Published in Cell on May 05, 2006
Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol (2010) 2.67
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J Cell Biol (2009) 2.55
Intraflagellar transport and cilium-based signaling. Cell (2006) 2.35
Sensory signaling-dependent remodeling of olfactory cilia architecture in C. elegans. Dev Cell (2008) 2.26
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol (2007) 2.16
Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium. J Cell Biol (2009) 2.10
Primary cilia and signaling pathways in mammalian development, health and disease. Nephron Physiol (2009) 2.09
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev (2010) 1.95
The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes. Genes Dev (2008) 1.95
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella. J Cell Biol (2007) 1.94
Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors. Dev Dyn (2008) 1.73
Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. PLoS Biol (2008) 1.63
Functional redundancy of the B9 proteins and nephrocystins in Caenorhabditis elegans ciliogenesis. Mol Biol Cell (2008) 1.59
Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access. J Cell Biol (2012) 1.55
ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery. J Cell Biol (2008) 1.53
Retrograde intraflagellar transport mutants identify complex A proteins with multiple genetic interactions in Chlamydomonas reinhardtii. Genetics (2009) 1.52
Intraflagellar transport molecules in ciliary and nonciliary cells of the retina. J Cell Biol (2010) 1.50
Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments. Nat Cell Biol (2011) 1.47
Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans. EMBO J (2007) 1.45
The roles of evolutionarily conserved functional modules in cilia-related trafficking. Nat Cell Biol (2013) 1.42
IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport. Dev Cell (2012) 1.40
The ciliary membrane. Curr Opin Cell Biol (2010) 1.36
The primary cilium as a Hedgehog signal transduction machine. Methods Cell Biol (2009) 1.35
Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease. PLoS One (2012) 1.32
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol (2013) 1.31
Intraflagellar transport (IFT) protein IFT25 is a phosphoprotein component of IFT complex B and physically interacts with IFT27 in Chlamydomonas. PLoS One (2009) 1.30
Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoS One (2007) 1.28
The ubiquitin conjugation system is involved in the disassembly of cilia and flagella. J Cell Biol (2009) 1.23
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors. Elife (2013) 1.20
How do cilia organize signalling cascades? Philos Trans R Soc Lond B Biol Sci (2014) 1.19
A CDK-related kinase regulates the length and assembly of flagella in Chlamydomonas. J Cell Biol (2007) 1.13
Motility and more: the flagellum of Trypanosoma brucei. Nat Rev Microbiol (2014) 1.11
Different effects of Tetrahymena IFT172 domains on anterograde and retrograde intraflagellar transport. Mol Biol Cell (2008) 1.09
Intraflagellar transport drives flagellar surface motility. Elife (2013) 1.07
Ciliary diffusion barrier: the gatekeeper for the primary cilium compartment. Cytoskeleton (Hoboken) (2011) 1.04
Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol Biol Cell (2011) 1.03
TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein. Hum Mol Genet (2010) 1.01
IFT-Cargo Interactions and Protein Transport in Cilia. Trends Biochem Sci (2015) 0.98
Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT. Curr Biol (2013) 0.95
Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding. Elife (2015) 0.92
The primary cilia, a 'Rab-id' transit system for hedgehog signaling. Curr Opin Cell Biol (2007) 0.91
Evolutionarily conserved Delta(25(27))-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii. J Lipid Res (2012) 0.89
Whole genome sequencing identifies a deletion in protein phosphatase 2A that affects its stability and localization in Chlamydomonas reinhardtii. PLoS Genet (2013) 0.89
Genome analysis of the unicellular green alga Chlamydomonas reinhardtii Indicates an ancient evolutionary origin for key pattern recognition and cell-signaling protein families. Genetics (2008) 0.88
Uniparental inheritance of cpDNA and the genetic control of sexual differentiation in Chlamydomonas reinhardtii. J Plant Res (2010) 0.86
Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols. Proc Natl Acad Sci U S A (2016) 0.85
Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models. J Am Soc Nephrol (2014) 0.85
The future of ciliary and flagellar membrane research. Mol Biol Cell (2012) 0.84
