HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor.

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res (1994) 8.57

Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol (2002) 6.68

Exploring RNA transcription and turnover in vivo by using click chemistry. Proc Natl Acad Sci U S A (2008) 3.34

Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res (2002) 3.32

Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation (2005) 3.12

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation (2005) 2.79

Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp. Mol Cell (2007) 2.20

Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J Clin Invest (2001) 2.19

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway. J Mol Biol (2005) 2.04

Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress. J Biol Chem (2000) 1.98

Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie (2002) 1.71

Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc Res (2007) 1.63

Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation (1998) 1.57

Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2. Hypertension (2005) 1.49

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence. Oncogene (2011) 1.45

Physiological roles of the permeability transition pore. Circ Res (2012) 1.40

An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. Int J Mol Sci (2012) 1.37

Angiotensin II, NADPH oxidase, and redox signaling in the vasculature. Antioxid Redox Signal (2012) 1.27

The IP(3) receptor-mitochondria connection in apoptosis and autophagy. Biochim Biophys Acta (2010) 1.22

Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress. J Biol Chem (2004) 1.21

Role of Herp in the endoplasmic reticulum stress response. Genes Cells (2004) 1.19

Turning point in apoptosis/necrosis induced by hydrogen peroxide. Free Radic Res (2006) 1.18

Mitochondrial control of cell death induced by hyperosmotic stress. Apoptosis (2007) 1.15

Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes. Biochim Biophys Acta (2010) 1.14

Hydrogen peroxide as a signaling molecule. Antioxid Redox Signal (2011) 1.14

Local regulation of arterial L-type calcium channels by reactive oxygen species. Circ Res (2010) 1.13

NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells. J Biol Chem (2008) 1.08

Xestospongin B, a competitive inhibitor of IP3-mediated Ca2+ signalling in cultured rat myotubes, isolated myonuclei, and neuroblastoma (NG108-15) cells. FEBS Lett (2005) 1.05

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy. Cardiovasc Res (2011) 1.03

The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway. FEBS Lett (2000) 0.97

Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner. J Biol Chem (2010) 0.96

The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease. J Biol Chem (2009) 0.96

Endoplasmic reticulum stress contributes to aortic stiffening via proapoptotic and fibrotic signaling mechanisms. Hypertension (2013) 0.96

The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins. Hum Mol Genet (2011) 0.94

Green tea attenuates angiotensin II-induced cardiac hypertrophy in rats by modulating reactive oxygen species production and the Src/epidermal growth factor receptor/Akt signaling pathway. J Nutr (2008) 0.93

Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. J Mol Cell Cardiol (2014) 0.92

Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death. Biochim Biophys Acta (2013) 0.91

Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance. Cell Cycle (2014) 0.87

Hyperosmotic stress-dependent NFkappaB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes. FEBS Lett (2006) 0.86

A cytosolic source of calcium unveiled by hydrogen peroxide with relevance for epithelial cell death. Cell Death Differ (2004) 0.84

Heat stress induces apoptosis through a Ca²⁺-mediated mitochondrial apoptotic pathway in human umbilical vein endothelial cells. PLoS One (2014) 0.83

Reciprocal effects of glucose on the process of cell death induced by calcium ionophore or H2O2 in rat lymphocytes. Toxicology (2006) 0.82

The mitochondrial permeability transition pore (PTP) - an example of multiple molecular exaptation? Biochim Biophys Acta (2012) 0.81

Ube2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recovery. J Cell Sci (2014) 0.81

Herp depletion protects from protein aggregation by up-regulating autophagy. Biochim Biophys Acta (2013) 0.81

ER-stress-inducible Herp, facilitates the degradation of immature nicastrin. Biochim Biophys Acta (2011) 0.79

Superoxide activates mTOR-eIF4E-Bax route to induce enhanced apoptosis in leukemic cells. Apoptosis (2014) 0.79

Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes. Cell Commun Signal (2014) 0.79

1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline. Neurochem Int (2008) 0.78

Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 Cells. Int J Biomed Sci (2009) 0.77