Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis.

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Published in N Engl J Med on December 24, 2015

Authors

Dominique Baeten1, Joachim Sieper, Jürgen Braun, Xenofon Baraliakos, Maxime Dougados, Paul Emery, Atul Deodhar, Brian Porter, Ruvie Martin, Mats Andersson, Shephard Mpofu, Hanno B Richards, MEASURE 1 Study Group, MEASURE 2 Study Group

Author Affiliations

1: From the Academic Medical Center, University of Amsterdam, Amsterdam (D.B.); Charité University Medicine Berlin, Berlin (J.S.), and Rheumazentrum Ruhrgebiet, Herne (J.B., X.B.) - both in Germany; Paris Descartes University and Department of Rheumatology, Hôpital Cochin, Paris (M.D.); Leeds Musculoskeletal Biomedical Research Unit, Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom (P.E.); Oregon Health and Science University, Portland (A.D.); Novartis Pharmaceuticals, East Hanover, NJ (B.P., R.M.); and Novartis Pharma, Basel, Switzerland (M.A., S.M., H.B.R.).

Associated clinical trials:

16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis (MEASURE 1) | NCT01358175

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis (MEASURE2) | NCT01649375

PsA Secukinumab XCT Structural Progression Study | NCT03623867

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