Published in Proc Natl Acad Sci U S A on February 01, 1977
The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytes. J Exp Med (1979) 3.15
Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Proc Natl Acad Sci U S A (1981) 1.90
Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus. Proc Natl Acad Sci U S A (1984) 1.51
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The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins. J Exp Med (1991) 1.41
Distribution of prothymosin alpha in rat tissues. Proc Natl Acad Sci U S A (1984) 1.20
Thymosin alpha 11: a peptide related to thymosin alpha 1 isolated from calf thymosin fraction 5. Proc Natl Acad Sci U S A (1983) 1.14
Increase of mouse resistance to Candida albicans infection by thymosin alpha 1. Infect Immun (1982) 1.13
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Molecular cloning of cDNA for human prothymosin alpha. Proc Natl Acad Sci U S A (1986) 1.05
Induction in vivo and in vitro of terminal deoxynucleotidyl transferase by thymosin in bone marrow cells from athymic mice. J Exp Med (1978) 0.97
Prothymosin alpha in human blood. Proc Natl Acad Sci U S A (1987) 0.96
Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ. Proc Natl Acad Sci U S A (1991) 0.94
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Translation of mRNA from calf thymus in the wheat germ system: evidence for a precursor of thymosin alpha1. Proc Natl Acad Sci U S A (1978) 0.92
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Parathymosin alpha: a peptide from rat tissues with structural homology to prothymosin alpha. Proc Natl Acad Sci U S A (1985) 0.90
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Immunolocalization of thymosin alpha 1, thymopoietin and thymulin in mouse thymic epithelial cells at different stages of culture: a light and electron microscopic study. Immunology (1988) 0.87
Induction of differentiation in human marrow T cell precursors by the synthetic serum thymic factor, FTS. Clin Exp Immunol (1980) 0.87
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Synthesis and apparent secretion of prothymosin alpha by different subpopulations of calf and rat thymocytes. Immunology (1989) 0.86
A pilot study of the safety and efficacy of thymosin alpha 1 in augmenting immune reconstitution in HIV-infected patients with low CD4 counts taking highly active antiretroviral therapy. Clin Exp Immunol (2003) 0.83
Generation of a monoclonal antibody against facteur thymique serique (FTS). Clin Exp Immunol (1982) 0.83
Purification of thymus mRNA coding for a 16,000-dalton polypeptide containing the thymosin alpha 1 sequence. Proc Natl Acad Sci U S A (1981) 0.82
Changes in surface antigens of immature thymocytes under the influence of T-cell growth factor and thymic factors. Proc Natl Acad Sci U S A (1983) 0.82
Neonatal thymus grafts. I. Studies on the regulation of the level of circulating thymic factor (FTS). Immunology (1979) 0.79
Enrichment of in vitro and in vivo immunologic activity of purified fractions of calf thymic hormone. J Exp Med (1978) 0.79
Expression and hydroxylamine cleavage of thymosin alpha 1 concatemer. J Biomed Biotechnol (2008) 0.79
Multiple sclerosis: II. Effects of prothymosin alpha on the autologous and allogeneic MLR in patients with multiple sclerosis. Clin Exp Immunol (1987) 0.78
Therapeutic approaches using host defence peptides to tackle herpes virus infections. Viruses (2009) 0.78
Effect of synthetic thymic humoral factor (THF-gamma 2) on T cell activities in immunodeficient ageing mice. Clin Exp Immunol (1992) 0.78
Expression, purification and characterization of a novel soluble human thymosin alpha1 concatemer exhibited a stronger stimulation on mice lymphocytes proliferation and higher anti-tumor activity. Int J Biol Sci (2011) 0.77
Evaluation of the morphological and functional characteristics of murine thymic non-lymphoid cells grown in vitro. J Anat (1981) 0.77
Construction, expression, and characterization of thymosin alpha 1 tandem repeats in Escherichia coli. Biomed Res Int (2013) 0.77
Induction of a T-cell specific antigen on bone marrow lymphocytes with thymus RNA. Immunology (1978) 0.76
