Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.

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Published in Nat Chem Biol on December 14, 2015

Authors

Luc de Waal1,2, Timothy A Lewis1, Matthew G Rees1, Aviad Tsherniak1, Xiaoyun Wu1, Peter S Choi1,2, Lara Gechijian1, Christina Hartigan1, Patrick W Faloon1, Mark J Hickey1, Nicola Tolliday1, Steven A Carr1, Paul A Clemons1, Benito Munoz1, Bridget K Wagner1, Alykhan F Shamji1, Angela N Koehler1,3, Monica Schenone1, Alex B Burgin1, Stuart L Schreiber4, Heidi Greulich1,2,5, Matthew Meyerson1,2,6

Author Affiliations

1: The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
2: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
3: Koch Institute for Integrative Cancer Research at MIT, Cambridge, Massachusetts, USA.
4: Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Harvard University, Cambridge, United States.
5: Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
6: Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

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