Published in Autophagy on November 13, 2015
NF-kB activation induced by chloroquine requires autophagosome, p62, and JNK signaling and promotes tumor cell resistance. J Biol Chem (2017) 0.76
Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol (2016) 0.76
DNA Damage Response and Autophagy: A Meaningful Partnership. Front Genet (2016) 0.75
Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival. Genes Dis (2016) 0.75
Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair. Pigment Cell Melanoma Res (2017) 0.75
Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo. Redox Biol (2016) 0.75
Impact on Autophagy and Ultraviolet B Induced Responses of Treatment with the MTOR Inhibitors Rapamycin, Everolimus, Torin 1, and pp242 in Human Keratinocytes. Oxid Med Cell Longev (2017) 0.75
Adaptor Protein p62 Promotes Skin Tumor Growth and Metastasis and is Induced by UVA Radiation. J Biol Chem (2017) 0.75
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell (2004) 31.38
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem (2007) 21.73
Defining the role of mTOR in cancer. Cancer Cell (2007) 21.63
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol (2005) 18.23
Genome maintenance mechanisms for preventing cancer. Nature (2001) 16.17
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem (2004) 14.93
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell (2008) 14.80
Autophagy and the integrated stress response. Mol Cell (2010) 11.21
Autophagy suppresses tumorigenesis through elimination of p62. Cell (2009) 9.95
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell (1998) 9.41
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev (2007) 6.35
Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Mol Cell (2000) 6.26
Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer (2012) 6.14
Sequential assembly of the nucleotide excision repair factors in vivo. Mol Cell (2001) 5.38
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. Cancer Cell (2008) 4.48
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res (2007) 4.48
UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell (2005) 3.85
Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids. Biotechniques (2010) 3.62
The dynamic nature of autophagy in cancer. Genes Dev (2011) 3.57
A common set of gene regulatory networks links metabolism and growth inhibition. Mol Cell (2004) 3.37
mTOR and cancer therapy. Oncogene (2006) 3.07
Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. EMBO J (1994) 2.94
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell (1999) 2.90
The comings and goings of nucleotide excision repair factors on damaged DNA. EMBO J (2003) 2.89
Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell (2011) 2.77
Regulation of DNA repair by ubiquitylation. Nat Rev Mol Cell Biol (2006) 2.73
Autophagy in human health and disease. N Engl J Med (2013) 2.73
Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat Rev Cancer (2005) 2.69
Autophagy in malignant transformation and cancer progression. EMBO J (2015) 2.67
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet (2009) 2.48
Shining a light on xeroderma pigmentosum. J Invest Dermatol (2012) 2.33
Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair. J Med Genet (2010) 2.14
Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer (2011) 2.14
TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene (2010) 1.81
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer. BMC Cancer (2012) 1.70
HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro. Mol Cell Biol (1996) 1.63
Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis. Nature (2001) 1.55
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Powerful skin cancer protection by a CPD-photolyase transgene. Curr Biol (2005) 1.39
ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol (2014) 1.35
Redundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcription. Nucleic Acids Res (2010) 1.35
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C. Proc Natl Acad Sci U S A (2010) 1.30
Regulation of excision repair cross-complementation group 1 by Snail contributes to cisplatin resistance in head and neck cancer. Clin Cancer Res (2010) 1.30
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Cancer Discov (2014) 1.28
Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A (2014) 1.28
Xeroderma pigmentosum genes: functions inside and outside DNA repair. Carcinogenesis (2008) 1.11
Roles of Rad23 protein in yeast nucleotide excision repair. Nucleic Acids Res (2004) 1.09
Autophagy and genomic integrity. Cell Death Differ (2013) 1.07
Autophagy controls p38 activation to promote cell survival under genotoxic stress. J Biol Chem (2012) 1.03
Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proc Natl Acad Sci U S A (2015) 1.02
Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis (1998) 0.99
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res (2014) 0.97
Autophagy in cancer. F1000Prime Rep (2015) 0.96
p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair. Nucleic Acids Res (2012) 0.95
Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion. Mol Cancer Res (2015) 0.93
UV-DDB: a molecular machine linking DNA repair with ubiquitination. DNA Repair (Amst) (2009) 0.93
ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4. EMBO Rep (2009) 0.92
Ultraviolet radiation-induced non-melanoma skin cancer: Regulation of DNA damage repair and inflammation. Genes Dis (2014) 0.90
Dual role of SIRT1 in UVB-induced skin tumorigenesis. Oncogene (2014) 0.89
Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice. Carcinogenesis (1991) 0.88
Targeting protective autophagy exacerbates UV-triggered apoptotic cell death. Int J Mol Sci (2012) 0.88
Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 expression. Oncol Rep (2014) 0.87
Cyclobutane-type pyrimidine photodimer formation and induction of ornithine decarboxylase in human skin fibroblasts after UV irradiation. J Invest Dermatol (1988) 0.87
SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors. Cell Cycle (2015) 0.87
p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG. DNA Repair (Amst) (2012) 0.84
Molecular regulation of UV-induced DNA repair. Photochem Photobiol (2015) 0.83