A tumor-penetrating peptide modification enhances the antitumor activity of thymosin alpha 1. PLoS One (2013) 0.76
Syntheses of two deacetyl-thymosin alpha(1) analogues and their effects on low E-rosette-forming lymphocytes of uraemic patients. Mediators Inflamm (1996) 0.75
Amplification of the proliferative response to alloantigen by a factor present in an extract of syngeneic thymic lymphoid cells. Proc Natl Acad Sci U S A (1978) 0.75
The Gordon Wilson lecture. The history of the development of thymosin: chemistry, biology and clinical applications. Trans Am Clin Climatol Assoc (1977) 0.75
Electrophoretic mobilities of peptides on paper and their use in the determination of amide groups. Nature (1966) 12.65
Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins. Biochemistry (1974) 12.07
The estimation of polypeptide chain molecular weights by gel filtration in 6 M guanidine hydrochloride. J Biol Chem (1969) 4.77
Isoelectric focusing in polyacrylamide gel and its application to immunoglobulins. Nature (1968) 3.73
Purification and biological activity of thymosin, a hormone of the thymus gland. Proc Natl Acad Sci U S A (1972) 3.24
A new acid hydrolysis method for determining tryptophan in peptides and proteins. Anal Biochem (1974) 3.23
Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A (1966) 3.16
Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13
The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells. Biochemistry (1975) 2.51
Purification and properties of bovine thymosin. Ann N Y Acad Sci (1975) 2.08
Acetylation of Protein N-terminal amino groups structural observations on alpha-amino acetylated proteins. J Theor Biol (1975) 1.93
Thymosin activity in patients with cellular immunodeficiency. N Engl J Med (1975) 1.67
Acceleration by thymosin of the development of resistance to murine sarcoma virus-induced tumor in mice. Proc Natl Acad Sci U S A (1970) 1.38
Reaction of peptides with fluorescamine on paper after chromatography or electrophoresis. Anal Biochem (1975) 1.35
Thymosin restores T cell function and reduces the incidence of amyloid disease in casein-treated mice. J Immunol (1976) 1.31
Use of fluorescamine in the chromatographic analysis of peptides from proteins. Anal Biochem (1974) 1.26
Thymosin corrects the abnormal DNA synthetic response of NZB mouse thymocytes. Proc Natl Acad Sci U S A (1974) 1.19
The amino acid sequence of thymopoietin II. Cell (1975) 1.16
Demonstration of serum protein differences in cystic fibrosis by isoelectric focusing in thin-layer polyacrylamide gels. Clin Chim Acta (1973) 1.08
Use of thymosin in the treatment of primary immunodeficiency diseases and cancer. Med Clin North Am (1976) 1.02
In vitro and in vivo studies with thymosin in cancer patients. Ann N Y Acad Sci (1976) 1.00
Immunotherapy of the Dunning leukaemia with thymic extracts. Br J Cancer (1973) 0.96
Editorial: Thymic cells and humoral factors as therapeutic agents. Pediatrics (1976) 0.94
Reversal by thymosin of increased susceptibility of immunosuppressed mice to Moloney sarcoma virus. Transplant Proc (1971) 0.89
The RNA component of human telomerase. Science (1995) 9.86
Environmental and economic costs of soil erosion and conservation benefits. Science (1995) 8.98
Direct allelic variation scanning of the yeast genome. Science (1998) 5.90
Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA. Genes Dev (1992) 5.84
Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Ann Oncol (2005) 5.27
Genetics, physiology, and evolutionary relationships of the genus Buchnera: intracellular symbionts of aphids. Annu Rev Microbiol (1995) 4.70
Primary structure of two COOH-terminal hexapeptides from rabbit muscle aldolase: a difference in the structure of the alpha and beta subunits. Biochem Biophys Res Commun (1970) 4.68
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Ruptured aneurysms of the sinus of Valsalva in Oriental patients. J Thorac Cardiovasc Surg (1990) 4.28
T-cell co-stimulation through B7RP-1 and ICOS. Nature (1999) 4.20
Crystal structure of dimeric HIV-1 capsid protein. Nat Struct Biol (1996) 3.93
