Computational evidence that fast translation speed can increase the probability of cotranslational protein folding.

Does mRNA structure contain genetic information for regulating co-translational protein folding? Zool Res (2017) 0.75

Fast Protein Translation Can Promote Co- and Posttranslational Folding of Misfolding-Prone Proteins. Biophys J (2017) 0.75

VMD: visual molecular dynamics. J Mol Graph (1996) 117.02

Molecular dynamics simulations of unfolding and refolding of a beta-hairpin fragment of protein G. Proc Natl Acad Sci U S A (1999) 3.61

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins. Nat Struct Mol Biol (2009) 3.21

Experimental tests of villin subdomain folding simulations. J Mol Biol (2003) 3.08

Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations. Proc Natl Acad Sci U S A (2007) 1.99

Common structural transitions in explicit-solvent simulations of villin headpiece folding. Biophys J (2009) 1.96

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding. Nat Struct Mol Biol (2012) 1.87

All-atom fast protein folding simulations: the villin headpiece. Proteins (2002) 1.77

The efficiency of folding of some proteins is increased by controlled rates of translation in vivo. A hypothesis. J Mol Biol (1987) 1.72

alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel. Nat Struct Mol Biol (2010) 1.68

Two-stage folding of HP-35 from ab initio simulations. J Mol Biol (2007) 1.59

Folding of CFTR is predominantly cotranslational. Mol Cell (2005) 1.56

Cotranslational folding of globin. J Biol Chem (1997) 1.37

Cotranslational folding promotes beta-helix formation and avoids aggregation in vivo. J Mol Biol (2008) 1.21

Protein folding during cotranslational translocation in the endoplasmic reticulum. Mol Cell (2002) 1.19

Prediction of variable translation rate effects on cotranslational protein folding. Nat Commun (2012) 1.18

Protein folding at the exit tunnel. Annu Rev Biophys (2011) 1.17

Statics of the ribosomal exit tunnel: implications for cotranslational peptide folding, elongation regulation, and antibiotics binding. J Mol Biol (2009) 1.13

Cotranslational folding increases GFP folding yield. Biophys J (2010) 1.09

Cotranslational folding--omnia mea mecum porto? Int J Biochem Cell Biol (2001) 1.00

Cotranslational protein folding--fact or fiction? Bioinformatics (2007) 0.94

Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold. J Mol Biol (2006) 0.93

Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates. Nat Commun (2014) 0.93

Monitoring cotranslational protein folding in mammalian cells at codon resolution. Proc Natl Acad Sci U S A (2012) 0.92

Understanding the influence of codon translation rates on cotranslational protein folding. Acc Chem Res (2014) 0.92

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome. Proc Natl Acad Sci U S A (2012) 0.89

Cotranslational protein folding within the ribosome tunnel influences trigger-factor recruitment. Biophys J (2012) 0.85

Cotranslational folding of nascent proteins on Escherichia coli ribosomes. Biochem Cell Biol (1996) 0.84

A model study of protein nascent chain and cotranslational folding using hydrophobic-polar residues. Proteins (2008) 0.82

Measuring cotranslational folding of nascent polypeptide chains on ribosomes. Methods Enzymol (2009) 0.81

Cotranslational protein folding reveals the selective use of synonymous codons along the coding sequence of a low expression gene. J Genet (2014) 0.81

Structural and energetic determinants of co-translational folding. J Chem Phys (2013) 0.80

Cotranslational folding of proteins. Biochemistry (Mosc) (2000) 0.80

Lattice simulations of cotranslational folding of single domain proteins. Proteins (2008) 0.80

Cotranslational folding of proteins. Biochem Cell Biol (1996) 0.80

Role of cotranslational disulfide bond formation in the folding of the hemagglutinin-neuraminidase protein of Newcastle disease virus. Virology (1996) 0.79

Cotranslational protein folding and terminus hydrophobicity. Adv Bioinformatics (2011) 0.78

Simulation study of the role of the ribosomal exit tunnel on protein folding. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 0.76