Human Liver Progenitor Cells for Liver Repair.

Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev (2003) 11.29

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix. Nat Med (2010) 7.11

EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology (2008) 5.53

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat Biotechnol (2007) 5.04

Human hepatic stem cells from fetal and postnatal donors. J Exp Med (2007) 4.15

Mechanisms involved in the therapeutic properties of mesenchymal stem cells. Cytokine Growth Factor Rev (2009) 3.73

CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int J Cancer (2007) 3.65

Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds. Annu Rev Biomed Eng (2011) 3.16

The phenotypes of pluripotent human hepatic progenitors. Stem Cells (2006) 2.41

Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proc Natl Acad Sci U S A (2006) 2.32

Isolation and characterization of a stem cell population from adult human liver. Stem Cells (2006) 2.25

The use of whole organ decellularization for the generation of a vascularized liver organoid. Hepatology (2011) 2.09

Rescue of lethal hepatic failure by hepatized lymph nodes in mice. Gastroenterology (2010) 2.02

Human hepatic stem cell and maturational liver lineage biology. Hepatology (2011) 1.99

Engineering functional two- and three-dimensional liver systems in vivo using hepatic tissue sheets. Nat Med (2007) 1.96

Human fetal liver-derived stem cell transplantation as supportive modality in the management of end-stage decompensated liver cirrhosis. Cell Transplant (2010) 1.94

The stem cell niche of human livers: symmetry between development and regeneration. Hepatology (2008) 1.94

Identification of bipotential progenitor cells in human liver development. Hepatology (1996) 1.84

Mesenchymal stem cell effects on T-cell effector pathways. Stem Cell Res Ther (2011) 1.76

Cell transplantation in the treatment of liver diseases. Pediatr Transplant (2008) 1.75

Portal vein embolization and autologous CD133+ bone marrow stem cells for liver regeneration: initial experience. Radiology (2007) 1.74

The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting. Mutat Res (1995) 1.50

Isolation of human progenitor liver epithelial cells with extensive replication capacity and differentiation into mature hepatocytes. J Cell Sci (2002) 1.49

Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds. Hepatology (2010) 1.48

In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art. Stem Cells (2009) 1.46

Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver. Gastroenterology (2002) 1.33

Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant (2012) 1.31

Hepatocyte transplantation in a 4-year-old girl with peroxisomal biogenesis disease: technique, safety, and metabolic follow-up. Transplantation (2003) 1.31

Current status of hepatocyte transplantation. Transplantation (2012) 1.28

Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation. Hepatology (2009) 1.23

Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium. Hepatology (1999) 1.23

Sustained engraftment and tissue enzyme activity after liver cell transplantation for argininosuccinate lyase deficiency. Gastroenterology (2006) 1.23

Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates. Hepatology (2010) 1.22

In vivo tracking of 111In-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis. Nucl Med Biol (2011) 1.22

Stem cells in liver diseases and cancer: recent advances on the path to new therapies. Hepatology (2012) 1.21

Hepatocyte transplantation-induced liver inflammation is driven by cytokines-chemokines associated with neutrophils and Kupffer cells. Gastroenterology (2009) 1.21

Identification of expandable human hepatic progenitors which differentiate into mature hepatic cells in vivo. Gut (2005) 1.18

Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. Am J Pathol (2009) 1.18

Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes? Cell Transplant (2007) 1.17

Human hepatocyte transplantation. Methods Mol Biol (2010) 1.17

Monocrotaline promotes transplanted cell engraftment and advances liver repopulation in rats via liver conditioning. Hepatology (2006) 1.15

Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases. Hepatology (2005) 1.14

Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside? Gut (2008) 1.12

Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat. Hepatology (2005) 1.12

Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity. Theranostics (2012) 1.08

Integrin and extracellular matrix interactions regulate engraftment of transplanted hepatocytes in the rat liver. Gastroenterology (2005) 1.07

Hepatic sinusoidal vasodilators improve transplanted cell engraftment and ameliorate microcirculatory perturbations in the liver. Hepatology (2002) 1.06

Cell delivery: from cell transplantation to organ engineering. Cell Transplant (2010) 1.06

Long-term culture of functional liver tissue: three-dimensional coculture of primary hepatocytes and stellate cells. Tissue Eng (2003) 1.02

Side population cells derived from adult human liver generate hepatocyte-like cells in vitro. Dig Dis Sci (2005) 1.02

Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture. Hepatology (2012) 1.02

Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche. Biomaterials (2011) 1.01

Cryopreserved liver cell transplantation controls ornithine transcarbamylase deficient patient while awaiting liver transplantation. Am J Transplant (2005) 1.00

The instant blood-mediated inflammatory reaction characterized in hepatocyte transplantation. Transplantation (2011) 0.99

Hepatocyte cryopreservation: is it time to change the strategy? World J Gastroenterol (2010) 0.98

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells. PLoS One (2011) 0.98

In vitro differentiated adult human liver progenitor cells display mature hepatic metabolic functions: a potential tool for in vitro pharmacotoxicological testing. Cell Transplant (2010) 0.98

Expression of hepatocyte and oval cell antigens in hepatocellular carcinomas produced by oncogene-transfected liver epithelial cells. Cancer Res (1990) 0.98

