Published in Free Radic Biol Med on January 01, 1989
Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev (2014) 2.66
Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells. Proc Natl Acad Sci U S A (1993) 1.39
Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry. Rapid Commun Mass Spectrom (2003) 1.31
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. J Biol Chem (2010) 1.28
The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysis. Redox Biol (2013) 1.10
Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. Chem Res Toxicol (2010) 1.07
NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production. J Biol Inorg Chem (2007) 0.91
Role of lipid peroxidation and antioxidant enzymes in omega 3 fatty acids induced suppression of breast cancer xenograft growth in mice. Cancer Cell Int (2002) 0.89
Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. Chem Biol Interact (2011) 0.87
Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency. J Clin Invest (1997) 0.87
Bile acid-induced elevated oxidative stress in the absence of farnesoid X receptor. Biol Pharm Bull (2009) 0.85
Age-associated, oxidatively modified proteins: A critical evaluation. Age (Omaha) (1997) 0.84
Mass spectrometry of fatty aldehydes. Biochim Biophys Acta (2011) 0.83
Levels of salivary antioxidant vitamins and lipid peroxidation in patients with oral lichen planus and healthy individuals. Chonnam Med J (2014) 0.82
ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations. J Am Chem Soc (2014) 0.82
Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. Anal Bioanal Chem (2010) 0.81
Time-course changes of oxidative stress response to high-intensity discontinuous training versus moderate-intensity continuous training in masters runners. PLoS One (2014) 0.81
Protective effect of magnesium on renal function in STZ-induced diabetic rats. J Diabetes Metab Disord (2014) 0.81
Enhancement of the stability of a prolipase from Rhizopus oryzae toward aldehydes by saturation mutagenesis. Appl Environ Microbiol (2007) 0.80
Formation of 4-hydroxynonenal and further aldehydic mediators of inflammation during bromotrichlorornethane treatment of rat liver cells. Mediators Inflamm (1993) 0.80
Possible role of lipid peroxidation in the induction of NF-kappa B and AP-1 in RFL-6 cells by crocidolite asbestos: evidence following protection by vitamin E. Environ Health Perspect (1997) 0.79
CYP1A1 induction in the colon by serum: involvement of the PPARα pathway and evidence for a new specific human PPREα site. PLoS One (2011) 0.79
Effects of maté tea intake on ex vivo LDL peroxidation induced by three different pathways. Nutrients (2009) 0.76
LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress. Curr Protoc Toxicol (2011) 0.76
Inactivation of ethanol-inducible cytochrome P450 and other microsomal P450 isozymes by trans-4-hydroxy-2-nonenal, a major product of membrane lipid peroxidation. Proc Natl Acad Sci U S A (1995) 0.75
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med (1991) 16.01
The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med (1992) 3.52
Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic Res Commun (1989) 2.81
Cytotoxicity and genotoxicity of lipid-oxidation products. Am J Clin Nutr (1993) 2.06
Biochemical, structural, and functional properties of oxidized low-density lipoprotein. Chem Res Toxicol (1991) 1.82
Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am J Clin Nutr (1991) 1.41
Reaction of glutathione with conjugated carbonyls. Z Naturforsch C (1975) 1.39
Possible mutagens derived from lipids and lipid precursors. Mutat Res (1990) 1.38
Estimation of peroxidative damage. A critical review. Pathol Biol (Paris) (1996) 1.34
Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions. Biochem J (1985) 1.16
Chemistry and pathophysiology of oxidation of LDL. Rev Physiol Biochem Pharmacol (1996) 1.11
Lipid peroxidation and its role in atherosclerosis. Br Med Bull (1993) 1.08
The role of vitamin E and carotenoids in preventing oxidation of low density lipoproteins. Ann N Y Acad Sci (1989) 1.07
Effect of antioxidants on oxidative modification of LDL. Ann Med (1991) 1.05
Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product. J Lipid Res (1997) 1.00
Endogenous antioxidants and lipoprotein oxidation. Biochem Soc Trans (1990) 0.93
The metabolism of 4-hydroxynonenal, a lipid peroxidation product, is dependent on tumor age in Ehrlich mouse ascites cells. EXS (1992) 0.90
Regulation of urea synthesis. The effect of ammonia on the N-acetylglutamate content of isolated rat liver cells. Biochim Biophys Acta (1981) 0.89
Effect of oxidative stress by iron on 4-hydroxynonenal formation and proliferative activity in hepatomas of different degrees of differentiation. Free Radic Biol Med (1997) 0.86
Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in Ehrlich mouse ascites cells at different proliferation stages. Cancer Res (1994) 0.86
[Experiments on the therapeutical effect of 4-hydroxypentenal. 3. Inhibition of the growth of solid nemeth-kellner-lymphoma]. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol (1971) 0.86
[Experiments on the therapeutic effect of hydroxypentenal. II. Inhibition of the growth of sarcoma 180]. Z Krebsforsch (1971) 0.85
Effects of cinnabarinic acid on mitochondrial respiration. Biochem Pharmacol (1976) 0.84
Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by enterocytes of rat small intestine. Biochem Int (1991) 0.82
Relationships among oxidation of low-density lipoprotein, antioxidant protection, and atherosclerosis. Adv Pharmacol (1997) 0.81
Ornithine uptake by isolated hepatocytes and distribution within the cell. Int J Biochem (1984) 0.80
Inhibition of LDL oxidation by antioxidants. EXS (1992) 0.78
The effect of glucagon on N-acetylglutamate-synthetase. Int J Biochem (1985) 0.78
Inhibition of some mitochondrial functions by acrolein and methylvinylketone. Biochem Pharmacol (1973) 0.77
Effect of methoxy-p-benzoquinones and methoxy-p-hydroquinones on DNA synthesis in Ehrlich ascites tumor cells. Acta Biochim Biophys Hung (1987) 0.77
The impact of diets with different magnesium contents on magnesium and calcium in serum and tissues of the rat. Life Sci (2000) 0.77
The inhibitory effect of 4-hydroxy-nonenal on DNA-polymerases alpha and beta from rat liver and rapidly dividing Yoshida ascites hepatoma. Cell Biochem Funct (1986) 0.77
Regulation of the n-acetylglutamate content of rat hepatocytes by the glutamate concentration. Adv Exp Med Biol (1982) 0.77
Metabolism of 4-hydroxynonenal by the rat hepatoma cell line MH1C1. Cell Biochem Funct (1988) 0.76
Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets. Chem Biol Interact (1987) 0.76
Modification of human low density lipoprotein by lipid peroxidation. Basic Life Sci (1988) 0.75
[On the different response of succinate-oxydation and of succinodehydrogenase to the action of 4-hydroxypentenal in Ehrlich-ascites-tumor and normal liver-cells]. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol (1973) 0.75
[Structure and activity of insulin. 8. Exchange of histidine for alanine in synthetic B-chains]. Hoppe Seylers Z Physiol Chem (1970) 0.75
[Structure and activity of insulin. VII. Shortened synthetic B-chains]. Hoppe Seylers Z Physiol Chem (1969) 0.75
[Relationship between Chemical Constitution and Theraeutic Activity of alpha, beta-unsaturated Aldehydes in the Ehrlich-Solid-Tumor of the Mouse]. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol (1975) 0.75
Vitamin E and atherosclerosis: an overview. J Nutr Sci Vitaminol (Tokyo) (1992) 0.75
Does ornithine stimulate carbamoylphosphate synthetase? Int J Biochem (1985) 0.75