Published in Antioxid Redox Signal on June 11, 2012
Reperfusion injury and reactive oxygen species: The evolution of a concept. Redox Biol (2015) 1.19
Renal autoregulation in health and disease. Physiol Rev (2015) 1.18
Strategies to increase nitric oxide signalling in cardiovascular disease. Nat Rev Drug Discov (2015) 1.18
Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research. Antioxid Redox Signal (2013) 1.14
A paradigm shift for local blood flow regulation. J Appl Physiol (1985) (2013) 1.14
Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases. Am J Physiol Regul Integr Comp Physiol (2013) 1.00
Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. J Mol Cell Cardiol (2014) 0.92
The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance. Front Physiol (2014) 0.89
Molecular mechanisms of diabetic retinopathy: potential therapeutic targets. Middle East Afr J Ophthalmol (2015) 0.88
Bang-bang model for regulation of local blood flow. Microcirculation (2013) 0.87
NOX signaling in molecular cardiovascular mechanisms involved in the blood pressure homeostasis. Front Physiol (2015) 0.84
Hemoglobin-associated oxidative stress in the pericardial compartment of postoperative cardiac surgery patients. Lab Invest (2014) 0.83
Suppression of TGF-β1/Smad signaling pathway by sesamin contributes to the attenuation of myocardial fibrosis in spontaneously hypertensive rats. PLoS One (2015) 0.82
Testosterone delays vascular smooth muscle cell senescence and inhibits collagen synthesis via the Gas6/Axl signaling pathway. Age (Dordr) (2016) 0.78
ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells. Am J Physiol Heart Circ Physiol (2015) 0.78
Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. PLoS One (2014) 0.78
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis. Biosci Rep (2016) 0.77
Obligatory role for GPER in cardiovascular aging and disease. Sci Signal (2016) 0.77
Andrographolide, a Novel NF-κB Inhibitor, Inhibits Vascular Smooth Muscle Cell Proliferation and Cerebral Endothelial Cell Inflammation. Zhonghua Minguo Xin Zang Xue Hui Za Zhi (2014) 0.77
PGC-1α limits angiotensin II-induced rat vascular smooth muscle cells proliferation via attenuating NOX1-mediated generation of reactive oxygen species. Biosci Rep (2015) 0.77
Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species. Cardiovasc Res (2015) 0.77
ROS and endothelial nitric oxide synthase (eNOS)-dependent trafficking of angiotensin II type 2 receptor begets neuronal NOS in cardiac myocytes. Basic Res Cardiol (2015) 0.77
Role of homocysteinylation of ACE in endothelial dysfunction of arteries. Am J Physiol Heart Circ Physiol (2014) 0.76
Sustained elevation of NF-κB activity sensitizes offspring of maternal inflammation to hypertension via impairing PGC-1α recovery. Sci Rep (2016) 0.76
Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes. J Cardiovasc Pharmacol (2015) 0.76
Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway. BMC Complement Altern Med (2015) 0.76
The anti-ageing hormone klotho induces Nrf2-mediated antioxidant defences in human aortic smooth muscle cells. J Cell Mol Med (2016) 0.76
Kolaviron, Biflavonoid Complex from the Seed of Garcinia kola Attenuated Angiotensin II- and Lypopolysaccharide-induced Vascular Smooth Muscle Cell Proliferation and Nitric Oxide Production. Pharmacognosy Res (2016) 0.75
CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression. Redox Biol (2017) 0.75
Vascular smooth muscle-specific deletion of the leptin receptor attenuates leptin-induced alterations in vascular relaxation. Am J Physiol Regul Integr Comp Physiol (2016) 0.75
Administration of bovine casein-derived peptide prevents cognitive decline in Alzheimer disease model mice. PLoS One (2017) 0.75
Relationship between NOX4 level and angiotensin II signaling in Gitelman's syndrome. Implications with hypertension. Int J Clin Exp Med (2015) 0.75
Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II-mediated hypertension. Br J Pharmacol (2016) 0.75
Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARα and RXR/PPARγ interactions. Antioxid Redox Signal (2015) 0.75
Rotenone-stimulated superoxide release from mitochondrial complex I acutely augments L-type Ca2+ current in A7r5 aortic smooth muscle cells. Am J Physiol Heart Circ Physiol (2016) 0.75
The Angiotensin-(1-7)/Mas Axis Counteracts Angiotensin II-Dependent and -Independent Pro-inflammatory Signaling in Human Vascular Smooth Muscle Cells. Front Pharmacol (2016) 0.75
Resveratrol Improved Flow-Mediated Outward Arterial Remodeling in Ovariectomized Rats with Hypertrophic Effect at High Dose. PLoS One (2016) 0.75
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor. Free Radic Biol Med (2015) 0.75
Angiotensin II-Induced Early and Late Inflammatory Responses Through NOXs and MAPK Pathways. Inflammation (2016) 0.75
The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side. Int J Mol Sci (2017) 0.75
Oxygen Toxicity and Special Operations Forces Diving: Hidden and Dangerous. Front Psychol (2017) 0.75
AT1 receptor signaling pathways in the cardiovascular system. Pharmacol Res (2017) 0.75
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res (1994) 8.57
