| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
|
Proc Natl Acad Sci U S A
|
1977
|
2.45
|
|
2
|
Primary structure of neocarzinostatin, an antitumor protein.
|
Science
|
1972
|
1.55
|
|
3
|
Solid-phase peptide synthesis using mild base cleavage of N alpha-fluorenylmethyloxycarbonylamino acids, exemplified by a synthesis of dihydrosomatostatin.
|
Int J Pept Protein Res
|
1978
|
1.43
|
|
4
|
Facile synthesis of amino acid and peptide esters under mild conditions via cesium salts.
|
J Org Chem
|
1977
|
1.38
|
|
5
|
Solid phase synthesis without repetitive acidolysis. Preparation of leucyl-alanyl-glycyl-valine using 9-fluorenylmethyloxycarbonylamino acids.
|
Int J Pept Protein Res
|
1979
|
1.31
|
|
6
|
Preparation and properties of Nalpha-9-fluorenylmethyloxycarbonylamino acids bearing tert.-butyl side chain protection.
|
Int J Pept Protein Res
|
1980
|
1.20
|
|
7
|
Conformation of lysine vasopressin: a comparison with oxytocin.
|
Proc Natl Acad Sci U S A
|
1972
|
1.08
|
|
8
|
The synthesis of biologically active pteroyloligo- 0L-glutamates (folic acid conjugates). Evaluation of ( 3 H)pteroylheptaglutamate for metabolic studies.
|
J Biol Chem
|
1972
|
1.02
|
|
9
|
A solid-phase synthesis of (8-arginine)-vasopressin through a crystalline protected nonapeptide intermediate and biological properties of the hormone.
|
J Am Chem Soc
|
1970
|
1.00
|
|
10
|
Structure-activity relationships in the actinomycins.
|
Adv Appl Microbiol
|
1973
|
0.99
|
|
11
|
A facile method of purification of neocarzinostatin, an antitumor protein.
|
J Natl Cancer Inst
|
1977
|
0.92
|
|
12
|
A solid-phase synthesis of [lysine]-vasopressin through a crystalline protected nonapeptide intermediate.
|
J Am Chem Soc
|
1968
|
0.91
|
|
13
|
Solid-phase peptide synthesis of somatostatin using mild base cleavage of N alpha-9-fluorenylmethyloxycarbonylamino acids.
|
Int J Pept Protein Res
|
1980
|
0.89
|
|
14
|
Isophosphamide as a new acrolein-producing antineoplastic isomer of cyclophosphamide.
|
Cancer Res
|
1972
|
0.87
|
|
15
|
Purification and molecular characterization of human fibroblast interferon.
|
Arch Biochem Biophys
|
1981
|
0.87
|
|
16
|
Efficient preparation of N alpha-formylamino acid tert-butyl esters.
|
J Org Chem
|
1977
|
0.84
|
|
17
|
Synthesis of somatostatin and [D-Trp8]-somatostatin.
|
Int J Pept Protein Res
|
1980
|
0.84
|
|
18
|
Synthesis of analogs and oligomers of N-(2-aminoethyl)glycine and their gastrointestinal absorption in the rat.
|
Int J Pept Protein Res
|
1984
|
0.83
|
|
19
|
Synthesis of hepta-gamma-L-glutamic acid by conventional and solid-phase techniques.
|
J Org Chem
|
1970
|
0.81
|
|
20
|
Stable isolated symmetrical anhydrides of N alpha-9-fluorenylmethyloxycarbonylamino acids in solid-phase peptide synthesis. Methionine-enkephalin synthesis as an example.
|
Int J Pept Protein Res
|
1981
|
0.81
|
|
21
|
Removal of the N alpha-benzyloxycarbonyl group from cysteine-containing peptides by catalytic hydrogenolysis in liquid ammonia, exemplified by a synthesis of oxytocin.
|
J Am Chem Soc
|
1974
|
0.81
|
|
22
|
A revised primary structure for neocarzinostatin based on fast atom bombardment and gas chromatographic-mass spectrometry.
|
J Biol Chem
|
1984
|
0.80
|
|
23
|
Structure of the antitumor protein neocarzinostatin. Amino acid sequence.
