Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition.

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Published in Mol Ther on November 19, 2015

Authors

Sultan Abdul-Jawad1, Beatrice Ondondo1, Andy van Hateren2, Andrew Gardner1, Tim Elliott2, Bette Korber3, Tomáš Hanke4

Author Affiliations

1: The Jenner Institute, University of Oxford, Oxford, UK.
2: Faculty of Medicine and Institute for Life Science, University of Southampton, Southampton, UK.
3: Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, USA; The New Mexico Consortium, Los Alamos, New Mexico, USA.
4: The Jenner Institute, University of Oxford, Oxford, UK; International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: tomas.hanke@ndm.ox.ac.uk.

Associated clinical trials:

Safety, Tolerability, and Immunogenicity Study of Homologous Ad26 Mosaic Vector Vaccine Regimens or Heterologous Ad26 Mosaic and MVA Mosaic Vector Vaccine Regimens With Glycoprotein 140 (gp140) for Human Immunodeficiency Virus (HIV) Prevention | NCT02315703

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