Published in Sci Rep on December 02, 2015
Distance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexes. Phys Chem Chem Phys (2016) 0.75
Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences. Sci Rep (2016) 0.75
Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 28.20
CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71
The serial cultivation of human diploid cell strains. Exp Cell Res (1961) 25.11
Telomeres shorten during ageing of human fibroblasts. Nature (1990) 23.97
Telomerase catalytic subunit homologs from fission yeast and human. Science (1997) 12.35
The RNA component of human telomerase. Science (1995) 9.86
Telomere length regulation. Annu Rev Biochem (1996) 6.98
Quadruplex DNA: sequence, topology and structure. Nucleic Acids Res (2006) 6.42
Inhibition of telomerase by G-quartet DNA structures. Nature (1991) 5.38
DNA tetraplex formation in the control region of c-myc. Nucleic Acids Res (1998) 4.09
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution. Nucleic Acids Res (2006) 3.87
Telomere maintenance as a target for anticancer drug discovery. Nat Rev Drug Discov (2002) 3.32
Telomeres: cancer to human aging. Annu Rev Cell Dev Biol (2006) 2.88
Flavonoids: promising anticancer agents. Med Res Rev (2003) 2.43
Targeting telomeres and telomerase. Biochimie (2007) 2.02
A novel K(+)-dependent DNA synthesis arrest site in a commonly occurring sequence motif in eukaryotes. J Biol Chem (1994) 1.90
Antioxidant and antiradical activities of flavonoids. J Agric Food Chem (2001) 1.74
Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur J Nutr (1999) 1.59
NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA. Biochemistry (1998) 1.45
Effect of DNA secondary structure on human telomerase activity. Biochemistry (1998) 1.43
Anti- and pro-oxidant activity of rutin and quercetin derivatives. J Pharm Pharmacol (2003) 1.40
G-quadruplexes: targets in anticancer drug design. ChemMedChem (2008) 1.21
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis. Food Chem Toxicol (2008) 1.20
Mutagenic activity of quercetin and related compounds. Science (1977) 1.18
Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I. Biochem J (2002) 1.00
Natural and synthetic G-quadruplex interactive berberine derivatives. Bioorg Med Chem Lett (2006) 0.96
The development of telomerase inhibitors: the G-quartet approach. Anticancer Drug Des (1999) 0.93
An overview of DNA and RNA bindings to antioxidant flavonoids. Cell Biochem Biophys (2007) 0.93
The interaction of quercetin with human serum albumin: a fluorescence spectroscopic study. Biochem Biophys Res Commun (2002) 0.92
Interaction of berberine, palmatine, coralyne, and sanguinarine to quadruplex DNA: a comparative spectroscopic and calorimetric study. Biochim Biophys Acta (2011) 0.90
Spectroscopic study on the binding of porphyrins to (G(4)T(4)G(4))4 parallel G-quadruplex. Biophys Chem (2010) 0.90
Recent advances in the development of telomerase inhibitors for the treatment of cancer. Expert Opin Investig Drugs (1999) 0.89
Telomerase inhibition as cancer therapy. Cancer Lett (2003) 0.89
Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. Prostate (2001) 0.87
Spectroscopic, molecular modeling, and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA. ACS Chem Biol (2012) 0.85
DNA G-quadruplexes, telomere-specific proteins and telomere-associated enzymes as potential targets for new anticancer drugs. Invest New Drugs (2000) 0.84
Spectroscopic studies of the interaction between quercetin and G-quadruplex DNA. Bioorg Med Chem Lett (2006) 0.83
Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer. J Nucleic Acids (2009) 0.82
Structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat: evidence for A-tetrad formation from NMR and molecular dynamics simulations. Org Biomol Chem (2003) 0.82
Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sister-chromatid exchanges. Mutagenesis (1986) 0.80
Probing the binding affinity of small-molecule natural products to the G-quadruplex in C-myc oncogene by electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom (2010) 0.80
The characterisation of flavone-DNA isoform interactions as a basis for anticancer drug development. Anticancer Res (2009) 0.79
Electrochemical investigation on interaction between DNA with quercetin and Eu-Qu3 complex. J Inorg Biochem (2004) 0.79
Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids. Food Chem Toxicol (2003) 0.79
Quercetin and DNA in solution: analysis of the dynamics of their interaction with a linear dichroism study. Int J Biol Macromol (1996) 0.76
Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines. PLoS One (2013) 0.76