Published in Trends Biochem Sci on October 21, 2015
Cilium assembly and disassembly. Nat Cell Biol (2016) 0.80
Permeability barriers for generating a unique ciliary protein and lipid composition. Curr Opin Cell Biol (2016) 0.80
Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements. Nat Struct Mol Biol (2017) 0.79
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol Biol Cell (2017) 0.79
Role for the IFT-A Complex in Selective Transport to the Primary Cilium. Cell Rep (2016) 0.79
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome. Sci Rep (2016) 0.78
The role of the dynein light intermediate chain in retrograde IFT and flagellar function in Chlamydomonas. Mol Biol Cell (2016) 0.77
Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice. Mol Biol Cell (2016) 0.77
Microtubule Motors Drive Hedgehog Signaling in Primary Cilia. Trends Cell Biol (2016) 0.76
Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery. FEBS J (2017) 0.76
Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis. PLoS Genet (2017) 0.75
Fixation methods can differentially affect ciliary protein immunolabeling. Cilia (2017) 0.75
Deep Sequencing of the Human Retinae Reveals the Expression of Odorant Receptors. Front Cell Neurosci (2017) 0.75
TGFβ1 - induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner. Sci Rep (2016) 0.75
The development and functions of multiciliated epithelia. Nat Rev Mol Cell Biol (2017) 0.75
The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein-TbBILBO1. Cells (2016) 0.75
Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. PLoS Genet (2016) 0.75
The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep (2016) 0.75
Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46. J Biol Chem (2017) 0.75
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome. J Cell Biol (2017) 0.75
Protein arginine methyltransferases interact with intraflagellar transport particles and change location during flagellar growth and resorption. Mol Biol Cell (2017) 0.75
Protein transport in growing and steady-state cilia. Traffic (2017) 0.75
IFT54 regulates IFT20 stability but is not essential for tubulin transport during ciliogenesis. Cell Mol Life Sci (2017) 0.75
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations. Cell Rep (2017) 0.75
Compound heterozygous alterations in intraflagellar transport protein CLUAP1 in a child with a novel Joubert and oral-facial-digital overlap syndrome. Cold Spring Harb Mol Case Stud (2017) 0.75
Intraflagellar transport. Nat Rev Mol Cell Biol (2002) 10.86
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell (2007) 10.75
The primary cilium: a signalling centre during vertebrate development. Nat Rev Genet (2010) 8.81
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell (1998) 8.16
Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J Cell Biol (1998) 7.22
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol (2000) 7.04
Proteomic analysis of a eukaryotic cilium. J Cell Biol (2005) 6.54
A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci U S A (1993) 6.50
The renewal of photoreceptor cell outer segments. J Cell Biol (1967) 5.81
The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J Cell Biol (1995) 4.78
Flagellar regeneration in protozoan flagellates. J Cell Biol (1967) 4.57
The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol Biol Cell (2006) 4.18
PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts. Curr Biol (2005) 4.04
The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J Cell Biol (1999) 3.97
A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J Cell Biol (1998) 3.90
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell (2010) 3.83
Intraflagellar transport particles participate directly in cilium-generated signaling in Chlamydomonas. Cell (2006) 3.79
Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol (2007) 3.76
Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr Biol (2001) 3.58
Functional coordination of intraflagellar transport motors. Nature (2005) 3.43
A proteomic analysis of human cilia: identification of novel components. Mol Cell Proteomics (2002) 3.23
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev (2004) 3.21
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia. Proc Natl Acad Sci U S A (2008) 3.21
Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas. Mol Biol Cell (1999) 3.20
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis. J Cell Biol (2011) 3.11
CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. J Cell Biol (2010) 3.07
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med (2009) 2.99
A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia. Nat Cell Biol (2012) 2.81
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell (2008) 2.73
Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans. J Cell Biol (1999) 2.67
Polarity of flagellar assembly in Chlamydomonas. J Cell Biol (1992) 2.66
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J Cell Biol (2009) 2.55
Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases. J Cell Biol (2001) 2.52
Role of primary cilia in the pathogenesis of polycystic kidney disease. J Am Soc Nephrol (2007) 2.44
Intraflagellar transport is required for the vectorial movement of TRPV channels in the ciliary membrane. Curr Biol (2005) 2.42
Light-driven translocation of signaling proteins in vertebrate photoreceptors. Trends Cell Biol (2006) 2.36
Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function. Hum Mol Genet (2006) 2.32
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (2013) 2.25
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J Cell Biol (2008) 2.20
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol (2007) 2.16