Gsp1 triggers the sexual developmental program including inheritance of chloroplast DNA and mitochondrial DNA in Chlamydomonas reinhardtii. Plant Cell (2012) 0.83
Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna. Mol Biol Cell (2011) 0.83
Flagellar elongation and gene expression in Chlamydomonas reinhardtii. Eukaryot Cell (2007) 0.82
Flagellar membrane trafficking in kinetoplastids. Parasitol Res (2006) 0.82
Uncovering the genetic basis for early isogamete differentiation: a case study of Ectocarpus siliculosus. BMC Genomics (2013) 0.81
Regulation of flagellar biogenesis by a calcium dependent protein kinase in Chlamydomonas reinhardtii. PLoS One (2013) 0.81
Genetic and phenotypic analysis of flagellar assembly mutants in Chlamydomonas reinhardtii. Methods Cell Biol (2009) 0.80
Synchronization, slippage, and unbundling of driven helical flagella. PLoS One (2013) 0.78
The eukaryotic flagellum makes the day: novel and unforeseen roles uncovered after post-genomics and proteomics data. Curr Protein Pept Sci (2012) 0.78
The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies. PLoS One (2015) 0.75
Trafficking to the primary cilium membrane. Mol Biol Cell (2017) 0.75
Protein transport in growing and steady-state cilia. Traffic (2017) 0.75
The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science (2007) 11.15
Cilium-generated signaling and cilia-related disorders. Lab Invest (2005) 2.42
The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes. Genes Dev (2008) 1.95
Cilia and flagella revealed: from flagellar assembly in Chlamydomonas to human obesity disorders. Cell (2004) 1.76
An aurora kinase is essential for flagellar disassembly in Chlamydomonas. Dev Cell (2004) 1.75
Chlamydomonas shortens its flagella by activating axonemal disassembly, stimulating IFT particle trafficking, and blocking anterograde cargo loading. Dev Cell (2005) 1.63
The ciliary membrane. Curr Opin Cell Biol (2010) 1.36
Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm. Mol Reprod Dev (2009) 1.33
A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas. Proc Natl Acad Sci U S A (2009) 1.30
The phosphorylation state of an aurora-like kinase marks the length of growing flagella in Chlamydomonas. Curr Biol (2011) 1.25
SnapShot: Intraflagellar transport. Cell (2009) 1.22
Kinesin-II is required for flagellar sensory transduction during fertilization in Chlamydomonas. Mol Biol Cell (2002) 1.13
The Chlamydomonas Fus1 protein is present on the mating type plus fusion organelle and required for a critical membrane adhesion event during fusion with minus gametes. Mol Biol Cell (2003) 1.11
Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates. Genes Dev (2013) 1.04
Membrane fusion triggers rapid degradation of two gamete-specific, fusion-essential proteins in a membrane block to polygamy in Chlamydomonas. Development (2010) 1.03
Kinesin II and regulated intraflagellar transport of Chlamydomonas aurora protein kinase. J Cell Sci (2003) 0.96
Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas. J Biol Chem (2003) 0.95
Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT. Curr Biol (2013) 0.95
Flagellar regeneration requires cytoplasmic microtubule depolymerization and kinesin-13. J Cell Sci (2013) 0.93
Chlamydomonas (Chlorophyceae) colony PCR. Protoplasma (2009) 0.93
Regulation of cilia assembly, disassembly, and length by protein phosphorylation. Methods Cell Biol (2009) 0.91
Evolutionarily conserved Delta(25(27))-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii. J Lipid Res (2012) 0.89
Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length. Proc Natl Acad Sci U S A (2013) 0.88
Cilia disassembly with two distinct phases of regulation. Cell Rep (2015) 0.85
An algal nucleus-encoded subunit of mitochondrial ATP synthase rescues a defect in the analogous human mitochondrial-encoded subunit. Mol Biol Cell (2002) 0.84
Protein transport and signal transduction during fertilization in chlamydomonas. Traffic (2003) 0.83
Regulation of flagellar biogenesis by a calcium dependent protein kinase in Chlamydomonas reinhardtii. PLoS One (2013) 0.81
The conserved ciliary protein Bug22 controls planar beating of Chlamydomonas flagella. J Cell Sci (2013) 0.79
A ciliary timer for S-phase entry. Nat Rev Mol Cell Biol (2007) 0.78
Controlling gas/liquid exchange using microfluidics for real-time monitoring of flagellar length in living Chlamydomonas at the single-cell level. Lab Chip (2012) 0.78
Comparative proteomics reveals timely transport into cilia of regulators or effectors as a mechanism underlying ciliary disassembly. J Proteome Res (2017) 0.75