Tissue factor-dependent procoagulant activity of isolated human hepatocytes: relevance to liver cell transplantation. Liver Transpl (2007) 0.96

Variant forms of alpha-fetoprotein transcripts expressed in human hematopoietic progenitors. Implications for their developmental potential towards endoderm. J Biol Chem (2002) 0.96

The quest for liver progenitor cells: a practical point of view. J Hepatol (2009) 0.95

Surgically relevant aspects of stem cell paracrine effects. Surgery (2008) 0.95

Impact of indium-111 oxine labelling on viability of human mesenchymal stem cells in vitro, and 3D cell-tracking using SPECT/CT in vivo. Mol Imaging Biol (2011) 0.95

Cryopreservation of human hepatocytes alters the mitochondrial respiratory chain complex 1. Cell Transplant (2007) 0.94

Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold. Biomaterials (2006) 0.94

Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells. Int J Biochem Cell Biol (2010) 0.94

Treatment of Crigler-Najjar Syndrome type 1 by hepatic progenitor cell transplantation: a simple procedure for management of hyperbilirubinemia. Transplant Proc (2008) 0.93

Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells. Cell Cycle (2011) 0.93

Hepatic progenitor cells from adult human livers for cell transplantation. Gut (2008) 0.93

Adult-derived human liver progenitor cells in long-term culture maintain appropriate gatekeeper mechanisms against transformation. Cell Transplant (2012) 0.93

Growth ability and repopulation efficiency of transplanted hepatic stem cells, progenitor cells, and mature hepatocytes in retrorsine-treated rat livers. Cell Transplant (2011) 0.92

Efficient hepatocyte engraftment and long-term transgene expression after reversible portal embolization in nonhuman primates. Hepatology (2009) 0.92

Management of hyperbilirubinemia in biliary atresia by hepatic progenitor cell transplantation through hepatic artery: a case report. Transplant Proc (2008) 0.92

Liver cell transplantation. Minerva Pediatr (2005) 0.92

Activation of serotonin receptor-2B rescues small-for-size liver graft failure in mice. Hepatology (2011) 0.91

Bivalirudin in combination with heparin to control mesenchymal cell procoagulant activity. PLoS One (2012) 0.91

Hepatic stellate cells promote hepatocyte engraftment in rat liver after prostaglandin-endoperoxide synthase inhibition. Gastroenterology (2009) 0.91

Cell-mediated rejection results in allograft loss after liver cell transplantation. Liver Transpl (2008) 0.91

Isolation and characterization of adult human liver progenitors from ischemic liver tissue derived from therapeutic hepatectomies. Tissue Eng Part A (2009) 0.89

Ex vivo conditions for self-replication of human hepatic stem cells. Tissue Eng Part C Methods (2008) 0.89

New insights into liver regeneration. Clin Res Hepatol Gastroenterol (2011) 0.89

Deceleration of regenerative response improves the outcome of rat with massive hepatectomy. Am J Transplant (2010) 0.89

Hepatic targeting and biodistribution of human fetal liver stem/progenitor cells and adult hepatocytes in mice. Hepatology (2009) 0.88

Cryopreservation of human fetal liver hematopoietic stem/progenitor cells using sucrose as an additive to the cryoprotective medium. Cryobiology (2008) 0.88

Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver. Stem Cells (2007) 0.88

Chromosomal damage rate, aging, and diet. Ann N Y Acad Sci (1998) 0.88

The influence of donor age on liver regeneration and hepatic progenitor cell populations. Surgery (2011) 0.87

Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation. Lab Invest (1994) 0.87

Autologous bone marrow stem cells in the treatment of chronic liver disease. Int J Hepatol (2011) 0.86

Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts. Hepatology (2013) 0.86

Induction of umbilical cord blood-derived beta2m-c-Met+ cells into hepatocyte-like cells by coculture with CFSC/HGF cells. Liver Transpl (2005) 0.85

Adult human hepatocytes promote CD4(+) T-cell hyporesponsiveness via interleukin-10-producing allogeneic dendritic cells. Cell Transplant (2014) 0.85

From hepatocytes to stem and progenitor cells for liver regenerative medicine: advances and clinical perspectives. Cell Prolif (2011) 0.83

Characterization of hepatic progenitors from human fetal liver during second trimester. World J Gastroenterol (2008) 0.81

Emerging insights into liver-directed cell therapy for genetic and acquired disorders. Transpl Immunol (2004) 0.81

Co-transplantation of human mesenchymal stem cells promotes human CD34+ cells engraftment in a dose-dependent fashion in NOD/SCID mice. J Korean Med Sci (2007) 0.80

Fractionated external beam radiotherapy as a suitable preparative regimen for hepatocyte transplantation after partial hepatectomy. Int J Radiat Oncol Biol Phys (2011) 0.80

Transplantation of microencapsulated umbilical-cord-blood-derived hepatic-like cells for treatment of hepatic failure. World J Gastroenterol (2011) 0.80

Improved cryopreservation of human hepatocytes using a new xeno free cryoprotectant solution. World J Hepatol (2012) 0.79

Steatotic liver: a suitable source for the isolation of hepatic progenitor cells. Liver Int (2011) 0.79