Identification of an outer segment targeting signal in the COOH terminus of rhodopsin using transgenic Xenopus laevis. J Cell Biol (2000) 2.14
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Dev Cell (2014) 2.09
The site of in vivo assembly of flagellar microtubules. Ann N Y Acad Sci (1975) 2.01
An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. Genes Dev (2011) 2.00
The role of preassembled cytoplasmic complexes in assembly of flagellar dynein subunits. Mol Biol Cell (1998) 1.98
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev (2010) 1.95
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella. J Cell Biol (2007) 1.94
Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia. Genes Dev (2011) 1.94
A differential cargo-loading model of ciliary length regulation by IFT. Curr Biol (2013) 1.92
Targeting proteins to the ciliary membrane. Curr Top Dev Biol (2008) 1.92
The cilium secretes bioactive ectosomes. Curr Biol (2013) 1.88
Dissecting the molecular mechanisms of intraflagellar transport in chlamydomonas. Curr Biol (2006) 1.63
The kinases LF4 and CNK2 control ciliary length by feedback regulation of assembly and disassembly rates. Curr Biol (2013) 1.63
Electron-tomographic analysis of intraflagellar transport particle trains in situ. J Cell Biol (2009) 1.56
Ciliary disorder of the skeleton. Am J Med Genet C Semin Med Genet (2012) 1.55
Architecture and function of IFT complex proteins in ciliogenesis. Differentiation (2011) 1.55
The bld1 mutation identifies the Chlamydomonas osm-6 homolog as a gene required for flagellar assembly. Curr Biol (2001) 1.54
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking. J Cell Biol (2012) 1.54
ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery. J Cell Biol (2008) 1.53
The BBSome controls IFT assembly and turnaround in cilia. Nat Cell Biol (2012) 1.50
Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments. Nat Cell Biol (2011) 1.47
Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins. Cell Mol Life Sci (2010) 1.45
The FLA3 KAP subunit is required for localization of kinesin-2 to the site of flagellar assembly and processive anterograde intraflagellar transport. Mol Biol Cell (2004) 1.42
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Dev Cell (2014) 1.40
Kinesin-II is preferentially targeted to assembling cilia and is required for ciliogenesis and normal cytokinesis in Tetrahymena. Mol Biol Cell (1999) 1.37
Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature (2015) 1.33
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol (2013) 1.31
Crystal structure of the intraflagellar transport complex 25/27. EMBO J (2011) 1.23
Intraflagellar transport complex structure and cargo interactions. Cilia (2013) 1.20
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors. Elife (2013) 1.20
Establishing a connection between cilia and Bardet-Biedl Syndrome. Trends Mol Med (2004) 1.16
Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase. J Cell Biol (2013) 1.16
Evolution of modular intraflagellar transport from a coatomer-like progenitor. Proc Natl Acad Sci U S A (2013) 1.11
The blind leading the obese: the molecular pathophysiology of a human obesity syndrome. Trans Am Clin Climatol Assoc (2010) 1.09
Intraflagellar transport proteins cycle between the flagellum and its base. J Cell Sci (2012) 1.09
22S axonemal dynein is preassembled and functional prior to being transported to and attached on the axonemes. Cell Motil Cytoskeleton (1994) 1.08
Intraflagellar transport drives flagellar surface motility. Elife (2013) 1.07
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system. J Cell Sci (2014) 1.05
Sequential assembly of flagellar radial spokes. Cytoskeleton (Hoboken) (2011) 1.04
The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function. J Cell Biol (2012) 1.03
Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism. J Cell Biol (2015) 0.98
Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia. Nat Commun (2014) 0.98
Compartmentalized calcium signaling in cilia regulates intraflagellar transport. Curr Biol (2013) 0.97
Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly. J Cell Biol (2014) 0.96
FLA8/KIF3B phosphorylation regulates kinesin-II interaction with IFT-B to control IFT entry and turnaround. Dev Cell (2014) 0.96
Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT. Curr Biol (2013) 0.95
The retrograde IFT machinery of C. elegans cilia: two IFT dynein complexes? PLoS One (2011) 0.94
NPHP proteins: gatekeepers of the ciliary compartment. J Cell Biol (2010) 0.93
Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding. Elife (2015) 0.92
Uncoordinated (UNC)119: coordinating the trafficking of myristoylated proteins. Vision Res (2012) 0.91
The global phosphoproteome of Chlamydomonas reinhardtii reveals complex organellar phosphorylation in the flagella and thylakoid membrane. Mol Cell Proteomics (2014) 0.88
Bitter and sweet taste receptors in the respiratory epithelium in health and disease. J Mol Med (Berl) (2014) 0.87
A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids. Curr Biol (2014) 0.87
Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells. PLoS One (2014) 0.85
Somatic CRISPR-Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia. J Cell Biol (2015) 0.85
Assembly of IFT trains at the ciliary base depends on IFT74. Curr Biol (2015) 0.85
Structural basis for membrane targeting of the BBSome by ARL6. Nat Struct Mol Biol (2014) 0.83
Getting tubulin to the tip of the cilium: one IFT train, many different tubulin cargo-binding sites? Bioessays (2014) 0.83
Paramecium BBS genes are key to presence of channels in Cilia. Cilia (2012) 0.83
The ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking. Cytoskeleton (Hoboken) (2014) 0.81