Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. I. Construction of a RIP1 deletion strain and isolation of temperature-sensitive mutants.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 2645276)

Published in J Biol Chem on March 05, 1989

Authors

J D Beckmann1, P O Ljungdahl, B L Trumpower

Author Affiliations

1: Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03756.

Articles citing this

Disruption of genes encoding subunits of yeast vacuolar H(+)-ATPase causes conditional lethality. Proc Natl Acad Sci U S A (1990) 2.14

Cytochrome bc1 complexes of microorganisms. Microbiol Rev (1990) 1.73

The nature and mechanism of superoxide production by the electron transport chain: Its relevance to aging. J Am Aging Assoc (2000) 1.22

Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis. J Biol Chem (2006) 1.10

Paracoccus denitrificans cytochrome c1 gene replacement mutants. J Bacteriol (1990) 1.05

MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol (1994) 0.89

The Rieske Iron-Sulfur Protein: Import and Assembly into the Cytochrome bc(1) Complex of Yeast Mitochondria. Bioinorg Chem Appl (2011) 0.82

The Rieske FeS protein encoded and synthesized within mitochondria complements a deficiency in the nuclear gene. Proc Natl Acad Sci U S A (2003) 0.80

Transient expression of βC1 protein differentially regulates host genes related to stress response, chloroplast and mitochondrial functions. Virol J (2010) 0.78

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein. Proc Natl Acad Sci U S A (2015) 0.77

Functional analysis in yeast of cDNA coding for the mitochondrial Rieske iron-sulfur protein of higher plants. Proc Natl Acad Sci U S A (1991) 0.76

Assembly of deletion mutants of the Rieske iron-sulfur protein into the cytochrome bc1 complex of yeast mitochondria. J Bioenerg Biomembr (1997) 0.75

Articles by these authors

A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res (1990) 11.96

Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell (1992) 10.94

Simultaneous determination of hemes a, b, and c from pyridine hemochrome spectra. Anal Biochem (1987) 5.10

Specific roles of protein-phospholipid interactions in the yeast cytochrome bc1 complex structure. EMBO J (2001) 2.24

Isolation of ubiquinol oxidase from Paracoccus denitrificans and resolution into cytochrome bc1 and cytochrome c-aa3 complexes. J Biol Chem (1985) 2.11

Sensors of extracellular nutrients in Saccharomyces cerevisiae. Curr Genet (2001) 2.09

Qsr1p, a 60S ribosomal subunit protein, is required for joining of 40S and 60S subunits. Mol Cell Biol (1997) 1.92

kem mutations affect nuclear fusion in Saccharomyces cerevisiae. Genetics (1990) 1.87

Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids. Mol Cell Biol (1999) 1.83

QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex, codes for a 60 S ribosomal subunit protein. J Biol Chem (1997) 1.77

Differential effects of antimycin on ubisemiquinone bound in different environments in isolated succinate . cytochrome c reductase complex. J Biol Chem (1980) 1.67

Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. J Cell Biol (1996) 1.65

Purification of a reconstitutively active iron-sulfur protein (oxidation factor) from succinate . cytochrome c reductase complex of bovine heart mitochondria. J Biol Chem (1979) 1.61

Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol (2001) 1.49

Purification of highly active cytochrome bc1 complexes from phylogenetically diverse species by a single chromatographic procedure. Biochim Biophys Acta (1987) 1.44

The presence of redox-sensitive nickel in the periplasmic hydrogenase from Desulfovibrio gigas. Biochem Biophys Res Commun (1982) 1.44

Alteration of the midpoint potential and catalytic activity of the rieske iron-sulfur protein by changes of amino acids forming hydrogen bonds to the iron-sulfur cluster. J Biol Chem (1998) 1.30

SQT1, which encodes an essential WD domain protein of Saccharomyces cerevisiae, suppresses dominant-negative mutations of the ribosomal protein gene QSR1. Mol Cell Biol (1997) 1.28

Isolation and characterization of the nuclear gene encoding the Rieske iron-sulfur protein (RIP1) from Saccharomyces cerevisiae. J Biol Chem (1987) 1.24

Evidence for nickel and a three-iron center in the hydrogenase of Desulfovibrio desulfuricans. J Biol Chem (1982) 1.22

Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae. Genetics (2001) 1.17

Shr3p mediates specific COPII coatomer-cargo interactions required for the packaging of amino acid permeases into ER-derived transport vesicles. Mol Biol Cell (1999) 1.16

QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex, is homologous to a gene implicated in eukaryotic cell differentiation. J Biol Chem (1995) 1.12

New concepts on the role of ubiquinone in the mitochondrial respiratory chain. J Bioenerg Biomembr (1981) 1.10

The interaction between mitochondrial NADH-ubiquinone oxidoreductase and ubiquinol-cytochrome c oxidoreductase. Restoration of ubiquinone-pool behaviour. Biochem J (1978) 1.10

The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol (2001) 1.10

An inhibitor of mitochondrial respiration which binds to cytochrome b and displaces quinone from the iron-sulfur protein of the cytochrome bc1 complex. J Biol Chem (1984) 1.08

Function of the iron-sulfur protein of the cytochrome b-c1 segment in electron-transfer and energy-conserving reactions of the mitochondrial respiratory chain. Biochim Biophys Acta (1981) 1.08

A method for determining the in vivo topology of yeast polytopic membrane proteins demonstrates that Gap1p fully integrates into the membrane independently of Shr3p. J Biol Chem (2000) 1.07

Purification of a three-subunit ubiquinol-cytochrome c oxidoreductase complex from Paracoccus denitrificans. J Biol Chem (1986) 1.04

Evidence for a concerted mechanism of ubiquinol oxidation by the cytochrome bc1 complex. J Biol Chem (2000) 1.03

Isolation and characterization of COX12, the nuclear gene for a previously unrecognized subunit of Saccharomyces cerevisiae cytochrome c oxidase. J Biol Chem (1992) 1.02

Diminished inhibition of mitochondrial electron transfer from succinate to cytochrome c by thenoyltrifluoroacetone induced by antimycin. J Biol Chem (1979) 1.02

Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. III. Import, protease processing, and assembly into the cytochrome bc1 complex of iron-sulfur protein lacking the iron-sulfur cluster. J Biol Chem (1991) 1.00

Mechanism of ubiquinol oxidation by the cytochrome bc1 complex: pre-steady-state kinetics of cytochrome bc1 complexes containing site-directed mutants of the Rieske iron-sulfur protein. Biochim Biophys Acta (1998) 0.99

Technique for simultaneous determination of [s]sulfide and [C]carbon dioxide in anaerobic aqueous samples. Appl Environ Microbiol (1981) 0.98

Subunit 8 of the Saccharomyces cerevisiae cytochrome bc1 complex interacts with succinate-ubiquinone reductase complex. J Bioenerg Biomembr (1996) 0.98

Studies on ubiquinone. Demonstration of the total biosynthesis of ubiquinone-9 in rat liver mitochondria. J Biol Chem (1974) 0.97

The mitochondrial targeting presequence of the Rieske iron-sulfur protein is processed in a single step after insertion into the cytochrome bc1 complex in mammals and retained as a subunit in the complex. J Biol Chem (1993) 0.96

Exchangeability of Qsr1p, a large ribosomal subunit protein required for subunit joining, suggests a novel translational regulatory mechanism. FEBS Lett (1997) 0.95

Extreme evolutionary conservation of QM, a novel c-Jun associated transcription factor. Hum Mol Genet (1994) 0.93

An analogue of ubiquinone which inhibits respiration by binding to the iron-sulfur protein of the cytochrome b-c1 segment of the mitochondrial respiratory chain. J Biol Chem (1982) 0.93

Mutational analysis of assembly and function of the iron-sulfur protein of the cytochrome bc1 complex in Saccharomyces cerevisiae. J Bioenerg Biomembr (1993) 0.92

Two-step processing is not essential for the import and assembly of functionally active iron-sulfur protein into the cytochrome bc1 complex in Saccharomyces cerevisiae. J Biol Chem (1997) 0.92

Intermediate length Rieske iron-sulfur protein is present and functionally active in the cytochrome bc1 complex of Saccharomyces cerevisiae. J Biol Chem (1999) 0.91

Studies on ubiquinone. The isolation and identification of 5-demethoxyubiquinone-9 as an intermediate in biosynthesis of ubiquinone-9 in the rat. J Biol Chem (1972) 0.91

Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex. J Biol Chem (1994) 0.91

Changes to the length of the flexible linker region of the Rieske protein impair the interaction of ubiquinol with the cytochrome bc1 complex. Eur J Biochem (2000) 0.91

