Published in Nat Rev Cancer on April 26, 2012
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Autophagy as a modulator and target in prostate cancer. Nat Rev Urol (2014) 1.13
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Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene (2014) 1.09
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Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma. Cell Death Differ (2014) 1.05
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Immunogenic cell death in radiation therapy. Oncoimmunology (2013) 1.04
Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy. Redox Biol (2014) 1.04
Autophagy controls p38 activation to promote cell survival under genotoxic stress. J Biol Chem (2012) 1.03
Tumor suppression and promotion by autophagy. Biomed Res Int (2014) 1.02
Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma. Cancer Discov (2015) 1.02
Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3. Cell Rep (2016) 1.01
The functional and pathologic relevance of autophagy proteases. J Clin Invest (2015) 1.01
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes Dev (2014) 1.01
Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy. Leukemia (2013) 1.00
Autophagy in inflammation, infection, neurodegeneration and cancer. Int Immunopharmacol (2013) 1.00
The MAGE protein family and cancer. Curr Opin Cell Biol (2015) 1.00
MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell. Autophagy (2014) 0.99
Targeting autophagy in breast cancer. World J Clin Oncol (2014) 0.99
Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression. Cancer Cell (2014) 0.99
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers. Autophagy (2014) 0.99
Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells. Autophagy (2014) 0.98
KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models. Oncotarget (2015) 0.98
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol (2013) 0.97
Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation. J Cell Sci (2014) 0.97
Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis. Front Immunol (2014) 0.96
The importance of autophagy regulation in breast cancer development and treatment. Biomed Res Int (2014) 0.95
Autophagy, Metabolism, and Cancer. Clin Cancer Res (2015) 0.95
A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin. Sci Transl Med (2014) 0.95
Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers. Cancer Discov (2014) 0.94
PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma. Oncotarget (2015) 0.94
Autophagy-mediated regulation of macrophages and its applications for cancer. Autophagy (2013) 0.94
Chronic mTOR activation promotes cell survival in Merkel cell carcinoma. Cancer Lett (2013) 0.94
Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer. Trends Cell Biol (2013) 0.94
Autophagy in breast cancer and its implications for therapy. Am J Cancer Res (2013) 0.94
COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs. Front Oncol (2013) 0.94
Autophagy and its effects: making sense of double-edged swords. PLoS Biol (2014) 0.94
miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy. Oncotarget (2015) 0.93
Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion. Mol Cancer Res (2015) 0.93
Autophagy modulation as a target for anticancer drug discovery. Acta Pharmacol Sin (2013) 0.93
Modulation of the autophagy pathway by human tumor viruses. Semin Cancer Biol (2013) 0.93
Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem (2015) 0.92
mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions. Mol Biol Int (2014) 0.92
Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation. Cell Death Dis (2014) 0.92
Autophagy: a potential therapeutic target in lung diseases. Am J Physiol Lung Cell Mol Physiol (2013) 0.92
Measuring autophagy in stressed cells. Methods Mol Biol (2015) 0.92
Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death. J Invest Dermatol (2015) 0.92
Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway. Mol Carcinog (2015) 0.92
Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells. Mol Oncol (2015) 0.92
Coffee induces autophagy in vivo. Cell Cycle (2014) 0.91
The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res (2013) 0.91
Tumor Protein 53-Induced Nuclear Protein 1 Enhances p53 Function and Represses Tumorigenesis. Front Genet (2013) 0.91
Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma. Oncotarget (2015) 0.91
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Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell (2005) 17.81
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 16.67
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Autophagy: renovation of cells and tissues. Cell (2011) 11.59
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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest (2007) 9.33
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An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. Science (2010) 6.47
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Autophagy-deficient mice develop multiple liver tumors. Genes Dev (2011) 4.64
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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med (2011) 3.89
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Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent. Proc Natl Acad Sci U S A (2011) 2.73
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Concern Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27. Proc Natl Acad Sci U S A (2003) 2.52
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Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer (2010) 1.63
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Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis. Oncogene (2010) 1.40
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