|
Arch Biochem Biophys
|
1974
|
0.78
|
|
24
|
Reduction of disulfide bonds in peptides and proteins by dithiothreitol in liquid ammonia.
|
J Am Chem Soc
|
1971
|
0.78
|
|
25
|
Peptide synthesis using the four-component condensation (Ugi reaction).
|
J Am Chem Soc
|
1977
|
0.77
|
|
26
|
Synthesis, biological activity, and tritiation of L-3, 4-dehydroproline-containing peptides.
|
Int J Pept Protein Res
|
1977
|
0.77
|
|
27
|
Pharmacological effects of introducing a double bond into a binding site of oxytocin. Analogues with L-3,4-dehydroproline in position 7.
|
J Med Chem
|
1977
|
0.77
|
|
28
|
Replacement of the disulfide bond in oxytocin by an amide group. Synthesis and some biological properties of (cyclo-(1-L-aspartic acid,6-L-alpha,beta-diaminopropionic acid))oxytocin.
|
J Med Chem
|
1978
|
0.76
|
|
29
|
Syntheses of actinomycin and analogs. 3. A total synthesis of actinomycin D (Cl) via peptide cyclization between proline and sarcosine.
|
J Am Chem Soc
|
1970
|
0.76
|
|
30
|
Influence of the complex formation between trypsin and bovine basic trypsin inhibitor on the reactivity of certain disulfide bonds.
|
Biochemistry
|
1971
|
0.76
|
|
31
|
Inhibition of phosphorylcholine binding to antibodies using synthetic peptides.
|
Nature
|
1987
|
0.76
|
|
32
|
Formation of the cytotoxic aldehyde acrolein during in vitro degradation of cyclophosphamide.
|
Nat New Biol
|
1971
|
0.76
|
|
33
|
Solid-phase synthesis with attachment of peptide to resin through an amino acid side chain: (8-lysine)-vasopressin.
|
Proc Natl Acad Sci U S A
|
1971
|
0.75
|
|
34
|
Synthesis of an actinomycin analog with substituted lactone oxygens (1',1'-bis(L-,-diaminopropionic acid))-actinomycin C (C 1).
|
Int J Protein Res
|
1971
|
0.75
|
|
35
|
Confirmation of the primary structure of thymosin alpha1 by microsequence analysis of limited acid and enzymatic hydrolysis fragments.
|
Int J Pept Protein Res
|
1983
|
0.75
|
|
36
|
The in vivo gastrointestinal absorption in rats of the intact cyclo(L-leucylglycine) dipeptide.
|
Can J Physiol Pharmacol
|
1984
|
0.75
|
|
37
|
Preparative oxidative conversion of protected peptide C alpha-hydrazides into the corresponding acids by N-bromosuccinimide.
|
Int J Pept Protein Res
|
1981
|
0.75
|
|
38
|
[Synthesis of a nonapeptide derivative with the N-terminal sequence A 1-9 of the A-chain of sheep insulin].
|
Z Naturforsch B
|
1965
|
0.75
|
|
39
|
Roderich Walter, 1937-1979.
|
Int J Pept Protein Res
|
1980
|
0.75
|
|
40
|
The gastrointestinal absorption, tissue distribution, urinary excretion and metabolism of N-(2-aminoethyl)-glycine (AEG) in the rat.
|
Life Sci
|
1980
|
0.75
|
|
41
|
On the tryptophan content of neocarzinostatin.
|
Int J Protein Res
|
1970
|
0.75
|
|
42
|
Selective tryptophan oxidation in the antitumor protein neocarzinostatin and effects on conformation and biological activity.
|
Biochemistry
|
1974
|
0.75
|
|
43
|
Synthesis of adrenal peptide E and some of its biological activities.
|
Arch Biochem Biophys
|
1983
|
0.75
|
|
44
|
Synthesis of a potent enkephalin analog, Tyr-D-Thr-Gly-Phe-delta 3 Pro-NH2, and some of its biological activities.
|
Int J Pept Protein Res
|
1986
|
0.75
|
|
45
|
Peptide E: opiate receptor binding profile in the rat brain membrane assay. Comparison with beta-endorphin.
|
Biochem Biophys Res Commun
|
1983
|
0.75
|
|
46
|
Preparative high-performance liquid chromatography applied to peptide synthesis.