Ordering genes in a flagella pathway by analysis of expression kinetics from living bacteria. Science (2001) 3.69
Constant-infusion recombinant interleukin-2 in adoptive immunotherapy of advanced cancer. N Engl J Med (1987) 3.48
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A (2000) 3.37
Precipitation of radioactively labeled samples: a semi-automatic multiple-sample processor. Cell Immunol (1972) 3.35
Purification and biological activity of thymosin, a hormone of the thymus gland. Proc Natl Acad Sci U S A (1972) 3.24
Human platelet-derived growth factor. Purification and resolution into two active protein fractions. J Biol Chem (1981) 3.21
Results of treatment of 385 patients with peritoneal surface spread of appendiceal malignancy. Ann Surg Oncol (1999) 3.21
Glomerular hyperfiltration: a new marker of metabolic risk. Kidney Int (2007) 3.17
Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A (1966) 3.16
Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13
Differentiation of T cells induced by preparations from thymus and by nonthymic agents. J Exp Med (1973) 3.12
Neutralizing monoclonal antibodies to the AIDS virus. AIDS (1988) 3.06
Platelet factor 4 is chemotactic for neutrophils and monocytes. Proc Natl Acad Sci U S A (1981) 3.03
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export. EMBO J (1998) 3.02
Titin: major myofibrillar components of striated muscle. Proc Natl Acad Sci U S A (1979) 2.96
Regeneration of amino acids from thiazolinones formed in the Edman degradation. Anal Biochem (1975) 2.86
Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival. J Virol (1997) 2.81
Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell (1997) 2.66
Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial. Diabetes Care (2000) 2.61
Patterns of cigarette smoking among Hispanics in the United States: results from HHANES 1982-84. Am J Public Health (1990) 2.52
Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. Genetics (1999) 2.50
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell (1996) 2.42
Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysis. Proc Natl Acad Sci U S A (1999) 2.33
Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol (1994) 2.18
Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses. J Clin Invest (1994) 2.14
Purification and properties of bovine thymosin. Ann N Y Acad Sci (1975) 2.08
Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron (1995) 2.08
Validation of an arsenic sequential extraction method for evaluating mobility in sediments. Environ Sci Technol (2001) 2.05
The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus. J Biol Chem (1979) 2.03
Morbidity and mortality analysis of 200 treatments with cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy using the coliseum technique. Ann Surg Oncol (1999) 2.02
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing. Mol Cell Biol (1987) 2.00
Pseudomyxoma peritonei syndrome. Adv Surg (1996) 1.99
Malakoplakia. J Pathol (1983) 1.98
Determination of the 3' terminal nucleotide of DNA fragments. Nucleic Acids Res (1975) 1.97
Sarcomas in north west England: I. Histopathological peer review. Br J Cancer (1991) 1.95
Chemical two-photon uncaging: a novel approach to mapping glutamate receptors. Neuron (1997) 1.91
Reconciliation of international administrative coding systems for comparison of colorectal surgery outcome. Colorectal Dis (2014) 1.91
Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Proc Natl Acad Sci U S A (1981) 1.90
Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation. J Clin Invest (1995) 1.89
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms. J Biol Chem (1994) 1.88
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile. Immunol Lett (1996) 1.87
p-alkoxybenzyl alcohol resin and p-alkoxybenzyloxycarbonylhydrazide resin for solid phase synthesis of protected peptide fragments. J Am Chem Soc (1973) 1.87
Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation. J Hepatol (1995) 1.87
Role of neuropathy and high foot pressures in diabetic foot ulceration. Diabetes Care (1998) 1.83
Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies. Teratology (2000) 1.78
