Fibroblast Cell-Based Therapy for Experimental Autoimmune Diabetes.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 26765526)

Published in PLoS One on January 14, 2016

Authors

Reza B Jalili1, Yun Zhang1, Azadeh Hosseini-Tabatabaei1, Ruhangiz T Kilani1, Mohsen Khosravi Maharlooei1, Yunyuan Li1, Sanam Salimi Elizei1, Garth L Warnock1, Aziz Ghahary1

Author Affiliations

1: Department of Surgery, University of British Columbia, Vancouver, BC, Canada.

Articles cited by this

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol (2012) 7.26

CCR7 and its ligands: balancing immunity and tolerance. Nat Rev Immunol (2008) 5.35

Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med (1999) 5.26

Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature (2010) 5.16

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells. J Immunol (2006) 3.84

Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science (2003) 2.50

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J Clin Invest (2003) 2.37

Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol (2012) 2.37

Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells. J Immunol (2007) 2.19

Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A (2007) 2.10

IDO and tolerance to tumors. Trends Mol Med (2004) 2.03

Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science (1995) 2.01

The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells. J Immunol (2007) 1.89

Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science (2006) 1.88

Mesenchymal stem cells: the fibroblasts' new clothes? Haematologica (2008) 1.87

Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science (2006) 1.69

The role of the PD-1 pathway in autoimmunity and peripheral tolerance. Ann N Y Acad Sci (2011) 1.67

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling. J Exp Med (2011) 1.63

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med (2003) 1.62

Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo. J Immunol (2005) 1.58

Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa. J Immunol (2006) 1.50

Indoleamine 2,3 dioxygenase and regulation of T cell immunity. Biochem Biophys Res Commun (2005) 1.50

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells. BMC Med (2012) 1.44

Stem cell therapy for type 1 diabetes mellitus. Nat Rev Endocrinol (2010) 1.21

Tryptophan catabolism generates autoimmune-preventive regulatory T cells. Transpl Immunol (2006) 1.12

Mechanisms of PDL1-mediated regulation of autoimmune diabetes. Clin Immunol (2007) 1.11

Autoimmunity and beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough. Ann N Y Acad Sci (2007) 1.08

Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol (2010) 1.04

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol (2007) 1.04

Antigen-presenting capacity of rheumatoid synovial fibroblasts. Immunology (1994) 1.01

Dendritic cells pulsed with antigen-specific apoptotic bodies prevent experimental type 1 diabetes. Clin Exp Immunol (2009) 1.01

Indoleamine 2,3-dioxygenase and regulatory function: tryptophan starvation and beyond. Methods Mol Biol (2011) 0.99

Antigen-presenting cells. Professionals and amateurs. Curr Biol (1995) 0.97

Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells. Gastroenterology (2011) 0.96

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. J Exp Med (2009) 0.93

Stem cell therapy to cure type 1 diabetes: from hype to hope. Stem Cells Transl Med (2013) 0.93

Type 1 diabetes immunotherapy: is the glass half empty or half full? Sci Transl Med (2011) 0.93

Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care (2011) 0.93

Local expression of indoleamine 2,3 dioxygenase in syngeneic fibroblasts significantly prolongs survival of an engineered three-dimensional islet allograft. Diabetes (2010) 0.90

Fibroblast populated collagen matrix promotes islet survival and reduces the number of islets required for diabetes reversal. J Cell Physiol (2011) 0.90

Skin fibroblasts are potent suppressors of inflammation in experimental arthritis. Ann Rheum Dis (2011) 0.86

Stem cell-based treatments for Type 1 diabetes mellitus: bone marrow, embryonic, hepatic, pancreatic and induced pluripotent stem cells. Diabet Med (2012) 0.86

Antigen-presenting-cell function of interferon gamma-treated human gingival fibroblasts. J Periodontal Res (1996) 0.86

Co-transplantation of autologous MSCs delays islet allograft rejection and generates a local immunoprivileged site. Acta Diabetol (2015) 0.86

Antigen-specific therapeutic approaches in Type 1 diabetes. Cold Spring Harb Perspect Med (2012) 0.85

Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol (2013) 0.84

Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute. Wound Repair Regen (2010) 0.83

IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells. Immunobiology (2013) 0.82

Antigen-presenting properties of gingival fibroblasts in chronic adult periodontitis. Clin Exp Immunol (1997) 0.81

Mechanism underlying defective interferon gamma-induced IDO expression in non-obese diabetic mouse fibroblasts. PLoS One (2012) 0.81

Highly efficient stable expression of indoleamine 2,3 dioxygenase gene in primary fibroblasts. Biol Proced Online (2010) 0.81

The potential role of dendritic cells in the therapy of Type 1 diabetes. Immunotherapy (2013) 0.81

The potential of cell-based therapy for diabetes and diabetes-related vascular complications. Curr Diab Rep (2014) 0.78

Rodent versus human insulitis: why the huge disconnect? Curr Opin Endocrinol Diabetes Obes (2015) 0.76