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol (2006) 7.84
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest (1996) 6.38
Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res (2001) 4.22
Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Regul Integr Comp Physiol (2003) 3.63
Nox proteins in signal transduction. Free Radic Biol Med (2009) 3.47
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev (2000) 3.40
Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res (2002) 3.32
Therapeutic targeting of mitochondrial superoxide in hypertension. Circ Res (2010) 3.16
Superoxide anion radical (O2-.), superoxide dismutases, and related matters. J Biol Chem (1997) 3.05
Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ Res (2009) 2.83
Subcellular localization of Nox4 and regulation in diabetes. Proc Natl Acad Sci U S A (2009) 2.73
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Free Radic Biol Med (2008) 2.68
p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem (1996) 2.56
Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest (2009) 2.49
Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3. Circ Res (2007) 2.47
Redox signaling in hypertension. Cardiovasc Res (2006) 2.37
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Circ Res (2002) 2.27
NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol (2008) 2.22
c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2003) 2.16
Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress. J Hypertens (2005) 2.01
The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation. Cardiovasc Res (2010) 1.79
Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid Redox Signal (2009) 1.71
NADPH oxidases: new kids on the block. Cardiovasc Res (2006) 1.57
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56
Regulation of the phagocyte NADPH oxidase by Rac GTPase. Antioxid Redox Signal (2006) 1.48
NADPH oxidase 4 is an oncoprotein localized to mitochondria. Cancer Biol Ther (2010) 1.38
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci (2011) 1.31
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. Am J Physiol Heart Circ Physiol (2010) 1.31
Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. Hypertension (1999) 1.28
Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol (2008) 1.28
p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II. Arterioscler Thromb Vasc Biol (2004) 1.26
Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species. Mol Biol Cell (2010) 1.25
The role of Rho protein signaling in hypertension. Nat Rev Cardiol (2010) 1.23
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens (2004) 1.23
G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor. J Biol Chem (2005) 1.19
Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases. Basic Clin Pharmacol Toxicol (2011) 1.18
Protein tyrosine phosphorylation and protein tyrosine nitration in redox signaling. Antioxid Redox Signal (2008) 1.18
Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts. Arterioscler Thromb Vasc Biol (2011) 1.18
Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways. Circ Res (2007) 1.16
A comparison of thiol peroxidase mechanisms. Antioxid Redox Signal (2010) 1.14
Microparticles are vectors of paradoxical information in vascular cells including the endothelium: role in health and diseases. Pharmacol Rep (2008) 1.13
Redox regulation of protein kinases as a modulator of vascular function. Antioxid Redox Signal (2011) 1.12
Cell signaling of angiotensin II on vascular tone: novel mechanisms. Curr Hypertens Rep (2011) 1.11
Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein. Arterioscler Thromb Vasc Biol (2007) 1.11
Reversible oxidative modification: implications for cardiovascular physiology and pathophysiology. Trends Cardiovasc Med (2010) 1.08
The role of p66Shc deletion in age-associated arterial dysfunction and disease states. J Appl Physiol (1985) (2008) 1.08
Oxidative stress and lectin-like ox-LDL-receptor LOX-1 in atherogenesis and tumorigenesis. Antioxid Redox Signal (2011) 1.07
Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR. Circ Res (2008) 1.06
Pathophysiological regulation of the AT1-receptor and implications for vascular disease. J Hypertens Suppl (2006) 1.05
Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration. Cardiovasc Res (2011) 1.05
Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation. Antioxid Redox Signal (2010) 1.05
The angiotensin II type 2 receptor in cardiovascular disease. J Renin Angiotensin Aldosterone Syst (2009) 1.03
Differential vascular functions of Nox family NADPH oxidases. Curr Opin Lipidol (2008) 1.02
New insight into the Nox4 subcellular localization in HEK293 cells: first monoclonal antibodies against Nox4. Biochimie (2010) 1.02
Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation. Am J Hypertens (2005) 1.01
Signaling mechanisms of angiotensin II in regulating vascular senescence. Ageing Res Rev (2008) 0.98
Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis. FASEB J (2011) 0.97
Vascular signaling through cholesterol-rich domains: implications in hypertension. Curr Opin Nephrol Hypertens (2007) 0.97
Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR. J Am Soc Hypertens (2011) 0.97
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension (2008) 0.96
NOX isoforms and reactive oxygen species in vascular health. Mol Interv (2011) 0.96
Highly reactive oxygen species: detection, formation, and possible functions. Cell Mol Life Sci (2011) 0.95
Role of renin-angiotensin system in inflammation, immunity and aging. Curr Pharm Des (2012) 0.95
Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. Cardiovasc Ther (2012) 0.94
Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress. Hypertension (2010) 0.94
Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme. J Clin Biochem Nutr (2011) 0.94
Superoxide anion and hydrogen peroxide-induced signaling and damage in angiotensin II and aldosterone action. Biol Chem (2010) 0.93
Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Can J Physiol Pharmacol (2003) 0.92
Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR. Am J Physiol Heart Circ Physiol (2010) 0.90
Protein disulfide isomerase overexpression in vascular smooth muscle cells induces spontaneous preemptive NADPH oxidase activation and Nox1 mRNA expression: effects of nitrosothiol exposure. Arch Biochem Biophys (2009) 0.88
Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: role of PDGFR. Cardiovasc Res (2011) 0.88
Sulfhydryl angiotensin-converting enzyme inhibitor promotes endothelial cell survival through nitric-oxide synthase, fibroblast growth factor-2, and telomerase cross-talk. J Pharmacol Exp Ther (2009) 0.88
Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1. PLoS One (2010) 0.87
Redox active secondary metabolites. Curr Opin Chem Biol (2010) 0.85
SOD isoforms and signaling in blood vessels: evidence for the importance of ROS compartmentalization. Arterioscler Thromb Vasc Biol (2005) 0.83
Regulation of Angiotensin II receptor signaling by cysteine modification of NF-κB. Nitric Oxide (2010) 0.78
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care (2008) 3.07
Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens (Greenwich) (2013) 2.94
Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension. J Hypertens (2014) 2.82
Redox signaling in hypertension. Cardiovasc Res (2006) 2.37
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways. Hypertension (2006) 2.12
The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part II - therapy. Can J Cardiol (2005) 2.03
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2007) 2.01
Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms. Clin Sci (Lond) (2006) 1.87
The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2012) 1.86
Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension (2002) 1.81
Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients. Hypertension (2006) 1.80
NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis. Circulation (2013) 1.78
Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system. Am J Hypertens (2004) 1.67
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy. Can J Cardiol (2006) 1.67
Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction. Circulation (2004) 1.65
Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice. J Hypertens (2007) 1.65
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1--blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2009) 1.64
Neonatal oxygen exposure in rats leads to cardiovascular and renal alterations in adulthood. Hypertension (2008) 1.64
Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. Hypertension (2012) 1.63
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ Res (2008) 1.59
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells. Hypertension (2007) 1.58
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56
Oxidative stress and hypertension: current concepts. Curr Hypertens Rep (2010) 1.54
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2007) 1.49
Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice. Cell Metab (2009) 1.47
Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Hypertension (2005) 1.47
Human cord blood CD133+ cells exacerbate ischemic acute kidney injury in mice. Nephrol Dial Transplant (2012) 1.46
The World Hypertension League and International Society of Hypertension call on governments, nongovernmental organizations, and the food industry to work to reduce dietary sodium. J Clin Hypertens (Greenwich) (2014) 1.44
The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2010) 1.44
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapy. Can J Cardiol (2009) 1.42
Comparison of angiotensin-converting enzyme (ACE), neutral endopeptidase (NEP) and dual ACE/NEP inhibition on blood pressure and resistance arteries of deoxycorticosterone acetate-salt hypertensive rats. J Hypertens (2002) 1.42
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part I--Blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2006) 1.42
Microparticles: biomarkers and beyond. Clin Sci (Lond) (2013) 1.41
Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients. Hypertension (2006) 1.40
The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2011) 1.38
Myocyte growth, repair, and oxidative stress following pediatric heart transplantation. Pediatr Transplant (2014) 1.37