|
J Chromatogr
|
1976
|
0.75
|
|
47
|
A total synthesis of actinomycin D (C1) via peptide cyclization between proline and sarcosine.
|
Experientia
|
1968
|
0.75
|
|
48
|
Synthesis of the four isomers of , -diaminobutyric acid.
|
J Antibiot (Tokyo)
|
1972
|
0.75
|
|
49
|
[A synthesis of the B-chain of insulin].
|
Z Naturforsch B
|
1965
|
0.75
|
|
50
|
Synthesis of the four stereoisomeric forms of alpha, beta-diaminobutyric acid and some derivatives suitable for peptide synthesis.
|
Hoppe Seylers Z Physiol Chem
|
1973
|
0.75
|
|
51
|
Synthesis and antitumor activity of 2-deamino- and N2-(gamma-hydroxypropyl)actinomycin D.
|
J Med Chem
|
1975
|
0.75
|
|
52
|
Synthesis of peptide analogs of actinomycin D (NSC-3053).
|
Cancer Chemother Rep
|
1974
|
0.75
|
|
53
|
Facile assignment of disulfide bonds in proteins through detection of cystine-containing peptides in peptide maps.
|
Biochem Biophys Res Commun
|
1970
|
0.75
|
|
54
|
Fluorometric-colorimetric amino acid analysis of actinomycins using fluorescamine. Mechanism of partial threonine decomposition during acid hydrolysis.
|
Anal Biochem
|
1976
|
0.75
|
|
55
|
Catalytic hydrogenolysis in liquid ammonia. Cleavage of Nalpha-benzyloxycarbonyl groups from cysteine-containing peptides with tert-butyl side chain protection. Application to a stepwise synthesis of somatostatin.
|
Int J Pept Protein Res
|
1978
|
0.75
|
|
56
|
Synthesis and some properties and antitumor effects of the actinomycin lactam analog, (di(1-L-alpha, beta-diaminopropionic))actinomycin D1.
|
J Med Chem
|
1976
|
0.75
|
|
57
|
Syntheses of actinomycin and analogs. 8. A synthesis of actinomycin D lactam.
|
J Am Chem Soc
|
1972
|
0.75
|
|
58
|
Partial sequence of the tyrosine region of neocarzinostatin.
|
Experientia
|
1972
|
0.75
|
|
59
|
Selman A. Waksman Conference on actinomycins: their potential for cancer chemotherapy. Preface.
|
Cancer Chemother Rep
|
1974
|
0.75
|
|
60
|
Facile assignment of disulfide bonds in ovine lactogenic hormone and human growth hormone.
|
Int J Pept Protein Res
|
1974
|
0.75
|
|
61
|
Computer program for localization of disulfide bonds in proteins.
|
Int J Pept Protein Res
|
1974
|
0.75
|
|
62
|
Preparation of protected peptide hydrazides from the acids and hydrazine by dicyclohexylcarbodiimide-hydroxybenzotriazole coupling.
|
Int J Pept Protein Res
|
1978
|
0.75
|
|
63
|
[Synthesis of a decapeptide derivative with the 21-30 sequence from the B-chain of human insulin].
|
Justus Liebigs Ann Chem
|
1966
|
0.75
|
|
64
|
Synthesis of peptide derivatives with actinomycin D sequence.
|
J Org Chem
|
1967
|
0.75
|
|
65
|
Synthesis of actinomycin D lactam, [1',1'-bis(L-threo- , -diaminobutyric acid)]actinomycin D.
|
J Med Chem
|
1973
|
0.75
|
|
66
|
Synthesis of human beta-endorphin in solution using benzyl-type side chain protective groups.
|
Int J Pept Protein Res
|
1980
|
0.75
|
|
67
|
[Combining of synthetic insulin chains into biologically active preparations].
|
Z Naturforsch B
|
1965
|
0.75
|
|
68
|
Preparation of 14,38-bis-[S-carbamidomethyl]-(basic trypsin inhibitor) possessing full biological activity.
|
Biochem Biophys Res Commun
|
1968
|
0.75
|
|
69
|
Reactions in liquid ammonia. 3. Complete aminoethylation of thiol groups in peptides and proteins by ethylenimmine in liquid ammonia.
|
J Biol Chem
|
1972
|
0.75
|