Subunit 6 regulates half-of-the-sites reactivity of the dimeric cytochrome bc1 complex in Saccharomyces cerevisiae. J Biol Chem (1990) 0.90

The petite phenotype resulting from a truncated copy of subunit 6 results from loss of assembly of the cytochrome bc1 complex and can be suppressed by overexpression of subunit 9. J Biol Chem (1991) 0.89

Isolation and characterization of QCR9, a nuclear gene encoding the 7.3-kDa subunit 9 of the Saccharomyces cerevisiae ubiquinol-cytochrome c oxidoreductase complex. An intron-containing gene with a conserved sequence occurring in the intron of COX4. J Biol Chem (1990) 0.89

Ubiquinone at center N is responsible for triphasic reduction of cytochrome b in the cytochrome bc(1) complex. J Biol Chem (1999) 0.89

Protonmotive Q cycle pathway of electron transfer and energy transduction in the three-subunit ubiquinol-cytochrome c oxidoreductase complex of Paracoccus denitrificans. J Biol Chem (1988) 0.88

Deletion of QCR6, the gene encoding subunit six of the mitochondrial cytochrome bc1 complex, blocks maturation of cytochrome c1, and causes temperature-sensitive petite growth in Saccharomyces cerevisiae. J Biol Chem (1994) 0.87

Heterologous complementation reveals that mutant alleles of QSR1 render 60S ribosomal subunits unstable and translationally inactive. Nucleic Acids Res (1998) 0.86

Subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex is required for insertion of EPR-detectable iron-sulfur cluster into the Rieske iron-sulfur protein. J Biol Chem (1993) 0.86

Protease maturation of the Rieske iron-sulphur protein after its insertion into the mitochondrial cytochrome bc1 complex of Saccharomyces cerevisiae. Biochem Soc Trans (1994) 0.85

Acidic regions of cytochrome c1 are essential for ubiquinol-cytochrome c reductase activity in yeast cells lacking the acidic QCR6 protein. J Biochem (1993) 0.85

Purification and properties of succinate-ubiquinone oxidoreductase complex from Paracoccus denitrificans. Biochim Biophys Acta (1988) 0.85

Deletion of subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex specifically impairs electron transfer at the ubiquinol oxidase site (center P) in the bc1 complex. FEBS Lett (1992) 0.84

Inhibition of electron transfer in the cytochrome b-c, segment of the mitochondrial respiratory chain by a synthetic analogue of ubiquinone. J Bioenerg Biomembr (1980) 0.84

The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones. J Cell Sci (2000) 0.84

Evidence for a protonmotive Q cycle mechanism of electron transfer through the cytochrome b-c1 complex. Biochem Biophys Res Commun (1976) 0.84

Mucidin and strobilurin A are identical and inhibit electron transfer in the cytochrome bc1 complex of the mitochondrial respiratory chain at the same site as myxothiazol. Biochemistry (1986) 0.84

Strain-dependent variation in carbon source regulation of nucleus-encoded mitochondrial proteins of Saccharomyces cerevisiae. J Bacteriol (1995) 0.83

Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. II. Biochemical characterization of temperature-sensitive RIP1- mutations. J Biol Chem (1989) 0.83

Role of the Rieske iron-sulfur protein midpoint potential in the protonmotive Q-cycle mechanism of the cytochrome bc1 complex. J Bioenerg Biomembr (1999) 0.83

Mössbauer and EPR studies on nitrite reductase from Thiobacillus denitrificans. J Biol Chem (1982) 0.82

Processing of the presequence of the Schizosaccharomyces pombe Rieske iron-sulfur protein occurs in a single step and can be converted to two-step processing by mutation of a single proline to serine in the presequence. J Biol Chem (1998) 0.82

Reconstitution of the iron-sulfur protein responsible for the g = 1.90 electron paramagnetic resonance signal and associated cytochrome c reductase activities to depleted succinate-cytochrome c reductase complex. J Biol Chem (1980) 0.82

Long-inverse PCR to generate regional peptide libraries by codon mutagenesis. Biotechniques (1997) 0.81

Controlled digestion with trypsin as a structural probe for the N-terminal peptide of soluble and membranous cytochrome c. Biochemistry (1975) 0.81

