Published in Cell Cycle on February 01, 2016
Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res (1987) 10.80
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J (2001) 9.40
Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. Cell (1990) 9.24
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature (2011) 8.62
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell (2007) 8.47
Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med (1993) 7.67
Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med (2007) 6.52
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol (2011) 5.11
Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell (2009) 4.73
The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol (2009) 4.61
Oncogenic activation of NF-kappaB. Cold Spring Harb Perspect Biol (2010) 3.30
Recent progress in pancreatic cancer. CA Cancer J Clin (2013) 2.88
Protein phosphatase 2A: a panoply of enzymes. Curr Opin Cell Biol (2000) 2.80
The IKK complex: an integrator of all signals that activate NF-kappaB? Trends Cell Biol (2000) 2.68
Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends Mol Med (2008) 2.52
PP2A: unveiling a reluctant tumor suppressor. Cell (2007) 2.12
Tumor-associated macrophages: effectors of angiogenesis and tumor progression. Biochim Biophys Acta (2009) 2.05
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur J Immunol (2004) 1.50
Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis. Front Physiol (2014) 1.47
Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel. J Immunol (2007) 1.43
Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes. Proc Natl Acad Sci U S A (1988) 1.37
Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis. Cancer Sci (2010) 1.31
Corrupt policemen: inflammatory cells promote tumor angiogenesis. Curr Opin Oncol (2009) 1.29
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. Int J Cancer (2001) 1.24
The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR. Nucleic Acids Res (2011) 1.16
Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress. Arch Biochem Biophys (2002) 1.15
Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB. Mol Cancer Res (2009) 1.08
IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells. Cancer Biol Ther (2007) 1.08
PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway. Cancer Lett (2011) 1.04
Acute interstitial pancreatitis in rats induced by dibutyltin dichloride (DBTC): pathogenesis and natural course of lesions. Pancreas (1997) 1.03
Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-terminal kinase pathway. Eur J Cancer (2011) 1.02
Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. Cancer Sci (2008) 1.02
PP2A-Mediated Anticancer Therapy. Gastroenterol Res Pract (2013) 1.01
NF-κB-mediated miR-124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10. Oncotarget (2015) 0.96
Src as the link between inflammation and cancer. Front Physiol (2014) 0.95
Interleukin-6: a villain in the drama of pancreatic cancer development and progression. Hepatobiliary Pancreat Dis Int (2014) 0.93
Lipopolysaccharide: basic biochemistry, intracellular signaling, and physiological impacts in the gut. Intest Res (2014) 0.92
Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway. Oncotarget (2014) 0.92
Up-regulation of Krüppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. Mol Cancer Res (2009) 0.90
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia. Cardiovasc Res (2009) 0.90
Autocrine transforming growth factor β signaling regulates extracellular signal-regulated kinase 1/2 phosphorylation via modulation of protein phosphatase 2A expression in scleroderma fibroblasts. Fibrogenesis Tissue Repair (2010) 0.88
Targeted noninvasive imaging of EGFR-expressing orthotopic pancreatic cancer using multispectral optoacoustic tomography. Cancer Res (2014) 0.87
Tumor-derived prostaglandin E2 and transforming growth factor-beta stimulate endothelial cell motility through inhibition of protein phosphatase-2A and involvement of PTEN and phosphatidylinositide 3-kinase. Angiogenesis (2004) 0.87
Tissue homogenization as a key step in extracting RNA from human and rat pancreatic tissue. Biotechniques (1997) 0.86
A novel pathway responsible for lipopolysaccharide-induced translational regulation of TNF-α and IL-6 expression involves protein kinase C and fascin. J Immunol (2011) 0.85
Expression of transforming growth factor beta1, beta2, and beta3 in chronic, cancer-associated, obstructive pancreatitis. Arch Pathol Lab Med (2006) 0.85
Plasma interleukin-11 (IL-11) levels have diagnostic and prognostic roles in patients with pancreatic cancer. Tumour Biol (2014) 0.81
Protocatechuic acid inhibits lung cancer cells by modulating FAK, MAPK, and NF-κB pathways. Nutr Cancer (2014) 0.81
Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol (2014) 0.80
The association between expressions of Ras and CD68 in the angiogenesis of breast cancers. Cancer Cell Int (2015) 0.80
Induction of nitric oxide synthase expression by lipopolysaccharide is mediated by calcium-dependent PKCα-β1 in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol (2013) 0.80
Lotus leaf (Nelumbo nucifera) and its active constituents prevent inflammatory responses in macrophages via JNK/NF-κB signaling pathway. Am J Chin Med (2014) 0.79
Macrophages facilitate coal tar pitch extract-induced tumorigenic transformation of human bronchial epithelial cells mediated by NF-κB. PLoS One (2012) 0.78
Protein phosphatase-2A is down-regulated in patients within clear cell renal cell carcinoma. Int J Clin Exp Pathol (2014) 0.77
Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway. Braz J Med Biol Res (2014) 0.76
KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-κB and VEGF-C. Anticancer Res (2014) 0.76