Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

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Published in Mol Ther on October 31, 2013

Authors

Nicola Borthwick1, Tina Ahmed1, Beatrice Ondondo2, Peter Hayes3, Annie Rose4, Umar Ebrahimsa4, Emma-Jo Hayton4, Antony Black5, Anne Bridgeman1, Maximillian Rosario6, Adrian Vs Hill7, Eleanor Berrie8, Sarah Moyle8, Nicole Frahm9, Josephine Cox3, Stefano Colloca10, Alfredo Nicosia11, Jill Gilmour3, Andrew J McMichael12, Lucy Dorrell12, Tomáš Hanke13

Author Affiliations

1: The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, UK; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, The John Radcliffe, Oxford, UK.
2: The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, UK.
3: IAVI Human Immunology Laboratory, Imperial College, London, UK.
4: Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, University of Oxford, Churchill Hospital, Oxford, UK.
5: Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, University of Oxford, Churchill Hospital, Oxford, UK; Current address: Institut Pasteur du Laos, Vientiane, Laos People's Democratic Republic.
6: MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, The John Radcliffe, Oxford, UK; Current address: Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, 6-096 Katz Centre for Health Research, Edmonton, Alberta, Canada.
7: The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, UK; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, University of Oxford, Churchill Hospital, Oxford, UK; Clinical Biomanufacturing Facility, University of Oxford, Churchill Hospital, Oxford, UK.
8: Clinical Biomanufacturing Facility, University of Oxford, Churchill Hospital, Oxford, UK.
9: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
10: Okairos, Rome, Italy.
11: Okairos, Rome, Italy; CEINGE, Naples, Italy; Department of Biochemistry and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
12: MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, The John Radcliffe, Oxford, UK.
13: The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford, UK; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, The John Radcliffe, Oxford, UK; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, University of Oxford, Churchill Hospital, Oxford, UK; Clinical Biomanufacturing Facility, University of Oxford, Churchill Hospital, Oxford, UK. Electronic address: tomas.hanke@ndm.ox.ac.uk.

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