Published in EMBO J on January 18, 2016
Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis. EMBO J (2016) 1.10
Pro-apoptotic Bax molecules densely populate the edges of membrane pores. Sci Rep (2016) 0.82
Pore formation by dimeric Bak and Bax: an unusual pore? Philos Trans R Soc Lond B Biol Sci (2017) 0.80
Apoptotic foci at mitochondria: in and around Bax pores. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes Dev (2016) 0.77
In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy. Sci Rep (2016) 0.77
Relationship Between β-Amyloid and Mitochondrial Dynamics. Cell Mol Neurobiol (2016) 0.76
From single molecules to life: microscopy at the nanoscale. Anal Bioanal Chem (2016) 0.76
Necroptosis Execution Is Mediated by Plasma Membrane Nanopores Independent of Calcium. Cell Rep (2017) 0.76
Assembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic pore. Sci Rep (2016) 0.76
Doughnuts, daisy chains and crescent moons: the quest for the elusive apoptotic pore. EMBO J (2016) 0.76
The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation. Sci Rep (2016) 0.75
Inhibition of Malaria Infection in Transgenic Anopheline Mosquitoes Lacking Salivary Gland Cells. PLoS Pathog (2016) 0.75
Disrupting a key hydrophobic pair in the oligomerization interface of the actinoporins impairs their pore-forming activity. Protein Sci (2017) 0.75
Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes. Proc Natl Acad Sci U S A (2016) 0.75
Real-time visualization of perforin nanopore assembly. Nat Nanotechnol (2017) 0.75
Mitochondrial apoptosis and BH3 mimetics. F1000Res (2016) 0.75
Disordered clusters of Bak dimers rupture mitochondria during apoptosis. Elife (2017) 0.75
Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane. Sci Rep (2016) 0.75
BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells. Prog Retin Eye Res (2017) 0.75
Bax mitochondrial relocation is linked to its phosphorylation and its interaction with Bcl-xL. Microb Cell (2016) 0.75
Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation. Nat Commun (2017) 0.75
Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis. PLoS One (2017) 0.75
Resveratrol ameliorates hypoxia/ischemia-induced brain injury in the neonatal rat via the miR-96/Bax axis. Childs Nerv Syst (2017) 0.75
BCL-2 family: integrating stress responses at the ER to control cell demise. Cell Death Differ (2017) 0.75
Conformational Heterogeneity in the Activation Mechanism of Bax. Structure (2017) 0.75
Bacterial tail anchors can target to the mitochondrial outer membrane. Biol Direct (2017) 0.75
BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove. Proc Natl Acad Sci U S A (2017) 0.75
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (2001) 23.42
Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. Opt Lett (1994) 14.32
Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol (1997) 9.18
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell (2000) 8.95
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell (2002) 8.38
Structure of Bax: coregulation of dimer formation and intracellular localization. Cell (2000) 7.00
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell (2008) 5.75
Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria. Biochem J (2000) 3.62
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol. Cell (2011) 3.23
Nanoscale resolution in GFP-based microscopy. Nat Methods (2006) 3.19
Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat Methods (2006) 3.12
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis. EMBO J (2005) 3.11
To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. Mol Cell (2008) 2.97
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis. Cell (2013) 2.75
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission. Nat Struct Mol Biol (2010) 2.27
Cascades of transient pores in giant vesicles: line tension and transport. Biophys J (2003) 2.19
A simple, versatile method for GFP-based super-resolution microscopy via nanobodies. Nat Methods (2012) 2.04
Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. J Biol Chem (2002) 2.00
Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration. Proc Natl Acad Sci U S A (2006) 1.87
Structural model of active Bax at the membrane. Mol Cell (2014) 1.81
Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion. Cell Tissue Res (2001) 1.69
Bax dimerizes via a symmetric BH3:groove interface during apoptosis. Cell Death Differ (2011) 1.60
Molecular details of Bax activation, oligomerization, and membrane insertion. J Biol Chem (2009) 1.60
Membrane-insertion fragments of Bcl-xL, Bax, and Bid. Biochemistry (2004) 1.56
Binding-activated localization microscopy of DNA structures. Nano Lett (2011) 1.48
The secrets of the Bcl-2 family. Cell Death Differ (2012) 1.48
Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM. Biophys J (2007) 1.37
Bax forms an oligomer via separate, yet interdependent, surfaces. J Biol Chem (2010) 1.27
Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins. Biophys J (2005) 1.19
Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation. Cell Death Differ (2009) 1.18
Dynamics and structure of the Bax-Bak complex responsible for releasing mitochondrial proteins during apoptosis. J Cell Sci (2008) 1.17
Pores formed by Baxα5 relax to a smaller size and keep at equilibrium. Biophys J (2010) 1.16
Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers. J Biol Chem (2013) 1.16
Nanoscopy in a living multicellular organism expressing GFP. Biophys J (2011) 1.16
Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin. Elife (2014) 1.15
Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis. EMBO J (2016) 1.10
Membrane pore formation at protein-lipid interfaces. Trends Biochem Sci (2014) 1.06
Incomplete pneumolysin oligomers form membrane pores. Open Biol (2014) 1.06
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species. Nat Commun (2015) 1.02
Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size. J Biol Chem (2013) 1.01
Three-dimensional structure of Bax-mediated pores in membrane bilayers. Cell Death Dis (2013) 1.00
Mechanistic differences in the membrane activity of Bax and Bcl-xL correlate with their opposing roles in apoptosis. Biophys J (2013) 0.99
Cardiolipin effects on membrane structure and dynamics. Langmuir (2013) 0.99
Biophysical characterization of the oligomeric state of Bax and its complex formation with Bcl-XL. Biochem Biophys Res Commun (1999) 0.92
Dynamic interaction of cBid with detergents, liposomes and mitochondria. PLoS One (2012) 0.91
Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes. Cell Death Differ (2014) 0.89
Cell-to-cell variability in cell death: can systems biology help us make sense of it all? Cell Death Dis (2014) 0.87
Assembly of streptolysin O pores assessed by quartz crystal microbalance and atomic force microscopy provides evidence for the formation of anchored but incomplete oligomers. Biochim Biophys Acta (2015) 0.84
More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes. J Membr Biol (2015) 0.83