Effect of bathophenanthroline and carbonylcyanide-m-chlorophenyl hydrazone on cytochrome c reductase activity of resolved succinate cytochrome c reductase complex. Biochem Biophys Res Commun (1975) 0.81

Purification of cytochrome bc1 complexes from phylogenically diverse species by a single method. Methods Enzymol (1986) 0.80

Inhibition of the oxidant--induced reduction of cytochrome b by a synthetic analogue of ubiquinone. FEBS Lett (1980) 0.80

Regulation of nuclear genes encoding mitochondrial proteins in Saccharomyces cerevisiae. J Bacteriol (1995) 0.80

Triphasic reduction of cytochrome b and the protonmotive Q cycle pathway of electron transfer in the cytochrome bc1 complex of the mitochondrial respiratory chain. J Biol Chem (1986) 0.80

Dissociation of import of the Rieske iron-sulfur protein into Saccharomyces cerevisiae mitochondria from proteolytic processing of the presequence. J Biol Chem (1996) 0.79

The AUG start codon of the Saccharomyces cerevisiae NFS1 gene can be substituted for by UUG without increased initiation of translation at downstream codons. Eur J Biochem (2001) 0.79

Rapid reduction of cytochrome c1 in the presence of antimycin and its implication for the mechanism of electron transfer in the cytochrome b-c1 segment of the mitochondrial respiratory chain. J Biol Chem (1981) 0.78

Controlled reduction of cytochrome b in succinate-cytochrome c reductase complex by succinate in the presence of ascorbate and antimycin. Biochem Biophys Res Commun (1975) 0.78

Aromatic amino acids in the Rieske iron-sulfur protein do not form an obligatory conduit for electron transfer from the iron-sulfur cluster to the heme of cytochrome c1 in the cytochrome bc1 complex. Biochim Biophys Acta (1999) 0.78

Resolution and reconstitution of the iron-sulfur protein of the cytochrome bc1 segment of the mitochondrial respiratory chain. Methods Enzymol (1986) 0.77

Isolation of a three-subunit cytochrome bc1 complex from Paracoccus denitrificans. Methods Enzymol (1986) 0.77

Identification of oxidation factor as a reconstitutively active form of the iron-sulfur protein of the cytochrome b-c1 segment of the respiratory chain. FEBS Lett (1979) 0.77

Identification of a stable ubisemiquinone and characterization of the effects of ubiquinone oxidation-reduction status on the Rieske iron-sulfur protein in the three-subunit ubiquinol-cytochrome c oxidoreductase complex of Paracoccus denitrificans. J Biol Chem (1987) 0.77

The cleaved presequence is not required for import of subunit 6 of the cytochrome bc1 complex into yeast mitochondria or assembly into the complex. FEBS Lett (1999) 0.77

Function of the iron-sulfur protein of the cytochrome b-c1 segment in electron transfer reactions of the mitochondrial respiratory chain. J Biol Chem (1982) 0.76

Involvement of the iron-sulfur protein of the mitochondrial cytochrome b-c1 complex in the oxidant-induced reduction of cytochrome b. FEBS Lett (1981) 0.76

A simple, one-step purification of cytochrome b from the bc1 complexes of bacteria. FEBS Lett (1987) 0.76

QCR9, the nuclear gene encoding a small subunit of the mitochondrial cytochrome bc1 complex, maps to the right arm of chromosome VII in Saccharomyces cerevisiae. Yeast (1993) 0.76

Heterologous complementation of a Rieske iron-sulfur protein-deficient Saccharomyces cerevisiae by the Rip1 gene of Schizosaccharomyces pombe. J Biol Chem (1996) 0.75

The N terminus of the Qcr7 protein of the cytochrome bc1 complex is not essential for import into mitochondria in Saccharomyces cerevisiae but is essential for assembly of the complex. J Biol Chem (1997) 0.75

Restoration of pool function type behavior to succinate dehydrogenase having latent reconstitutive activity in ubiquinol-cytochrome c reductase complex. Biochem Biophys Res Commun (1978) 0.75

The biosynthesis of isoprenoid lipids including ubiquinone in muscle from normal and genetically dystrophic mice. Arch Biochem Biophys (1970) 0.75

Diminished inhibition of succinate-cytochrome c reductase activity of resolved reductase complex by thenoyltrifluoroacetone in the presence of antimycin. Biochem Biophys Res Commun (1978) 0.75