Published in J Biomed Mater Res A on October 28, 2015
Study to Prevent Cartilage Damage Following Acute Knee Injury. | NCT00332254
Biomaterials Strategies for Generating Therapeutic Immune Responses. Adv Drug Deliv Rev (2017) 0.75
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum (2008) 19.80
Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets. Arthritis Rheum (2001) 5.24
Lifetime risk of symptomatic knee osteoarthritis. Arthritis Rheum (2008) 4.50
The impact of osteoarthritis: implications for research. Clin Orthop Relat Res (2004) 3.63
The economic burden associated with osteoarthritis, rheumatoid arthritis, and hypertension: a comparative study. Ann Rheum Dis (2004) 1.92
Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study. J Rheumatol (2005) 1.55
Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene. Gene Ther (2002) 1.53
Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles. Bioconjug Chem (2010) 1.52
In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression. Am J Pathol (1999) 1.52
One in four people may develop symptomatic hip osteoarthritis in his or her lifetime. Osteoarthritis Cartilage (2010) 1.49
Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254). Osteoarthritis Cartilage (2012) 1.30
How to achieve sustained and complete protein release from PLGA-based microparticles? Int J Pharm (2007) 1.20
Tumour necrosis factor-alpha, interleukin-1beta and interleukin-8 induce persistent mechanical nociceptor hypersensitivity. Pain (2002) 1.15
Effect of blending calcium compounds on hydrolytic degradation of poly(DL-lactic acid-co-glycolic acid). Biomaterials (2002) 1.05
Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators. Rheum Dis Clin North Am (2002) 1.03
Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins. Biomaterials (2012) 1.00
Controlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres. Int J Nanomedicine (2012) 0.98
Effectiveness of the soluble form of the interleukin-1 receptor accessory protein as an inhibitor of interleukin-1 in collagen-induced arthritis. Arthritis Rheum (2003) 0.98
Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases. J Control Release (2007) 0.93
Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. Eur Cell Mater (2015) 0.92
Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy. Arthritis Res Ther (2011) 0.92
Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells. Mol Biosyst (2011) 0.89
Sustained delivery of IL-1Ra from pluronic F127-based thermosensitive gel prolongs its therapeutic potentials. Pharm Res (2012) 0.86
The effect of anakinra, an IL1 receptor antagonist, in patients with sporadic inclusion body myositis (sIBM): a small pilot study. J Neurol Sci (2013) 0.86
Suppression of experimental osteoarthritis by adenovirus-mediated double gene transfer. Chin Med J (Engl) (2006) 0.85
IL-1Ra and its delivery strategies: inserting the association in perspective. Pharm Res (2013) 0.81
Assessment of release kinetics, stability and polymer interaction of poloxamer 407-based thermosensitive gel of interleukin-1 receptor antagonist. Pharm Dev Technol (2013) 0.80
Efficacy of daily compared to intermittent administration of IL-1Ra for protection against bone and cartilage destruction in collagen-challenged mice. Clin Exp Rheumatol (2003) 0.80
Nanoengineered particles for enhanced intra-articular retention and delivery of proteins. Adv Healthc Mater (2014) 0.80
Investigation on PEGylation strategy of recombinant human interleukin-1 receptor antagonist. Bioorg Med Chem (2007) 0.80