultrastructural localization of collagen IV, fibronectin, and laminin in the trabecular meshwork of normal and glaucomatous eyes. Ophthalmic Res (2001) 1.07
Multiple biomarker panels for cardiovascular risk assessment. N Engl J Med (2008) 1.06
Serum autoantibodies to alpha-fodrin are present in glaucoma patients from Germany and the United States. Invest Ophthalmol Vis Sci (2006) 1.06
Increased plasma endothelin-1 levels in patients with progressive open angle glaucoma. Br J Ophthalmol (2005) 1.04
Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor. Curr Eye Res (2007) 1.03
Primary open-angle glaucoma patients have reduced levels of blood docosahexaenoic and eicosapentaenoic acids. Prostaglandins Leukot Essent Fatty Acids (2006) 1.03
Soluble CD44 is cytotoxic to trabecular meshwork and retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2005) 1.02
Elastosis of the lamina cribrosa in glaucomatous optic neuropathy. Exp Eye Res (1998) 1.01
Heat shock proteins, immunity and glaucoma. Brain Res Bull (2004) 1.01
Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci (2010) 1.01
Localization of elastin in the normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci (1994) 1.00
Increased expression of matrix metalloproteinases in mononuclear blood cells of normal-tension glaucoma patients. J Glaucoma (2004) 1.00
Cochlin in the eye: functional implications. Prog Retin Eye Res (2007) 0.98
T cell subsets and sIL-2R/IL-2 levels in patients with glaucoma. Am J Ophthalmol (2001) 0.97
Plasminogen activator inhibitor-1 in the aqueous humor of patients with and without glaucoma. Arch Ophthalmol (2005) 0.97
Enhanced tenascin expression associated with reactive astrocytes in human optic nerve heads with primary open angle glaucoma. Exp Eye Res (1999) 0.95
Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma. Exp Eye Res (2009) 0.94
Primary trabecular meshwork cells incubated in human aqueous humor differ from cells incubated in serum supplements. Invest Ophthalmol Vis Sci (2005) 0.93
Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci (2008) 0.93
Effect of excess synthesis of extracellular matrix components by trabecular meshwork cells: possible consequence on aqueous outflow. Exp Eye Res (2007) 0.92
Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2008) 0.92
Hyaluronic acid in the normal and glaucomatous optic nerve. Exp Eye Res (1997) 0.91
Serum autoantibodies to heat shock proteins in glaucoma patients from Japan and the United States. Ophthalmology (2001) 0.88
Increased levels of Helicobacter pylori IgG antibodies in aqueous humor of patients with primary open-angle and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol (2003) 0.88
What are the biomarkers for glaucoma? Surv Ophthalmol (2007) 0.87
Detection of Alzheimer peptides and chemokines in the aqueous humor. Eur J Ophthalmol (2011) 0.87
Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure. Invest Ophthalmol Vis Sci (2008) 0.87
Analysis of autoantibodies against human retinal antigens in sera of patients with glaucoma and ocular hypertension. Curr Eye Res (2008) 0.87
Hypophosphorylation of aqueous humor sCD44 and primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2005) 0.87
Growth factors and cytokines/chemokines as surrogate biomarkers in cerebrospinal fluid and blood for diagnosing Alzheimer's disease and mild cognitive impairment. Exp Gerontol (2009) 0.86
Pharmacogenomics and clinical biomarkers in drug discovery and development. Am J Clin Pathol (2005) 0.86
Plasma thymulin and nerve growth factor levels in patients with primary open angle glaucoma and elevated intraocular pressure. Graefes Arch Clin Exp Ophthalmol (2005) 0.86
Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis (2007) 0.86
Aqueous humor sCD44 concentration and visual field loss in primary open-angle glaucoma. J Glaucoma (2007) 0.86
Plasma vascular endothelial growth factor, soluble VEGF receptor FLT-1, and von Willebrand factor in glaucoma. Br J Ophthalmol (2002) 0.86
Concentration of hyaluronic acid in primary open-angle glaucoma aqueous humor. Exp Eye Res (2005) 0.85