Published in Development on December 01, 2015
Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway. Cell Death Dis (2017) 0.77
Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea. Sci Rep (2016) 0.76
Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity. Proc Natl Acad Sci U S A (2017) 0.75
BANCR: a cancer-related long non-coding RNA. Am J Cancer Res (2017) 0.75
Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A (1971) 31.05
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature (1986) 13.96
A landscape of driver mutations in melanoma. Cell (2012) 12.61
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev (2002) 10.06
The genetic landscape of the childhood cancer medulloblastoma. Science (2010) 8.34
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer (2010) 6.27
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell (2000) 6.14
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev (2001) 6.13
Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol Cell Biol (2001) 5.61
Vertebrate neural cell-fate determination: lessons from the retina. Nat Rev Neurosci (2001) 5.26
The SWI/SNF complex and cancer. Oncogene (2009) 5.05
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol (2001) 5.03
A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell (1994) 5.00
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res (2011) 4.91
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Cell fate determination in the vertebrate retina. Proc Natl Acad Sci U S A (1996) 4.81
Nectin and afadin: novel organizers of intercellular junctions. J Cell Sci (2003) 3.19
The genetic landscape of mutations in Burkitt lymphoma. Nat Genet (2012) 3.03
Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22. Nat Genet (1997) 3.03
Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines. Hum Mutat (2008) 3.02
Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature (2010) 2.85
Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. Dev Biol (2004) 2.65
Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell (2007) 2.61
Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat Genet (2003) 2.50
Emerging roles for E2F: beyond the G1/S transition and DNA replication. Cancer Cell (2003) 2.20
Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex. J Cell Biol (2002) 2.18
The transcriptome of retinal Müller glial cells. J Comp Neurol (2008) 2.17
Regulating proliferation during retinal development. Nat Rev Neurosci (2001) 2.06
Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization. Cancer Sci (2003) 2.03
Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1. Genome Res (2011) 2.00
Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat Genet (2004) 1.94
Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One (2008) 1.91
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci U S A (2012) 1.90
Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol (2007) 1.89
Quantitative analysis of proliferation and cell cycle length during development of the rat retina. Dev Dyn (1996) 1.88
Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. J Biol Chem (2003) 1.86
The search for the retinoblastoma cell of origin. Nat Rev Cancer (2005) 1.72
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Proc Natl Acad Sci U S A (2014) 1.71
Characterization of mammary tumors from Brg1 heterozygous mice. Oncogene (2007) 1.70
Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell (2011) 1.67
p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development (2000) 1.63
The identification of E2F1-specific target genes. Proc Natl Acad Sci U S A (2002) 1.63
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. J Cell Sci (2013) 1.55
Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol (2006) 1.54
Proximity interactions among centrosome components identify regulators of centriole duplication. Curr Biol (2014) 1.51
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 1.51
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc Natl Acad Sci U S A (2007) 1.50
SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Mol Biol Cell (2009) 1.41
Brg1 is required for murine neural stem cell maintenance and gliogenesis. Dev Biol (2005) 1.38
The zebrafish young mutation acts non-cell-autonomously to uncouple differentiation from specification for all retinal cells. Development (2000) 1.38
Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev (2008) 1.36
Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development (2005) 1.34
Positional cloning of the young mutation identifies an essential role for the Brahma chromatin remodeling complex in mediating retinal cell differentiation. Proc Natl Acad Sci U S A (2003) 1.29
Development and diversification of retinal amacrine interneurons at single cell resolution. Proc Natl Acad Sci U S A (2009) 1.29
Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development. Dev Biol (2006) 1.29
BRG1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells. Mol Cell Biol (2008) 1.28
Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation. Mol Cell Biol (2014) 1.28
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. Nat Genet (2012) 1.26
Targeted knockout of BRG1 potentiates lung cancer development. Cancer Res (2008) 1.24
Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors. Hum Mutat (2010) 1.24
Role of Rb family in the epigenetic definition of chromatin. Cell Cycle (2005) 1.23
Functional characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle. Hum Mol Genet (1999) 1.22
Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. Nat Struct Mol Biol (2011) 1.21
Genomic organisation and alternative splicing of human RIM1, a gene implicated in autosomal dominant cone-rod dystrophy (CORD7). Genomics (2003) 1.20
Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activity. Biochem Biophys Res Commun (2003) 1.17
Progression of neuronal and synaptic remodeling in the rd10 mouse model of retinitis pigmentosa. J Comp Neurol (2010) 1.15
Baf60c is a component of the neural progenitor-specific BAF complex in developing retina. Dev Dyn (2008) 1.12
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell (2013) 1.12
Neuronal differentiation and synaptogenesis in retinoblastoma. Cancer Res (2007) 1.10
Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners. Oncogene (2006) 1.09
Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina. J Comp Neurol (2003) 1.09
The extracellular matrix component WIF-1 is expressed during, and can modulate, retinal development. Mol Cell Neurosci (2004) 1.08
The roles of cadherins and nectins in interneuronal synapse formation. Curr Opin Neurobiol (2003) 1.06
The natural history of retinal degeneration in association with cobalamin C (cbl C) disease. Ophthalmic Genet (2006) 1.05
A detailed study of the phenotype of an autosomal dominant cone-rod dystrophy (CORD7) associated with mutation in the gene for RIM1. Br J Ophthalmol (2005) 1.02
Developmental defects in Rb-deficient retinae. Vision Res (2004) 1.02
Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus. J Comp Neurol (2003) 1.00
Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII. Blood (2010) 0.99
Validation of oligoarrays for quantitative exploration of the transcriptome. BMC Genomics (2008) 0.99
The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina. J Comp Neurol (2001) 0.98
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis. Genome Res (2014) 0.97
Mosaic deletion of Rb arrests rod differentiation and stimulates ectopic synaptogenesis in the mouse retina. J Comp Neurol (2006) 0.97
PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates. Gene (2012) 0.96
The cell adhesion gene PVRL3 is associated with congenital ocular defects. Hum Genet (2011) 0.96
An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity. Mol Cell Biol (2006) 0.96
The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. Mol Cell (2014) 0.96
Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn (2009) 0.95
Brg1 modulates enhancer activation in mesoderm lineage commitment. Development (2015) 0.94
Gene expression changes within Müller glial cells in retinitis pigmentosa. Mol Vis (2012) 0.93
Notch1 is required in newly postmitotic cells to inhibit the rod photoreceptor fate. Development (2013) 0.89
PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer. Genes Cancer (2012) 0.87
Regulation of PP2A activity by Mid1 controls cranial neural crest speed and gangliogenesis. Mech Dev (2012) 0.86
Glutamate regulates retinal progenitors cells proliferation during development. Eur J Neurosci (2006) 0.85
Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII). J Biol Chem (2013) 0.85
Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling. Dev Dyn (2013) 0.82
Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression. Oncotarget (2014) 0.78
In vivo function of the ER-Golgi transport protein LMAN1 in photoreceptor homeostasis. Adv Exp Med Biol (2014) 0.76
Centrosomes tune in to metabolic state and turn on to oxygen. Dev Cell (2013) 0.76
Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Rep (2014) 2.27
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer. Cell (2015) 1.84
Targeting oxidative stress in embryonal rhabdomyosarcoma. Cancer Cell (2013) 1.72
Targeting the DNA repair pathway in Ewing sarcoma. Cell Rep (2014) 1.09
Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma. Cancer Cell (2014) 0.98
Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Rep (2015) 0.92
Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors. Cell Stem Cell (2015) 0.89
Regulated lysosomal exocytosis mediates cancer progression. Sci Adv (2015) 0.83
Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway. Cell Rep (2015) 0.80
Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation. Sci Rep (2016) 0.75
Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data. Nucleic Acids Res (2019) 0.75
Evaluation of IFITM3 rs12252 Association with Severe Pediatric Influenza Infection. J Infect Dis (2017) 0.75