Isogeneic lymphocyte interaction: recognition of self antigens by cells of the neonatal thymus. Proc Natl Acad Sci U S A (1970) 1.78
Neutralization of HTLV-III/LAV replication by antiserum to thymosin alpha 1. Science (1986) 1.75
Ontogenesis of cell-mediated immunity in murine thymocytes and spleen cells and its acceleration by thymosin, a thymic hormone. J Immunol (1971) 1.73
Psychotic disorders in urban areas: an overview of the Study on Low Prevalence Disorders. Aust N Z J Psychiatry (2000) 1.71
Influenza: response of T-cell lymphopenia to thymosin. N Engl J Med (1976) 1.69
Thymosin activity in patients with cellular immunodeficiency. N Engl J Med (1975) 1.67
Complete covalent structure of a human IgA1 immunoglobulin. Science (1976) 1.67
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol Biol Cell (1999) 1.66
Translational research in cancer genetics: the road less traveled. Public Health Genomics (2009) 1.65
Isolation and characterization of two linked mouse U1b small nuclear RNA genes. Nucleic Acids Res (1983) 1.63
Proliferative and cytotoxic T cells to AIDS virus glycoproteins in chimpanzees immunized with a recombinant vaccinia virus expressing AIDS virus envelope glycoproteins. J Immunol (1987) 1.63
Influence of thymosin on cell-mediated and humoral immune responses in normal and in immunologically deficient mice. J Immunol (1970) 1.62
Purification and characterization of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies. J Biol Chem (1981) 1.61
Effects of cisapride on QT interval in children. J Pediatr (1998) 1.59
Characterization of the Erwinia carotovora pelB gene and its product pectate lyase. J Bacteriol (1987) 1.57
Instability of antibiotic resistance in a strain of Staphylococcus epidermidis isolated from an outbreak of prosthetic valve endocarditis. J Infect Dis (1985) 1.56
Purification and biochemical characterization of CP4 (SP-D), a collagenous surfactant-associated protein. Biochemistry (1989) 1.55
Primary structure of neocarzinostatin, an antitumor protein. Science (1972) 1.55
Localisation of aluminium by histochemical and electron probe x-ray microanalytical techniques in bone tissue of cases of renal osteodystrophy. J Clin Pathol (1982) 1.55
T-cell responses to human AIDS virus in macaques immunized with recombinant vaccinia viruses. Nature (1986) 1.55
In vitro stimulation of murine spleen cells using a microculture system and a multiple automated sample harvester. J Immunol Methods (1973) 1.54
Determination of the primary structure of cholera toxin B subunit. J Biol Chem (1977) 1.53
Hyperbilirubinemia after cardiac operation. Incidence, risk factors, and clinical significance. J Thorac Cardiovasc Surg (1994) 1.52
Case report: portal vein thrombosis associated with hereditary protein C deficiency: a report of two cases. J Gastroenterol Hepatol (1999) 1.52
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A double-blind randomized controlled trial of oral misoprostol and intramuscular syntometrine in the management of the third stage of labor. Gynecol Obstet Invest (2006) 1.52
Molecular structure of pulmonary surfactant protein D (SP-D). J Biol Chem (1994) 1.51
Surfactant protein D is a divalent cation-dependent carbohydrate-binding protein. J Biol Chem (1990) 1.51
Drug- and toxin-induced rhabdomyolysis. Ann Emerg Med (1989) 1.51
Thymosin beta4 accelerates wound healing. J Invest Dermatol (1999) 1.50
Avian reticuloendotheliosis virus: identification of the hematopoietic target cell for transformation. Cell (1981) 1.49
Surfactant protein-D modulates interaction of Pneumocystis carinii with alveolar macrophages. J Lab Clin Med (1995) 1.49
Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A. Am J Physiol (1996) 1.49
Acute enlargement and subsequent rupture of an abdominal aortic aneurysm in a patient receiving chemotherapy for pancreatic carcinoma. J Vasc Surg (2000) 1.48
Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT1 gene. Mol Cell Biol (1986) 1.48
Serum amylase, isoamylase, and lipase in the acute abdomen. Their diagnostic value for acute pancreatitis. J Clin Gastroenterol (1989) 1.47
Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. FASEB J (1997) 1.46