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ Res (2004) 1.36
Molecular mechanisms of hypertension--reactive oxygen species and antioxidants: a basic science update for the clinician. Can J Cardiol (2012) 1.36
Oxidative stress, Noxs, and hypertension: experimental evidence and clinical controversies. Ann Med (2012) 1.33
A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme. Pharmacol Rev (2012) 1.31
From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. Am J Physiol Heart Circ Physiol (2004) 1.28
NADPH oxidases, reactive oxygen species, and the kidney: friend and foe. J Am Soc Nephrol (2013) 1.27
The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2008) 1.25
Cellular biomarkers of endothelial health: microparticles, endothelial progenitor cells, and circulating endothelial cells. J Am Soc Hypertens (2012) 1.25
Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury. Arterioscler Thromb Vasc Biol (2005) 1.24
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens (2004) 1.23
Role of magnesium in hypertension. Arch Biochem Biophys (2006) 1.22
Molecular mechanisms of hypertension: role of Nox family NADPH oxidases. Curr Opin Nephrol Hypertens (2009) 1.21
ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension. Hypertension (2003) 1.20
Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases. Basic Clin Pharmacol Toxicol (2011) 1.18
Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts. Arterioscler Thromb Vasc Biol (2011) 1.18
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. Hypertension (2003) 1.15
Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research. Antioxid Redox Signal (2013) 1.14
Vascular smooth muscle cell differentiation to an osteogenic phenotype involves TRPM7 modulation by magnesium. Hypertension (2010) 1.14
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension (2002) 1.13
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes. Clin Sci (Lond) (2013) 1.13
Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats. J Cardiovasc Pharmacol (2004) 1.12
Angiotensin II and the vascular phenotype in hypertension. Expert Rev Mol Med (2011) 1.11
Cell signaling of angiotensin II on vascular tone: novel mechanisms. Curr Hypertens Rep (2011) 1.11
Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells. Nephrol Dial Transplant (2009) 1.10
Selective mineralocorticoid receptor blocker eplerenone reduces resistance artery stiffness in hypertensive patients. Hypertension (2008) 1.10
c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats. Hypertension (2005) 1.10
Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice. Am J Physiol Heart Circ Physiol (2006) 1.10
Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension. Hypertension (2003) 1.09
Effect of peroxisome proliferator-activated receptor-alpha and -gamma activators on vascular remodeling in endothelin-dependent hypertension. Arterioscler Thromb Vasc Biol (2003) 1.09
A new look at the renin-angiotensin system--focusing on the vascular system. Peptides (2011) 1.08
Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol (2008) 1.08
The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part I - blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2010) 1.07
Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR. Circ Res (2008) 1.06
Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats. Am J Hypertens (2002) 1.05
Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5. Clin Sci (Lond) (2011) 1.05
The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2008) 1.05
The 2001 Canadian recommendations for the management of hypertension: Part one--Assessment for diagnosis, cardiovascular risk, causes and lifestyle modification. Can J Cardiol (2002) 1.02
Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation. Am J Hypertens (2005) 1.01
Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats. J Hypertens (2005) 1.01
Increased systemic inflammation and oxidative stress in patients with worsening congestive heart failure: improvement after short-term inotropic support. Clin Sci (Lond) (2006) 1.00
Vascular Nox4: a multifarious NADPH oxidase. Circ Res (2012) 0.99
alpha 8 Integrin overexpression in de-differentiated vascular smooth muscle cells attenuates migratory activity and restores the characteristics of the differentiated phenotype. Atherosclerosis (2007) 0.99
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension (2004) 0.99
Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice. Arterioscler Thromb Vasc Biol (2003) 0.98
Reactive oxygen species and vascular remodelling in hypertension: still alive. Can J Cardiol (2006) 0.98
Lipid rafts take center stage in endothelial cell redox signaling by death receptors. Hypertension (2005) 0.97
Vascular signaling through cholesterol-rich domains: implications in hypertension. Curr Opin Nephrol Hypertens (2007) 0.97
Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR. J Am Soc Hypertens (2011) 0.97
Angiotensin II and vascular injury. Curr Hypertens Rep (2014) 0.97
Microparticles induce cell cycle arrest through redox-sensitive processes in endothelial cells: implications in vascular senescence. J Am Heart Assoc (2012) 0.96